Introduction Overdiagnosis in PSA-based prostate cancer (PCa) screening is primarily studied younger, healthier populations from clinical trials. This study aimed to evaluate the probability of overdiagnosis PCa within a practice context, focusing on its relationship with PSA levels, Gleason scores, and subsequent procedures. Methods We conducted retrospective cohort analysis 1,070 asymptomatic men over 40 years old diagnosed between 2004 2022, following positive test. The patients were...

Our aim was to explore patients' perceptions of changes in diet and physical activity people with type 2 diabetes mellitus and/or arterial hypertension two low-income districts Ecuador. We carried out a qualitative study 19 telephone interviews August-September 2020 hypertension. Interviews were recorded, anonymized transcribed verbatim for analysis using the social ecological model. Within context poor access health services, participants identified lack policies address food insecurity...

Abstract Background Type 2 diabetes mellitus (T2DM) is a pressing public health challenge in Latin America, with an increasing prevalence and negative impacts on population health. Achieving optimal blood glucose levels critical for preventing complications, yet significant socioeconomic inequities persist disease management control. We aimed to investigate the patient characteristics associated fasting capillary individuals living T2DM hard-to-reach setting Esmeraldas, Ecuador. Methods...

Abstract Promoting healthy behaviours to improve population health requires strategies that foster supportive environments and actively engage communities. Here, we detail an evidence-informed co-creation process in Ferroviaria, a low-income neighbourhood Quito, Ecuador, led by six members of local Women’s Association. Co-creation here involved participatory approach integrated epidemiological data on non-communicable disease (NCD) risk factors employed the "Dialogue Forum" methodology guide...

Recognizing the need for a consensus tool to measure social class in health sciences, 1995 Spanish Society of Epidemiology (Sociedad Española de Epidemiología [SEE]) made proposal such measure. The aim this article was explore bibliometric impact SEE's proposal.Articles citing report and those articles published as result were identified using Google Scholar Scopus. information extracted from these consisted year, nationality factor journal, self-citation, source, subject area, city first...

Abstract Background Type 2 Diabetes (T2DM) prevalence is increasing in low- and middle-income countries along with high levels of obesity which vary according to socioeconomic contextual characteristics. We aim estimate the T2DM men women a hard-to-reach rural area northern Ecuador considering socio-demographic Methods Cross-sectional descriptive study based on population-based survey Eloy Alfaro health district Esmeraldas between October 2020 January 2022. collected sociodemographic...

It is well known that sex differences in analgesic prescription are not merely the logical result of greater prevalence pain women, since this therapeutic variability related to factors such as educational level or social class. This study aims analyse relationship between and gender development different regions Spain. Cross-sectional sex-differences according studied. Analgesic prescription, demographic variables were obtained from Spanish Health Interview Survey 2006. Gender was measured...

Este estudio tiene como objetivo analizar las relaciones entre actitudes sexistas, los pensamientos distorsionados sobre la mujer y el uso de violencia comportamientos con pareja, en universitarios ecuatorianos ramas relacionas bienestar salud. La muestra está conformada por 646 alumnos tres universidades (424 alumnas 222 alumnos). Se aplicaron siguientes instrumentos: Versión modificada Escala Tácticas para Conflictos, Inventario Sexismo Ambivalente, Pensamientos Distorsionados Deseabilidad...

The purpose of this quasi-experimental study was to assess levels compliance with the intervention bundles contained in a clinical pathway used treatment patients severe sepsis and septic shock, analyze pathway's impact on survival duration hospital stays. We data 125 an Intensive Care Unit, divided into control group (N=84) (N=41). Levels increased from 13.1% 29.3% 5 resuscitation bundle interventions 14.3% 22% 3 monitoring interventions. In-hospital mortality at 28 days decreased by 11.2%...

Despite considerable research investment, moving from biomarker discovery to clinical application has presented unique challenges. We aimed evaluate progress toward of a sample molecular- and "omics"-based diagnostic tests over 10-year period.We used Scopus locate studies, published before the December 31, 2016, citing 107 original-research articles in 2006 that assessed value or test. identified studies same test disease determined whether article represented validation molecular classified...

Objectives To determine the factors associated with lung cancer diagnosis and mortality after detecting a solitary pulmonary nodule (SPN) in routine clinical practice, men women for both chest radiograph CT. Materials methods A 5-year follow-up of retrospective cohort 25,422 (12,594 men, 12,827 women) patients aged ≥35 years referred or CT two hospitals Spain (2010–2011). SPN were detected 893 (546 347 patients. We estimated cumulative incidence at 5-years, association patient...

The balance of the benefits and risks long term use hormone replacement therapy (HRT) have been a matter debate for decades. In Europe, HRT requires medical prescription its advertising is only permitted when aimed at health professionals (direct to consumer allowed in some non European countries). objective this study analyse appropriateness quality Internet about Spain. A search was carried out on (January 2009) using eight best-selling drugs brand name each drug entered into Google's...

It has been shown that gender equity a positive impact on the everyday activities of people (decision making, income allocation, application and observance norms/rules) which affect their health. Gender is also crucial determinant health inequalities at national level; thus, monitoring important for surveillance women’s men’s as well future policy initiatives. The Equity Index (GEI) was designed to show inequity solely towards women. Given value under scrutiny equity, in this paper modified...

La introducción de la vacuna contra el virus del papiloma humano (VPH) dirigida a mujeres adolescentes ha tenido en España un desarrollo no exento cierta controversia. Asociada inicialmente al mensaje «vacuna cáncer útero» que ofrecía una nueva posibilidad lucha esa enfermedad, obtuvo réplica moderaba euforia con dirigido probar evidencias. Mientras se administraba segunda dosis (febrero 2009) ocurrió suceso inesperado Valencia relacionado aparición acontecimientos adversos tras...