- Autism Spectrum Disorder Research
- Family and Disability Support Research
- Infant Development and Preterm Care
- Sleep and related disorders
- Child Nutrition and Feeding Issues
- Child Development and Digital Technology
- Child and Adolescent Psychosocial and Emotional Development
- Infant Health and Development
- Neuroscience of respiration and sleep
- Sleep and Wakefulness Research
- Cerebrospinal fluid and hydrocephalus
- Early Childhood Education and Development
- Genetics and Neurodevelopmental Disorders
- Language Development and Disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Human-Animal Interaction Studies
- Neonatal and fetal brain pathology
- ECG Monitoring and Analysis
- Heart Rate Variability and Autonomic Control
- Assistive Technology in Communication and Mobility
- Advanced MRI Techniques and Applications
- Virology and Viral Diseases
- Non-Invasive Vital Sign Monitoring
- Atomic and Subatomic Physics Research
- Traumatic Brain Injury and Neurovascular Disturbances
Purdue University West Lafayette
2015-2024
State Street (United States)
2015-2022
University of California, Davis
2009-2018
Marquette University
2018
Center for Neurosciences
2018
Yale University
2018
University of British Columbia
2018
University of California, San Francisco
2018
Hussman Institute for Autism
2018
University of California, Los Angeles
2018
Predictors of maternal depression trajectories were examined longitudinally in families with an infant born preterm or at a low birth weight. A total 181 mother-infant dyads enrolled the study before infant's neonatal intensive care unit (NICU) discharge. Maternal depressive symptoms assessed 5 timepoints, and contextual variables risks NICU Hierarchical linear models revealed that mothers who experienced more risk factors reported just their discharge showed less decline months immediately...
Abstract Developmental change emerges from dynamic interactions among networks of neural activity, behavior systems, and experience‐dependent processes. A developmental cascades framework captures the sequential, multilevel, cross‐domain nature human development is ideal for demonstrating how interconnected systems have far‐reaching effects in typical atypical development. Neurodevelopmental disorders represent an intriguing application this framework. Autism spectrum disorder (ASD) complex...
It is commonly believed that cerebrospinal fluid (CSF) movement facilitated by blood vessel wall movements (i.e., hemodynamic oscillations) in the brain. A coherent pattern of low frequency oscillations and CSF was recently found during non-rapid eye (NREM) sleep via functional MRI. This finding raises other fundamental questions: 1) explanation coupling between from fMRI signals; 2) existence wakefulness; 3) direction movement. In this resting state study, we proposed a mechanical model to...
Abstract The differential susceptibility to parenting model was examined in relation toddler self-regulation a prospective longitudinal study of infants born preterm or low birth weight. We followed 153 mother–infant dyads across five time points between the infant's Neonatal Intensive Care Unit stay and 24 months postterm. Assessments infant temperament, quality early interactions, contextual variables, effortful control behavior problems were conducted. Results supported dual risk models...
While previous studies suggested that regressive forms of onset were not common in autism spectrum disorder (ASD), more recent investigations suggest the rates are quite high and may be under‐reported using certain methods. The current study undertook a systematic investigation how regression differed by measurement method. Infants with ( n = 147) without family history ASD 83) seen prospectively for up to 7 visits first three years life. Reports symptom collected four measures...
Background We evaluated early pragmatic language skills in preschool‐age siblings of children with autism spectrum disorder ( ASD ), and examined correspondence between impairments general difficulties, symptomatology, clinical outcomes. Methods Participants were younger (high‐risk, n = 188) or typical development (low‐risk, 119) who part a prospective study infants at risk for ; without outcomes included analyses. Pragmatic measured via the Language Use Inventory LUI ). Results At 36...
Abstract Children born preterm are at risk for experiencing significant deleterious developmental outcomes throughout their childhood and adolescence. However, individual variation resilience hallmarks of the population. The present study examined pathways to across multiple domains (e.g., social activities, peer relations, attention-deficit/hyperactivity disorder symptomology, externalizing internalizing behavior, sleep quality) as children reached school age. also early child family...
Abstract Recent literature suggests that service dogs may be a valuable complementary intervention option for posttraumatic stress disorder (PTSD) among military veterans due to the potential influence on response dysregulation. The aim of this short-term longitudinal study was quantify impact in US with PTSD particular attention cortisol awakening response. A sub empirically evaluate physiological effects veteran partners. We conducted clinical trial (ID: NCT03245814) assessed 245...
Difficulties in communication and reciprocal social behavior are core features of autism spectrum disorders (ASD) often present, to varying degrees, other family members. This prospective longitudinal infant sibling study examines whether social-communicative members may inform which infants at increased risk for ASD developmental concerns.Two hundred seventeen families participated this study. Infant siblings were recruited from with least one older child diagnosed an (n = 135) or typically...
This longitudinal study examined predictors of rates growth in dyadic interaction quality children born preterm who did not experience significant neurological findings during neonatal intensive care unit (NICU) hospitalization. Multiple methods were used to collect data from 120 infants (48% girls, 52% boys) and their mothers. Infant heart rate variability (HRV), gestational age, health, feeding route, maternal socioeconomic (SES) risks assessed at NICU discharge (mean 36 weeks...
Abstract This study examined sleep, sleepiness, and daytime performance in 68 children with autism, 57 intellectual disability (ID), 69 typically developing preschool children. Children the autism ID groups had poorer behaviors than group also were significantly sleepier both groups. These significant differences persisted over 6 months. Actigraph-defined sleep problems did not relate to sleepiness or for group. For group, longer night awakenings lower efficiency predicted more sleepiness....
In the first year of life, ability to engage in sustained synchronous interactions develops as infants learn match social partner behaviors and sequentially regulate their response others. Difficulties developing competence these early building blocks can impact later language skills, joint attention, emotion regulation. For children at elevated risk for autism spectrum disorder (ASD), dyadic synchrony responsiveness difficulties may be indicative emerging ASD and/or developmental concerns....
Cerebrospinal fluid (CSF) movement through the pathways within central nervous system is of high significance for maintaining normal brain health and function. Low frequency hemodynamics respiration have been shown to drive CSF in humans independently. Here, we hypothesize that may be driven simultaneously (and synchrony) by both mechanisms study their independent coupled effects on using novel neck fMRI scans. Caudad at fourth ventricle major blood vessels (internal carotid arteries...