A5031661765- Neural dynamics and brain function
- Memory and Neural Mechanisms
- Cognitive Science and Mapping
- Neuroscience and Neural Engineering
- Zebrafish Biomedical Research Applications
- Photoreceptor and optogenetics research
- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
Humboldt-Universität zu Berlin
2016-2024
Charité - Universitätsmedizin Berlin
2019
Abstract Here, we describe an automated optical method for tracking animal behavior in both head-fixed and freely moving animals, real time offline. It takes advantage of off-the-shelf camera system, the Pixy camera, designed as a fast vision sensor robotics that uses color-based filtering algorithm at 50 Hz to track objects. Using customized software, demonstrate versatility our approach by first rostro-caudal motion individual adjacent row (D1, D2) or arc whiskers (β, γ), single whisker...
A central function of the brain is to plan, predict, and imagine effect movement in a dynamically changing environment. Here we show that mice head-fixed plus-maze, floating on air, trained pick lanes based visual stimuli, asymmetric movement, position whiskers two sides face signals whether animal moving, turning, expecting reward, or licking. We (1) whisking asymmetry coordinated with behavioral state, state can be decoded predicted asymmetry, (2) even absence tactile input, whisker...
Natural behavior occurs in multiple sensory and motor modalities particular is dependent on feedback that constantly adjusts behavior. To investigate the underlying neuronal correlates of natural behavior, it useful to have access state-of-the-art recording equipment (e.g., 2-photon imaging, patch recordings, etc.) frequently requires head fixation. This limitation has been addressed with various approaches such as virtual reality/air ball or treadmill systems. However, achieving multimodal...
Summary Not all decisions are created equal; factors such as the difficulties or associated costs affect time spent to make decisions. This is variously interpreted speed/accuracy, fast/slow, impulsivity/deliberateness tradeoffs according different models of behaviour 1–5 . Regardless, it generally assumed that decision latency reflects neural mechanisms underlying behavioural strategy and cognitive investment. However, investigations have been difficult in mice which consistently impulsive....
Abstract A central function of the brain is to plan, predict and imagine effect movement in a dynamically changing environment. Here we show that mice head fixed plus-maze, floating on air, trained pick lanes based visual stimuli, asymmetric position whiskers two sides face signals whether animal moving, turning, expecting reward or licking. We 1) can decode behavioral state this asymmetry, 2) tactile input from indicates little about state, 3) nose correlates with indicating facial...