- Advanced Glycation End Products research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Biochemical effects in animals
- Antioxidant Activity and Oxidative Stress
- Blood Pressure and Hypertension Studies
- Vitamin C and Antioxidants Research
- Diabetes Management and Research
- Biochemical Acid Research Studies
- Nutritional Studies and Diet
- Diet, Metabolism, and Disease
- Alcohol Consumption and Health Effects
- Dialysis and Renal Disease Management
- Sodium Intake and Health
- Natural Antidiabetic Agents Studies
- Metabolomics and Mass Spectrometry Studies
- Fatty Acid Research and Health
- Hormonal Regulation and Hypertension
- Non-Invasive Vital Sign Monitoring
- Glaucoma and retinal disorders
- Epigenetics and DNA Methylation
- Medical and Biological Ozone Research
- Iron Metabolism and Disorders
- Erythropoietin and Anemia Treatment
- Gut microbiota and health
- Health Systems, Economic Evaluations, Quality of Life
ACS Medical College and Hospital
2023-2024
VA Nebraska Western Iowa Health Care System
2016
Jawaharlal Institute of Post Graduate Medical Education and Research
2005-2013
Cancer persists as a global challenge necessitating continual innovation in treatment strategies. Despite significant advancements comprehending the disease, cancer remains leading cause of mortality worldwide, exerting substantial economic burdens on healthcare systems and societies. The emergence drug resistance further complicates therapeutic efficacy, underscoring urgent need for alternative approaches. Drug repurposing, characterized by utilization existing drugs novel clinical...
We sought to evaluate oxidative stress parameters like malondialdehyde, total antioxidant status, and time, frequency domain heart rate variability indices in newly diagnosed untreated hypertension. also study the correlation between normotensive essential hypertensives. Fourteen males 36 male hypertensives were enrolled for study. Malondialdehyde, time studied hypertensive group. Malondialdehyde was significantly higher group, whereas status control SDNN, RR triangular index, RMSSD, log 10...
Abstract Background Aberrant deoxyribonucleic acid (DNA) contributes to inflammasome orchestrated progression of chronic inflammatory diseases like diabetes and periodontitis. The purpose the present study was estimate salivary levels DNA sensing inflammasomes, absent in melanoma 2 (AIM2), interferon γ inducible protein (IFI16), cytokine interleukin 18 (IL18) individuals with periodontitis, diabetes, healthy controls interpret its association periodontal diabetic parameters. Methods Salivary...
The global burden posed by cardiovascular disease due to a rising incidence of known risk factors like essential hypertension underlines an urgent need identify other potential dyslipidemia, elevated levels high-sensitivity CRP (hsCRP), Apo-B, and sialic acid in prehypertensive subjects. This study sought examine the possible alteration hsCRP, plasma protein bound acid, lipid interactions among these parameters Forty 34 normotensive male subjects were enrolled study. Lipid profile, ratios...
Although a wide number of experimental evidences are available regarding oxidant-antioxidant disturbance in hypertension, clinical data supporting it is lacking men early stages hypertension.The objective the study was to evaluate oxidative status and antioxidant activities males with stage I essential hypertension.Thirty hypertensives 21 normotensives were included study. Protein carbonyl, reduced glutathione, glutathione peroxidase, catalase fasting glucose assessed both groups.Results...
Abstract Clin Chem Lab Med 2006;44:1457–61.
Background: Glycation and lipid peroxidation are spontaneous reactions believed to contribute the pathogenesis of many clinical disorders. The purpose present study was evaluate levels peroxides glycated proteins in normotensive, non-diabetic obese Indian subjects assess possible associations between them.
Objectives: Iron deficiency anemia (IDA) is the most common nutritional among pregnant women in India. can be supplemented orally or intravenously to treat IDA. Intravenous supplementation of iron risky as there more possibility for production free circulation. The role generation radicals and thereby oxidative stress well known. present study tends evaluate antioxidant status intravenous sucrose treated women. Materials Methods: This prospective was conducted ACS Medical College Hospital,...
The aim of this study was to examine the possible alteration in levels C-reactive protein, protein-bound sialic acid, and other lipid risk factors newly diagnosed essential hypertensive subjects. In all, 56 33 normotensive male subjects were enrolled study. Lipid profile, apolipoprotein-B, acid estimated both groups. Total cholesterol, triglyceride, low-density lipoprotein—cholesterol, significantly increased patients with hypertension. Correlation analysis revealed a significant association...
Several studies have reported that insulin resistance and compensatory hyperinsulinemia often coexist with hypertension. Increased activity of glutathione peroxidase has been in patients essential Recently, overexpression also linked to the etiology resistance. The aim this study was determine possible relation between status hypertensive patients. A case–control performed on 35 30 control subjects. levels as measured by homeostasis model assessment index (HOMA-IR) were significantly...
Glycation and lipid peroxidation are two important processes known to play a key role in complications of many pathophysiological processes. Malondialdehyde (MDA) has been reported possible the genesis glycated proteins. This study was undertaken unravel association MDA with hemoglobin fructosamine prehypertensive patients. A case–control performed on 42 30 control subjects. Plasma glucose, MDA, fructosamine, were analyzed both groups. Partial correlation analysis predict independent fasting...