E.C. McNaughton

ORCID: 0000-0002-8937-9963
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About
Contact & Profiles
Research Areas
  • Opioid Use Disorder Treatment
  • Forensic Toxicology and Drug Analysis
  • Substance Abuse Treatment and Outcomes
  • Digital Mental Health Interventions
  • Child and Adolescent Psychosocial and Emotional Development
  • Health disparities and outcomes
  • Smoking Behavior and Cessation
  • Treatment of Major Depression
  • Pharmacovigilance and Adverse Drug Reactions
  • COVID-19 and Mental Health
  • Nutrition, Health and Food Behavior
  • Neural and Behavioral Psychology Studies
  • Anesthesia and Sedative Agents
  • Mental Health Research Topics
  • COVID-19 Pandemic Impacts
  • Poisoning and overdose treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pain Management and Opioid Use
  • Misinformation and Its Impacts
  • Attention Deficit Hyperactivity Disorder
  • Academic integrity and plagiarism

PatientsLikeMe (United States)
2018-2019

Inflexxion (United States)
2012-2017

Abuse of prescription opioid pain relievers continues to be a serious public health concern. In contrast opioids such as oxycodone or morphine, tapentadol, analgesic, has two mechanisms action: μ-opioid receptor agonism and norepinephrine reuptake inhibition. As result differences in its pharmacology, there may abuse profile. an initial step toward testing this hypothesis, we present postmarketing examination tapentadol's liability relative comparators.A sentinel sample 113,914 individuals...

10.1111/pme.12524 article EN Pain Medicine 2014-09-22

Background Loneliness is a growing area of concern, attracting attention as public health concern due to its association with variety psychological and physical problems. However, interventions targeting loneliness are less common than for other mental problems, such depression anxiety, existing focus primarily on building social skills increasing opportunities interaction despite research suggesting these techniques not the most effective. Furthermore, although there an need scalable...

10.2196/26617 article EN cc-by JMIR Mental Health 2021-01-21

Objective: To examine nonmedical use (NMU) of prescription ADHD stimulants among adults evaluated for substance abuse treatment. Method: 147,816 assessments from the National Addictions Vigilance Intervention and Prevention Program (NAVIPPRO) system (10/01/2009 through 03/31/2012) examined NMU prevalence, routes administration (ROA), diversion sources. Results: Past 30-day (1.29%) was significantly lower than that opioids (19.79%) or sedatives (10.62%). For stimulant products, Adderall 0.62,...

10.1177/1087054713493321 article EN Journal of Attention Disorders 2013-07-30

ABSTRACT Purpose The ability to track prescription opioid abusers' endorsement of compounds may be valuable in forecasting abuser's preferences. We developed a metric, referred as the Endorsement Ratio (ERo), explore feasibility quantifying sentiment expressed by abusers who post online about products. Methods Internet posts written between April 1, 2010 and March 31, 2011 related six (oxycodone ER, hydrocodone, hydromorphone, oxymorphone, morphine tramadol) were identified qualitatively...

10.1002/pds.3307 article EN Pharmacoepidemiology and Drug Safety 2012-07-09

Research on substance abusers in treatment suggests that tapentadol, a prescription analgesic, may have relatively low abuse potential. Messages posted by recreational drug online forums were examined for amount of discussion and endorsement tapentadol comparator drugs.Internet messages between January 1, 2011 September 30, 2012 seven drug-abuse web evaluated. Proportions posts unique authors discussing compared with eight compounds. Postcontent was coded to compare two comparators, one high...

10.1111/pme.12547 article EN Pain Medicine 2014-09-22

Background: Reformulating opioid analgesics to deter abuse is one approach toward improving their benefit-risk balance. To assess sentiment and attempts defeat these products among difficult-to-reach populations of prescription drug abusers, evaluation posts on Internet forums regarding reformulated may be useful. A version OxyContin (extended-release oxycodone) with physicochemical properties presented an opportunity evaluate about the reformulation in online discussions. Objective: The...

10.2196/jmir.3397 article EN cc-by Journal of Medical Internet Research 2014-05-02

Background/Objectives: Major depressive disorder (MDD) is a highly prevalent disorder, frequently diagnosed and treated in primary care setting; however, little information available about the treatment decision-making process between MDD patients their providers. A shared goal attainment approach to establishing tracking progress toward goals that are meaningful individual explored this survey study. In addition, patient perspectives on setting goals, medication selection/switching,...

10.2147/ppa.s204198 article EN cc-by-nc Patient Preference and Adherence 2019-06-01

Objective: Formulating prescription opioids to limit abuse remains a priority. OROS extended-release (ER) hydromorphone HCl (EXALGO) may have lower potential than many other opioid products. Three postmarketing studies of the relative liability ER were conducted. Methods: Estimates abuse, unadjusted, and adjusted for volume, generated comparators from Q2 2010 through 2014 high-risk, substance treatment population general using poison control center data. Comparators selected compound, market...

10.1097/ajp.0000000000000585 article EN Clinical Journal of Pain 2018-01-03

<sec> <title>BACKGROUND</title> Loneliness is a growing area of concern, attracting attention as public health concern due to its association with variety psychological and physical problems. However, interventions targeting loneliness are less common than for other mental problems, such depression anxiety, existing focus primarily on building social skills increasing opportunities interaction despite research suggesting these techniques not the most effective. Furthermore, although there an...

10.2196/preprints.26617 preprint EN other-oa 2020-12-18

Bei jedem neu zugelassenen Analgetikum muss das Potenzial für eine missbräuchliche Verwendung untersucht werden, um bei guter Analgesie Risiko einer Abhängigkeitsentwicklung zu minimieren. Daten Tapentadol, zugelassen mäßig starke und akute Schmerzen (schnell freisetzende Formulierung) chronische (retardierte stellen Butler et al. vor.

10.1055/s-0035-1556799 article DE Journal Club AINS 2015-06-22
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