Xin Zhang

ORCID: 0000-0002-9085-8320
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About
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Research Areas
  • Particle physics theoretical and experimental studies
  • Quantum Chromodynamics and Particle Interactions
  • Radiomics and Machine Learning in Medical Imaging
  • High-Energy Particle Collisions Research
  • Epigenetics and DNA Methylation
  • Glaucoma and retinal disorders
  • Oral microbiology and periodontitis research
  • Lung Cancer Diagnosis and Treatment
  • Cardiac Arrhythmias and Treatments
  • Corneal Surgery and Treatments
  • Neutrino Physics Research
  • Cardiovascular Conditions and Treatments
  • Ocular Surface and Contact Lens
  • Dark Matter and Cosmic Phenomena
  • Dental Health and Care Utilization
  • Retinal Diseases and Treatments
  • Colorectal Cancer Screening and Detection
  • Retinal and Optic Conditions
  • Corneal surgery and disorders
  • Adipokines, Inflammation, and Metabolic Diseases
  • Advanced Glycation End Products research
  • Periodontal Regeneration and Treatments
  • Atomic and Subatomic Physics Research
  • Circadian rhythm and melatonin
  • Lung Cancer Research Studies

Yangpu Hospital of Tongji University
2021-2024

Chongqing Cancer Hospital
2021-2024

Chongqing University
2021-2024

Tongji University
2024

Institute of High Energy Physics
2006-2023

China International Science and Technology Cooperation
2023

Gansu University of Traditional Chinese Medicine
2023

Shaanxi Provincial People's Hospital
2022

Shanxi Medical University
2022

Central South University
2020

To develop and validate a radiomics nomogram for predicting stroke recurrence in symptomatic intracranial atherosclerotic stenosis (SICAS). The data of 156 patients with SICAS were obtained from the hospital database. Those without identified. separated into training cohort (n = 110) validation 46). Baseline clinical collected our medical records, plaque radiological features extracted vascular wall high-resolution imaging (VW-HRMRI). sequences included 3D-T1WI-VISTA, T2WI,...

10.3389/fnins.2022.851353 article EN cc-by Frontiers in Neuroscience 2022-04-12

Resveratrol is a polyphenolic phytoalexin which has the properties of anti-oxidant, anti-inflammatory and anti-fibrotic effects. The aim this study was to investigate effects resveratrol in primary human pterygium fibroblasts (HPFs) elucidate underlying mechanisms.Profibrotic activation induced by transforming growth factor-beta1 (TGF-β1). expression profibrotic markers, including type 1 collagen (COL1), α-smooth muscle actin (α-SMA), fibronectin, were detected western blot quantitative...

10.1265/ehpm.23-00020 article EN cc-by Environmental Health and Preventive Medicine 2023-01-01

Dry eye disease is the most common ocular surface globally, requiring a more effective treatment. We observed that high-fat diet induced macrophage polarization to M1 and further inflammation in meibomian lacrimal glands. A four-week treatment with melatonin (MLT) drops can regulate alleviate dry signs. To investigate therapeutic effects mechanisms of action MLT on high-fat-diet-induced mice, RAW 264.7 cells pretreated LPS and/or underwent digital RNA perturbation genes sequencing...

10.1016/j.isci.2024.110367 article EN cc-by-nc-nd iScience 2024-06-24

Laser therapy has been proven as an effective technique for managing ophthalmological disorders. To guide future research, we conducted a bibliometric analysis of laser applications in eye diseases from 1990 to 2022, aiming identify key themes and trends.

10.2147/opth.s458840 article EN cc-by-nc Clinical ophthalmology 2024-05-01

Patent ductus arteriosus (PDA) is one of the most common congenital heart diseases. Once PDA diagnosed, it needs to be dealt with in time. At present, main methods include pharmacological treatment, surgical closure, and interventional closure for treatment PDA. However, effect different interventions management still controversial. Thus, our study aims assess effectiveness together estimate sequence these therapies children. Meanwhile, necessary conduct a Bayesian network meta-analysis...

10.1186/s13643-023-02195-4 article EN cc-by Systematic Reviews 2023-03-02

Abstract Purpose Pathogenesis and the associated risk factors of cataracts, glaucoma, age-related macular degeneration (AMD) remain unclear. We aimed to investigate causal relationships between circulating cytokine levels development these diseases. Patients methods Genetic instrumental variables for cytokines were derived from a genome-wide association study 8293 European participants. Summary-level data AMD, senile cataract obtained FinnGen database. The inverse variance weighted (IVW) was...

10.1093/hmg/ddae041 article EN Human Molecular Genetics 2024-04-23

Abstract Background: Mechanical plaque removal has been commonly accepted to be the basis for periodontal treatment. This study aims compare effectiveness of ultrasonic and manual subgingival scaling at different initial probing pocket depths (PPD) in Methods: English-language databases (PubMed, Cochrane Central Register Controlled Trials, EMBASE, Medline, ClinicalTrials.gov, by January, 2019) were searched. Weighted mean differences primary outcomes, PPD clinical attachment loss (CAL)...

10.21203/rs.2.13066/v4 preprint EN cc-by Research Square (Research Square) 2020-03-18

We aim to analyze the characteristics of stereotactic radiotherapy trials registered on ClinicalTrials.gov, and compare completed stopped early identify predictors trial failure.All interventional ClinicalTrials.gov before Dec 31, 2019 were downloaded. Trial over time between different regions compared by Chi-square test. Binary logistic regression was used explore associated with early.A total 760 included. A higher proportion about lung cancer (20.4%), prostate (14.7%) central nervous...

10.21037/tcr-21-1189 article EN Translational Cancer Research 2021-10-01

Abstract Background Laser therapy has been proven as an effective technique for managing ophthalmological disorders. To guide future research, we conducted a bibliometric analysis of laser applications in eye diseases from 1990 to 2022, aiming identify key themes and trends. Methods retrieved 3027 publications the Web Science Core Collection (WoSCC). Bibliometrix was used science mapping literature, while VOSviewer CiteSpace were applied visualize co-authorship, co-citation, co-occurrence,...

10.21203/rs.3.rs-3489186/v1 preprint EN cc-by Research Square (Research Square) 2023-10-28
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