- Blood Coagulation and Thrombosis Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Kidney Injury Research
- Aortic aneurysm repair treatments
- Receptor Mechanisms and Signaling
- Bariatric Surgery and Outcomes
- Biochemical and Structural Characterization
- Diet and metabolism studies
- Renin-Angiotensin System Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tracheal and airway disorders
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cell Adhesion Molecules Research
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Neuropeptides and Animal Physiology
- Respiratory viral infections research
Western University
2018-2021
Objetivo: Analisar revisões sistemáticas sobre Critérios Diagnósticos Para Bronquiolite Viral Aguda Na Infância, com foco no diagnóstico clínico e complementares, assim como as dificuldades encontradas pelos profissionais da área saúde para o seu diagnóstico. Métodos: análise bibliográfica, do tipo revisão integrativa literatura, que foi realizado a partir de artigos publicados em perfil eletrônicos durante período 2018 à 2024. As variáveis estudadas foram: autor, ano, país critério...
Proteinase-activated receptor 4 (PAR4) is a member of the proteolytically-activated PAR family G-Protein Coupled Receptors. PARs are activated following proteolytic cleavage N-terminus by enzymes such as thrombin, trypsin, and Cathepsin-G to reveal activating motif termed tethered ligand. The ligand binds intramolecularly trigger signaling trafficking cascades. can also be short synthetic peptides derived from sequence.
Abstract Proteinase Activated Receptor-4 (PAR4) is a member of the proteolytically-activated PAR family G-Protein-coupled Receptors (GPCRs). PARs are activated following proteolytic cleavage receptor N-terminus by enzymes such as thrombin, trypsin, and cathepsin-G to reveal receptor-activating motif termed tethered ligand. The ligand binds intramolecularly triggers signalling cellular responses. In spite this unusual mechanism activation, fundamentally peptide receptors can also be exogenous...