A5101473249- Welding Techniques and Residual Stresses
- Prenatal Screening and Diagnostics
- Advanced Welding Techniques Analysis
- Genomic variations and chromosomal abnormalities
- Mechanical Engineering and Vibrations Research
- Structural Integrity and Reliability Analysis
- Hydraulic and Pneumatic Systems
- Engineering Applied Research
- Non-Destructive Testing Techniques
- Selenium in Biological Systems
- Manufacturing Process and Optimization
- Mechanical Behavior of Composites
- Metal Forming Simulation Techniques
- Cardiovascular Health and Risk Factors
- Industrial Technology and Control Systems
- Structural Analysis of Composite Materials
- Laser and Thermal Forming Techniques
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Fetal and Pediatric Neurological Disorders
- Genomics and Rare Diseases
- Metallurgy and Material Forming
- Mycobacterium research and diagnosis
- Demographic Trends and Gender Preferences
- HIV, Drug Use, Sexual Risk
Guangzhou Medical University
2013-2024
Guangzhou Women and Children Medical Center
2013-2022
Fudan University
2020
Jilin University
2019
University of Southern California
2008-2018
Peking University Third Hospital
2015
Peking University
2015
Marine design (Norway)
2012
Edison Welding Institute
2008-2009
Nanjing Boiler and Pressure Vessel Inspection Institute
2007
Abstract Analyses of cell-free fetal DNA (cff-DNA) from maternal plasma using massively parallel sequencing enable the noninvasive detection feto-placental chromosome aneuploidy; this technique has been widely used in clinics worldwide. Noninvasive prenatal tests (NIPT) based on cff-DNA have achieved very high accuracy; however, they suffer copy-number variations (CNV) that may cause false positives and negatives. In study, we developed an algorithm to exclude effect CNV refined Z-score is...
Background: Inherited factors and maternal behaviors are thought to play an important role in the etiology of several congenital malformations. Twin studies can offer additional evidence regarding contribution genetic lifestyle common birth anomalies, but few large-scale have been reported.
Abstract Cam-lobe radial-piston hydraulic motors are widely used as rotation driving units for various marine machinery owing to their ultrahigh output torque (more than 100 kN m). A multi-row cam roller bearing (MCRB) is the key component that directly determines fatigue life of a cam-lobe motor. However, compact geometry and complex loads render MCRB susceptible failure, highlighting need an optimized achieve longer higher reliability. Therefore, this study proposes innovative optimization...
We present prenatal diagnosis and chromosomal microarray analysis (CMA) of 9q34.3 microdeletion in a foetus with an increased nuchal translucency (NT). Conventional G-banding showed de novo translocation: 45, XX, dic (9;13)(q34;p13). CMA revealed 3.6 Mb encompassing OMIM gene EHMT1 consistent the Kleefstra syndrome 9q subtelomeric deletion syndrome. suggest application at pregnancies NT apparent balanced translocation on conventional karyotype.
Objectives Our objective was to determine the impact of maternal HIV–hepatitis B virus (HBV) coinfection on pregnancy outcomes. Methods The current study conducted in a county Yi Autonomous Prefecture southwest China. Data were abstracted from hospitalisation records, including and infant information. seroprevalences HIV HBV infections HIV–HBV determined adverse outcomes assessed using logistic regression analysis. A treatment effects linear model also applied examine effect HBV, or quantify...
This paper describes a straightforward method for the design and certification of adhesively bonded composite to steel joints marine industry. Normally, is based on documented service at sea. Since these have not been previously deployed sea, no data their performance exist. Using an integrated combination mechanical property evaluation finite element modeling, load- bearing capacity joint can be compared with anticipated seaway loads. Calculated factors safety sandwich used here show that...
A lump-pass welding simulation technology was developed for shipbuilding and ship repair applications based on Battelle Caterpillar VFT™ weld modeling software. To develop this technology, we reanalyzed a 3D multi-pass model that originally used in the NIST project where developed. In model, good agreement achieved between moving arc experimental data. By reanalyzing using heat input calculation method further establish efficiency of performed analyses structural configuration common to...
Trisomy 18p is a rarely observed chromosomal aberration. Only 31 cases have previously been described in the literature. associated with mild to moderate phenotypic anomalies and intellectual disability. Here, we report on pregnant woman whom noninvasive prenatal testing indicated high risk of fetal trisomy 18. Prenatal diagnosis karyotyping parents were performed demonstrated that both mother fetus had derivative chromosome 15 segment unknown origin. Chromosomal microarray analysis FISH...
Virtual fabrication technology (VFT) weld modeling software has been mainly used in thick-structure welding simulation. Recently both U. S. and European shipyards have shown strong interests using the to predict control distortion of thin-plate ship panels. It is more complicated simulate thin structures than thick because buckling often occurs during structures. To evaluate effectiveness VFT for predicting structures, a bead-on-plate specimen, butt joint two large plates, long T stiffener...
Weld modeling technology and control mitigation techniques of residual stress distortion have made a significant progress in the past decade. Q-Weld as latest development weld technique can provide solution an extremely short time compared to traditional thermo-elastic-plastic analysis. Three techniques, transient thermal tensioning, low non-distortion in-process rolling, are discussed this paper.
Abstract Background Carriers of reciprocal translocations often have more unbalanced spermatozoa and higher DNA fragmentation rates, elevating reproductive risk. The simple swim‐up method (SSUM) can decrease the amount with abnormal chromatin structure fragmented DNA, however, it has limited efficacy in eliminating chromosomally sperm. Methods eight Robertsonian translocation (Rob) carriers were split into three groups: original raw semen group (control group); SSUM swimming trapper (STM)...
A virtual fabrication technology (VFT) is introduced in this paper. It a state-of-the-art cutting and welding simulation tool developed by Battelle Caterpillar the past few years. can model extremely large complicated structure fabrications. Extensive full-scale experiments have validated accuracy predictive power. be used to reduce cost improve quality minimizing controlling distortions. Two application examples are presented illustrate how apply welded design manufacture.
We describe five Chinese individuals carrying a codon 30 (–GAG) (α2) (HBA2: c.91_93del) mutation, including three heterozygotes and two patients with Hb H (β4) disease. The presented hematological parameters of microcytosis hypochromia. disease were transfusion-independent had survived to adulthood. Screening for this nondeletional allele, correlation genotype phenotype in is important genetic counseling.