Roma Mustafa

ORCID: 0000-0002-8979-9044
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About
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Research Areas
  • Plant Virus Research Studies
  • Plant and Fungal Interactions Research
  • Plant-Microbe Interactions and Immunity
  • SARS-CoV-2 and COVID-19 Research
  • Genetics, Bioinformatics, and Biomedical Research
  • Plant Disease Resistance and Genetics
  • Insect-Plant Interactions and Control
  • vaccines and immunoinformatics approaches
  • Insect Resistance and Genetics
  • CRISPR and Genetic Engineering
  • Research in Cotton Cultivation
  • Agronomic Practices and Intercropping Systems
  • Plant pathogens and resistance mechanisms
  • Plant Pathogenic Bacteria Studies
  • Immune responses and vaccinations
  • Machine Learning in Bioinformatics
  • Insect symbiosis and bacterial influences

Sardar Bahadur Khan Women's University
2022-2024

Pakistan Institute of Engineering and Applied Sciences
2018-2022

National Institute for Biotechnology and Genetic Engineering
2015-2022

Texas A&M University
2020

Plant receptor-like kinases (RLKs) are important players in response to pathogen infections. Verticillium and Fusarium wilts, caused by dahliae (Vd) oxysporum f. sp vasinfectum (Fov), respectively, among the most devastating diseases cotton (Gossypium spp). To understand these soil-borne fungal pathogens, we performed a genome-wide silico characterization functional screen of diverse RLKs for their involvement wilt diseases. We identified Gossypium hirsutum GhWAK7A, wall-associated kinase,...

10.1105/tpc.19.00950 article EN cc-by The Plant Cell 2020-10-09

Background COVID-19 and Middle East Respiratory Syndrome are two pandemic respiratory diseases caused by coronavirus species. The novel disease SARS-CoV-2 was first reported in Wuhan, Hubei Province, China, December 2019, became a within 2-3 months, affecting social economic platforms worldwide. Despite the rapid development of vaccines, there have been obstacles to their distribution, including lack fundamental resources, poor immunization, manual vaccine replication. Several variants...

10.2196/43906 article EN cc-by JMIR Bioinformatics and Biotechnology 2023-06-08

Begomoviruses interfere with host plant machinery to evade defense mechanism by interacting proteins. In the old world, this group of viruses are usually associated betasatellite that induces severe disease symptoms encoding a protein, βC1, which is pathogenicity determinant. Here, we show βC1 encoded Cotton leaf curl Multan (CLCuMB) requires Gossypium hirsutum calmodulin-like protein 11 (Gh-CML11) infect cotton. First, used in silico approach predict interaction CLCuMB-βC1 Gh-CML11. A...

10.1371/journal.pone.0225876 article EN cc-by PLoS ONE 2019-12-03

Abstract Clustered regularly interspaced palindromic repeats (CRISPR) and associated Cas9 nuclease (CRISPR-Cas9) systems provide adaptive immunity to prokaryotes against infectious phage particles that can be engineered as a genome-editing tool. Guided by an RNA strand, the class II type CRISPR-Cas9 system employed resistance plant DNA viruses. Here we describe efficient genome editing based on simultaneous targeting of highly conserved intergenic region (IR) virus Cotton leaf curl Kokhran...

10.21203/rs.3.rs-604666/v1 preprint EN cc-by Research Square (Research Square) 2021-06-16

<sec> <title>BACKGROUND</title> COVID-19 and Middle East Respiratory Syndrome are two pandemic respiratory diseases caused by coronavirus species. The novel disease SARS-CoV-2 was first reported in Wuhan, Hubei Province, China, December 2019, became a within 2-3 months, affecting social economic platforms worldwide. Despite the rapid development of vaccines, there have been obstacles to their distribution, including lack fundamental resources, poor immunization, manual vaccine replication....

10.2196/preprints.43906 preprint EN 2022-10-29
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