A5040205182- Reproductive Health and Contraception
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and fetal healthcare
- Blood Coagulation and Thrombosis Mechanisms
- Endometriosis Research and Treatment
- Venous Thromboembolism Diagnosis and Management
- Prenatal Screening and Diagnostics
- Ovarian cancer diagnosis and treatment
- Cardiovascular Issues in Pregnancy
- Neurological Complications and Syndromes
- Ectopic Pregnancy Diagnosis and Management
- Maternal and Perinatal Health Interventions
- Maternal Mental Health During Pregnancy and Postpartum
- Reproductive System and Pregnancy
- Pregnancy and preeclampsia studies
- Endometrial and Cervical Cancer Treatments
- Cancer Risks and Factors
- Ovarian function and disorders
- Reproductive Health and Technologies
- Birth, Development, and Health
- Estrogen and related hormone effects
- Global Maternal and Child Health
- Pregnancy and Medication Impact
- Child and Adolescent Health
- Reproductive Biology and Fertility
University of Copenhagen
2015-2024
Rigshospitalet
2015-2024
Copenhagen University Hospital
2013-2024
Gentofte Hospital
1984-2024
Capital Region of Denmark
2009-2017
Peking University
2017
Weatherford College
1998-2011
Amsterdam UMC Location University of Amsterdam
2011
Roskilde Sygehus
2010
Danish Cancer Society
2009
To assess the risk of venous thromboembolism from use combined oral contraceptives according to progestogen type and oestrogen dose.National historical registry based cohort study.Four registries in Denmark.Non-pregnant Danish women aged 15-49 with no history thrombotic disease followed January 2001 December 2009.Relative absolute risks first time thromboembolism.Within 8,010,290 years observation, 4307 ever thromboembolic events were recorded 4246 included, among which 2847 (67%) confirmed...
Although several studies have assessed the risk of venous thromboembolism with newer hormonal contraception, few examined thrombotic stroke and myocardial infarction, results been conflicting.In this 15-year Danish historical cohort study, we followed nonpregnant women, 15 to 49 years old, no history cardiovascular disease or cancer. Data on use clinical end points, potential confounders were obtained from four national registries.A total 1,626,158 women contributed 14,251,063 person-years...
Millions of women worldwide use hormonal contraception. Despite the clinical evidence an influence contraception on some women's mood, associations between and mood disturbances remain inadequately addressed.To investigate whether is positively associated with subsequent antidepressants a diagnosis depression at psychiatric hospital.This nationwide prospective cohort study combined data from National Prescription Register Psychiatric Central Research in Denmark. All adolescents aged 15 to 34...
Little is known about whether contemporary hormonal contraception associated with an increased risk of breast cancer.We assessed associations between the use and invasive cancer in a nationwide prospective cohort study involving all women Denmark 15 49 years age who had not or venous thromboembolism received treatment for infertility. Nationwide registries provided individually updated information contraception, breast-cancer diagnoses, potential confounders.Among 1.8 million were followed...
Abstract Objective To assess rates of cardiovascular and haemostatic events in the first 28 days after vaccination with Oxford-AstraZeneca vaccine ChAdOx1-S Denmark Norway to compare them observed general populations. Design Population based cohort study. Setting Nationwide healthcare registers Norway. Participants All people aged 18-65 years who received a from 9 February 2021 11 March 2021. The populations (2016-18) (2018-19) served as comparator cohorts. Main outcome measures Observed day...
<b>Objective</b> To assess the risk of venous thrombosis in current users non-oral hormonal contraception. <b>Design</b> Historical national registry based cohort study. <b>Setting</b> Four registries Denmark. <b>Participants</b> All Danish non-pregnant women aged 15-49 (n=1 626 158), free previous thrombotic disease or cancer, were followed from 2001 to 2010. <b>Main outcome measures</b> Incidence rate transdermal, vaginal, intrauterine, subcutaneous contraception, relative compared with...
Several studies published in the past 10 years have evaluated risk of venous thromboembolic complications with use newer hormonal contraceptives, but few examined thrombotic stroke and myocardial infarction. Results available been conflicting. The aim Danish historical cohort study was to assess risks infarction among women who received various types contraception. Over a 15-year period (1995–2009), data were obtained on contraception, clinical end points, potential confounders from national...
The aim of this study was to compare the frequency imprinting diseases in children born after IVF with incidence naturally conceived children.All singleton Denmark from January 1, 1995 through December 31, 2001 were stratified into without and IVF, followed birth until end 2002 National Register Patients Central Psychiatric Diseases, which include all discharge diagnoses somatic psychiatric hospitals/clinics, respectively. Included malignancies, mental, behavioural neurological diseases,...
To assess the fetal loss rate following amniocentesis and chorionic villus sampling (CVS).This was a national registry-based cohort study, including all singleton pregnant women who had an (n = 32 852) or CVS 31 355) in Denmark between 1996 2006. Personal registration numbers of having were retrieved from Danish Central Cytogenetic Registry, cross-linked with National Registry Patients to determine outcome each pregnancy. Postprocedural defined as miscarriage intrauterine demise before 24...
The purpose of this study was to assess the effect a vanishing twin on risk being small-for-gestational age (SGA) in vitro fertilization (IVF) singletons. included 642 survivors vanished co-twin, 5237 primary singletons and 3678 twins. survivor cohort subdivided according gestational at time give groups early (<8 weeks), intermediate (8–22 weeks) late (>22 survivors. rate SGA infants significantly higher than (OR: 1.50, 95%CI: 1.03–2.20) significant inverse correlation observed between (r =...
Concern has been expressed about potential harm to women's mental health in association with having an induced abortion, but it remains unclear whether abortion is associated increased risk of subsequent psychiatric problems.We conducted a population-based cohort study that involved linking information from the Danish Civil Registration system Psychiatric Central Register and National Patients. The consisted data for girls women no record disorders during 1995-2007 period who had...
Objective: The purpose of this study was to assess the relative risk suicide attempt and in users hormonal contraception. Method: authors assessed associations between contraceptive use a nationwide prospective cohort all women Denmark who had no psychiatric diagnoses, antidepressant use, or before age 15 turned during period, which extended from 1996 through 2013. Nationwide registers provided individually updated information about contraception, attempt, suicide, potential confounding...
Several data indicate that migraine, especially migraine with aura, is associated an increased risk of ischemic stroke and other vascular events. Of concern whether the in migraineurs magnified by use hormonal contraceptives. As prevalence high women reproductive age, it common to face issue contraceptive clinical practice. In this document, we systematically reviewed about association between use. Thereafter a consensus procedure among international experts was done develop statements...
To establish a method of estimating the proportion women with subsequent live birth after well-defined time period in an open cohort referred to tertiary recurrent miscarriage clinic.We performed descriptive study register-based follow-up at center for investigation and treatment Denmark. All primary or secondary clinic from 1986 2008 were included (n=987). Main outcome measures age-specific miscarriage-specific proportions first consultation similar hazard ratios compared prognosis aged...
The objective of this study was to assess obstetrical complications and neonatal outcomes in women with endometriosis as compared without endometriosis.National cohort including all delivering their newborns Denmark 1997-2014. Data were extracted from the Danish Health Register Medical Birth Register. Logistic regression analysis provided odds ratios (OR) 95% confidence intervals (CI). Sub-analyses made for primiparous a singleton pregnancy who underwent gynecological surgery before...
The aim was to compare contraceptive use in the Nordic countries and assess compliance with recommendations from European Medicines Agency regarding of combined oral contraception containing low-dose estrogen levonorgestrel, norethisterone or norgestimate.Data on hormonal prescriptions sales figures for copper intrauterine devices were obtained national databases manufacturers Denmark, Finland, Iceland, Norway Sweden 2010-2013.Contraceptive highest Denmark (42%) (41%), followed by Finland...
Objective To quantify risk factors for venous thromboembolism during pregnancy and the puerperal period. Design In a nationwide prospective cohort study we followed pregnant women in Denmark from 1995 to 2009 thromboembolism. Information on confounders was retrieved national registries. The diagnosis of confirmed through medical charts. We calculated adjusted incidence rates per 10,000 years used Poisson regression estimate effects Results studied 1,297,037 pregnancies related periods, which...
Has the perinatal outcome of children conceived after assisted reproductive technology (ART) improved over time?The outcomes in born ART have last 20 years, mainly due to reduction multiple births.A Swedish study has shown a unwanted time ART. Our analyses based on data from more than 92 000 four Nordic countries confirm these findings.Nordic population-based matched cohort with and health Denmark, Finland, Norway Sweden.We analysed 62 379 singletons 29 758 twins, 1988 2007 countries. The...
To investigate the association between contemporary combined hormonal contraceptives (including progestogen types in preparations and all progestogen-only products) overall specific of ovarian cancer.Prospective, nationwide cohort study.Denmark, 1995-2014.All women aged 15-49 years during 1995-2014 were eligible. Women excluded if they immigrated after 1995, had cancer (except non-melanoma skin cancer), venous thrombosis, or treated for infertility before entry (final study population...
<h3>Abstract</h3> <b>Objectives:</b>To determine the association between myocardial infarction and use of different types oral contraception in young women. <b>Design:</b>Community based case-control study. Data from interviews general practice records. <b>Setting:</b>England, Scotland, Wales. <b>Participants:</b>Cases (n=448) were recruited women aged 16 44 who had suffered an incident 1 October 1993 1995. Controls (n=1728) without a diagnosis matched for age practice. <b>Main outcome...