Review article.A review of the literature on postoperative initiation thrombophylactic agents following spine surgery.A and synthesis data to provide an update venous thromboprophylaxis surgery.Postoperative regimens measures surgery remain a controversial issue. Recommendations regarding mechanical versus chemical prophylaxis vary greatly among institutions.Postoperative remains optimal timing agent selection. The benefits deep vein thrombosis/pulmonary embolism must be weighed against...

Literature review.Preoperative management of therapeutic anticoagulation in spine surgery is critical to minimize risk thromboembolic events yet prevent postsurgical complications. Limited research available, and most guidelines are based on drug half-lives. We aim clarify current available evidence for safe practice this patient population.A literature search PubMed was done encompassing comprehensive terms locate published surgery. Predefined inclusion exclusion criteria were applied data...

Cavernous angiomas (CAs) are benign vascular malformations predominantly seen in the brain parenchyma and therefore referred to as intra-axial. Extra-axial dural-based cavernous angiomas, on other hand, rare lesions found outside of parenchyma. They occur middle fossa may be easily misdiagnosed meningiomas due their extra-axial location. In addition, CAs that located fossa, such convexity, have a better prognosis since they more surgically accessible. Surgical resection is main treatment...

Review article.A review of the literature evaluating cost-effectiveness undergoing adult spinal deformity surgery and potential avenues for reducing costs.A current synthesis data to provide an update on cost effectiveness surgery.Compared with nonoperative management, operative management is associated improved patient-reported outcomes quality life; however, it significant financial resource use.Operative has been shown be effective but utilization. The optimal treatment highly dependent...

The authors report 2 cases of sacral dural arteriovenous fistula (AVF) presenting with gradual neurologic decline characterized by progressive lower extremity weakness and bowel bladder incontinence. Spinal angiography demonstrated a AVF perimedullary vein engorgement drainage extending to the level cervical spine in both cases. fistulas were completely obliterated n-BCA (<i>n</i>-butyl cyanoacrylate) embolic agent one case, ethylene vinyl alcohol (Onyx) second, resulting...

This operative video details the treatment of cervical radiculopathy caused by unilateral foraminal stenosis through a microendoscopic posterior foraminotomy in sitting position using TELIGEN system. A 67-year-old male patient presented with C6-7 imaging corroborating severe stenosis. Therefore, was recommended rather than an anterior diskectomy and fusion or arthroplasty to preserve segmental motion minimize hardware-related complications. reviews nuances this approach key surgical steps....

Glioependymal cysts are rare congenital lesions of the central nervous system. Reported surgical treatments these have varied and yielded mixed results, optimal strategy is still controversial. The authors here report clinical outcomes for three adult patients successfully treated with neuroendoscopic fenestration into ventricular had presented symptomatic glioependymal in period from 2013 to 2016 at authors’ institution. All underwent minimally invasive cyst lateral ventricle via a...

Myxomas are rare, locally infiltrative, benign neoplasms of mesenchymal origin. Although benign, these tumors aggressive with a high rate recurrence following conservative resection. Their relative infrequency, variable location, and insidious growth present diagnostic challenge to clinicians. Cases myxomas have been described throughout the body, but intraosseous orbit exceedingly rare.We report case 53-year-old male history chronic sinusitis symptoms hyposmia bifrontal headaches refractory...

Lumbar interbody fusion is a common spine procedure. 199,140 elective lumbar fusions were performed in the United States 2015. Robot assisted (RA) pedicle screw placement has advanced minimally invasive surgery (MIS) making short stay transforaminal (TLIF) with same day or next discharge possibility for select patients.This study retrospective case series of single surgeon's experience RA MIS TLIF using Globus ExcelsiusGPS system. Patients undergoing at an outpatient center between August...

Background Dural sinus diverticula are a rare vascular etiology of pulsatile tinnitus. Patients typically present with disabling symptoms and undergo an extensive workup for common causes Endovascular treatment has been shown to be effective in several case reports. We the largest series eight patients treated endovascular therapy using stent-assisted coiling describe unique details intervention. Methods A retrospective chart review was performed on all who underwent dural stenting. Results...

To report on the successful treatment of idiopathic intracranial hypertension (IIH) in a patient with venous sinus stenosis secondary to persistent occipital-marginal (POMS) utilizing stenting.A 55-year-old female presented headaches and blurry vision. Ophthalmologic examination demonstrated papilledema. Two lumbar punctures opening pressures 31 38 cmH2O provided temporary symptom relief. Cerebral venography hypoplastic bilateral transverse-sigmoid sinuses dominant drainage through (POMS)....

Alvarado, Anthony MD; Boyle, Jacqueline BS; Martinez, Derek Avellino, M. MD, MBA; Lin, Julian MD Author Information

Abstract Glioblastoma (GBM) is the most common malignant primary brain tumor and remains challenging to treat due its aggressive nature with high rate of recurrence. Despite advances in therapy, prognosis poor median survival 19 months maximal therapy. The normal astrocytes within GBM TME undergo a phenotypic shift, promoting alterations supportive growth. There increasing attention on role tumor-associated (TAA) progression resistance Previous studies assessing astrocyte support employ...

Dr. Alvarado is a Neurosurgery Spine Fellow, and O'Toole Professor, Department of Neurological Surgery, Rush University, 1725 W. Harrison St, Ste 855, Chicago, IL; E-mail: [email protected]. consultant receives royalties from Globus Medical Inc. This work supported by the Research & Education Foundation (2023-24 Clinical Fellowship Grant). Lippincott CME Institute has identified mitigated all relevant financial relationships regarding this educational activity. The remaining author, faculty,...