Guillaume Sanchez

ORCID: 0000-0002-9191-4259
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About
Contact & Profiles
Research Areas
  • Geology and Paleoclimatology Research
  • RNA modifications and cancer
  • Geological and Geochemical Analysis
  • earthquake and tectonic studies
  • Landslides and related hazards
  • RNA and protein synthesis mechanisms
  • Peptidase Inhibition and Analysis
  • Geological and Geophysical Studies Worldwide
  • Geological Modeling and Analysis
  • Geological formations and processes
  • Hydrocarbon exploration and reservoir analysis
  • RNA Interference and Gene Delivery
  • Geological Studies and Exploration
  • Geological and Geophysical Studies
  • Geochemistry and Geologic Mapping
  • Cryospheric studies and observations
  • Polar Research and Ecology
  • Sustainable Agricultural Systems Analysis
  • Environmental and Ecological Studies
  • Infective Endocarditis Diagnosis and Management
  • Video Analysis and Summarization
  • Geological Formations and Processes Exploration
  • Aeolian processes and effects
  • Paleontology and Stratigraphy of Fossils
  • Cancer therapeutics and mechanisms

Inserm
2024-2025

Université de Lorraine
2024-2025

Centre National de la Recherche Scientifique
2006-2025

University of Tasmania
2021

Geoscience Australia
2018-2021

ACT Government
2015

Université Côte d'Azur
2009-2014

Observatoire de la Côte d’Azur
2011-2014

Institut de Recherche pour le Développement
2009-2014

Géoazur
2009-2012

Natural transformation is a widespread mechanism for genetic exchange in bacteria. Aminoglycoside and fluoroquinolone antibiotics, as well mitomycin C, DNA-damaging agent, induced Streptococcus pneumoniae. This induction required an intact competence regulatory cascade. Furthermore, C of recA was strictly dependent on the development competence. In response to antibiotic stress, S. pneumoniae, which lacks SOS-like system, exhibited transformation. The design antibiotherapy should take into...

10.1126/science.1127912 article EN Science 2006-07-06

Tgt is the enzyme modifying guanine (G) in tRNAs with GUN anticodon to queuosine (Q). tgt required for optimal growth of Vibrio cholerae presence sub-lethal aminoglycoside concentrations. We further explored here role Q34 efficiency codon decoding upon tobramycin exposure. characterized its impact on overall bacterial proteome, and elucidated molecular mechanisms underlying effects modification antibiotic translational stress response. Using reporters, we showed that impacts at tyrosine TAT...

10.7554/elife.96317.3 article EN cc-by eLife 2025-01-06

Terra Nova, 23, 116–126, 2011 Abstract New apatite fission track (AFT) and (U‐Th)/He ages from the Argentera–Mercantour External Crystalline Massif of SW Alps document an exhumation history along transcurrent dextral faults. Significant AFT age differences across strikes main faults have been obtained NE (12.9 Ma) to (5.2 are linked vertical uplifts these right‐lateral transpressional structures. Such segmentation is not observed in AHe ages. preserved younger (4–5 on eastern hangingwall...

10.1111/j.1365-3121.2011.00991.x article EN Terra Nova 2011-02-24

Abstract We present PetroChron Antarctica, a new relational database including petrological, geochemical and geochronological data sets along with computed rock properties from geological samples across Antarctica. The contains whole‐rock geochemistry major/trace element isotope analyses, geochronology multiple isotopic systems minerals for given samples, as well an internally consistent classification based on chemical analysis derived (i.e., indices, density, p ‐velocity, heat production)....

10.1029/2021gc010154 article EN Geochemistry Geophysics Geosystems 2021-12-01

Tgt is the enzyme modifying guanine (G) in tRNAs with GUN anticodon to queuosine (Q). tgt required for optimal growth of Vibrio cholerae presence sub-lethal aminoglycoside concentrations. We further explored here role Q34 efficiency codon decoding upon tobramycin exposure. characterized its impact on overall bacterial proteome, and elucidated molecular mechanisms underlying effects modification antibiotic translational stress response. Using reporters, we showed that impacts at tyrosine TAT...

10.7554/elife.96317 article EN cc-by eLife 2024-06-05

Tgt is the enzyme modifying guanine (G) in tRNAs with GUN anticodon to queuosine (Q). tgt required for optimal growth of Vibrio cholerae presence sub-lethal aminoglycoside concentrations. We further explored here role Q34 efficiency codon decoding upon tobramycin exposure. characterized its impact on overall bacterial proteome, and elucidated molecular mechanisms underlying effects modification antibiotic translational stress response. Using reporters, we showed that impacts at tyrosine TAT...

10.7554/elife.96317.2 preprint EN 2024-12-06

Abstract The Roquebrune-Cap Martin basin (RCMB), developed along the eastern rim of Nice arc, represents an exclusive sedimentary marker constraining timing deformation in arc (southern Subalpine chain) during Miocene times. Structural and sedimentological analyses as well 3D geometrical modeling RCMB revealed morphological, structural features characterizing active tectonic control infills development. microstructural boundary evidenced a N-S left-lateral strike-slip ‘en echelon’ faults...

10.2113/gssgfbull.182.6.493 article EN BSGF – Earth Sciences Bulletin 2011-11-01

Abstract Tgt is the enzyme modifying guanine (G) in tRNAs with GUN anticodon to queuosine (Q). tgt required for optimal growth of Vibrio cholerae presence sub-lethal aminoglycoside concentrations. We further explored here role Q34 efficiency codon decoding upon tobramycin exposure. characterized its impact on overall bacterial proteome, and elucidated molecular mechanisms underlying effects modification antibiotic translational stress response. Using reporters, we showed that impacts at...

10.1101/2022.09.26.509455 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-09-26

The WestraliaSPAN 2D regional program extends across all basins of Australia’s North West Shelf (Carnarvon/Roebuck/Browse/Bonaparte basins) and Arafura regions. survey is designed with long offset record length (18 sec) acquisition parameters to image the important deep crustal sub architecture depositional systems this complex margin. provides unique, state-of-the-art depth imaging deep-basement rift structures Westralian Superbasin, as well lower crust Moho. has multiple transects which...

10.1071/aj13047 article EN The APPEA Journal 2014-01-01

Tgt is the enzyme modifying guanine (G) in tRNAs with GUN anticodon to queuosine (Q). tgt required for optimal growth of Vibrio cholerae presence sub-lethal aminoglycoside concentrations. We further explored here role Q efficiency codon decoding upon tobramycin exposure. characterized its impact on overall bacterial proteome, and elucidated molecular mechanisms underlying effects modification antibiotic translational stress response. Using reporters, we showed that impacts at tyrosine TAT...

10.7554/elife.96317.1 preprint EN 2024-06-05
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