A5013641148- Microbial metabolism and enzyme function
- Biofuel production and bioconversion
- Medicinal Plant Research
- Enzyme Production and Characterization
- RNA Interference and Gene Delivery
- Algal biology and biofuel production
- Enzyme Catalysis and Immobilization
- Probiotics and Fermented Foods
- Food and Agricultural Sciences
- Porphyrin Metabolism and Disorders
- SMEs Development and Digital Marketing
- Protein Hydrolysis and Bioactive Peptides
- Advanced biosensing and bioanalysis techniques
- Genetics, Bioinformatics, and Biomedical Research
- Enzyme function and inhibition
- DNA and Nucleic Acid Chemistry
- Metal-Catalyzed Oxygenation Mechanisms
- Biocrusts and Microbial Ecology
- Agricultural and Biological Research
- Molecular Biology Techniques and Applications
- Antimicrobial Peptides and Activities
- Enzyme Structure and Function
- Financial Literacy and Behavior
- MicroRNA in disease regulation
- Food Allergy and Anaphylaxis Research
Indonesia Defense University
2021-2024
Regional Development Agency
2020
Universitas Samawa
2019-2020
Universitas Nusa Tenggara Barat
2018
University of Indonesia
2017
Indonesian Institute of Sciences
2006-2015
Dharmais Cancer Hospital
2014-2015
IPB University
2015
Pusat Penelitian dan Pengembangan Peternakan
2010
Tokyo University of Agriculture and Technology
1994-2001
The biological mechanisms that underpin primate social evolution remain poorly understood. Asian colobines display a range of organizations, which makes them good models for investigating evolution. By integrating ecological, geological, fossil, behavioral, and genomic analyses, we found colobine primates inhabit colder environments tend to live in larger, more complex groups. Specifically, glacial periods during the past 6 million years promoted selection genes involved cold-related energy...
Chitosan-based particles are desirable materials for drug delivery because of their muco-adhesiveness in tissues, biocompatibility, low toxicity and effectiveness antigen transport. It is still a challenge to prepare chitosan-based with high stability by an effective method. Here we developed nanoparticles the toll-like receptor 9 ligands, cytosine-phosphate-guanine oligodeoxynucleotides (CpG ODNs), which can induce change from Th-2 type Th-1 immune response. Because tolerance DNase less...
The aim of this study was to evaluate the effectiveness probiotics Lactobacillus plantarum 2C12 and acidophilus 2B4 prevent diarrhea caused by enteropathogenic Escherichia coli (EPEC). Albino rats (Rattus norvegicus) were daily orally administered 108 cfu/ml both without or simultaneously infected with EPEC (106 cfu/ml) for 7 days. Negative control not probiotic while positive challenged alone. After 1, 2 3 weeks, total lactic acid bacteria (LAB) E. mucosa cecum content evaluated. It...
Cardiopulmonary bypass during tetralogy of Fallot corrective surgery is associated with oxidative stress, and contributes to peri-operative problems. Curcumin has been known as a potent scavenger reactive oxygen species, which enhances the activity antioxidants suppresses phosphorylation transcription factors involved in inflamation apoptosis.To evaluate effects curcumin an antioxidant by evaluating concentrations malondialdehyde glutathione, nuclear factor-kappa B, c-Jun N-terminal kinase,...
An engineered Escherichia coli PQQ glucose dehydrogenase (PQQGDH) with improved enzymatic characteristics was constructed by substituting and combining the gene-encoding protein regions responsible for EDTA tolerance, thermal stability substrate specificity. The region complete tolerance in Acinetobacter calcoaceticus, which is recognized as indicator of high co-factor binding, elucidated. located between 32 59% from N-terminus A. calcoaceticus PQQGDH(A27 region) also corresponds to same...
To reduce the level of CO2 content in air, effort on converting to useful products is required. One alternatives includes fixation produce biomass using Chlorella vulgaris Buitenzorg. Buitenzorg applied for production food supplement. also easy handle due its superior adaptation. Currently, has been analyzed by some experts cellular composition, ability high quality and essential nutrition. A series experiments was conducted culturing Beneck medium bubbling column photobioreactor. The main...
This study investigated the efficacy of tannin in order to control leaf blight disease on Toona sureni caused by Rhizoctonia sp. measuring intensity and percentage damages.Two sp.(R1 R2) isolates were induced T. leaves.Tannin solution with concentration 0.5, 1, 2 3% (water) sprayed leaves surface every two days.The sign was measured days for one month.Results revealed that all treatments reduced death percentage.No poisonous impacts seedling observed.The highest concentrations which reduce...
Normal 0 false IN X-NONE MicrosoftInternetExplorer4 The precursors, Na 2 HPO 4 .2H O and CaCl are used for synthesizing pure hydroxyapatite which less of carbonate content. high temperature sintering, about 700 o C temperature, is treated to minimize the group on surface. Carbonate content sintered in than 110 C. It indicates an increasing sintering will increase crystallinity decrease hydroxapatite. This method gave better way resulting crystal. patterns band SDS PAGE Protein Purification...
In this paper, a novel electron mediator, 1-methoxy-5-ethyl phenazinium ethyl sulfate (mPES), was introduced as versatile mediator for disposable enzyme sensor strips, employing representative flavin oxidoreductases, lactate oxidase (LOx), glucose dehydrogenase (GDH), and fructosyl peptide (FPOx). A with oxygen insensitive Aerococcus viridans-derived engineered LOx (AvLOx), A96L mutant the enzyme, constructed. The constructed exhibited high sensitivity (0.73 ± 0.12 μA/mM) wide linear range...
This study aims to prepare high stability chitosan nanoparticles (CNP) and examine the ability of CNP in CpG-ODN delivery when treating allergic mice model.Preparation characterization were performed by ionic gelation, dynamic light scattering, zeta sizer. The cytotoxicity activation CpG ODN delivered with tested using a cell counting kit-8 Quanti blue method. Allergic injected intraperitoneal 10 ug ovalbumin on day 0 7, then treated intranasal ODN/CpG ODN, CNP/CNP, third week three times...
Protein engineering of the beta-propeller protein aimed at enhancing structural stability was carried out using a monomeric single domain protein, Salmonella typhimurium sialidase, as model. Ala53 and Ala69 each located strands B C W1 motif were mutated to Leu Val, respectively, increase hydrophobic interaction between W6 motifs. The mutants showed enhanced towards guanidine hydrochloride thermal unfolding. Ala53Leu higher stability, probably owing capability interact extensively with more...
Guanine-quadruplex-based CpG oligodeoxynucleotides (G4 ODNs) have been developed as potent immunostimulatory agents with reduced sensitivity to nucleases. We designed new monomeric G4 ODNs an antiparallel topology using type duplex/G4 robust scaffolds, and we characterized their effects on cytokine secretion. Based circular dichroism analysis quantification of mRNA levels cytokines, it was found that containing two motifs in the first functional loop, named G2.0.0, could maintain generate a...