A5065739906- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Opioid Use Disorder Treatment
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
- Substance Abuse Treatment and Outcomes
- LGBTQ Health, Identity, and Policy
- Sexuality, Behavior, and Technology
- Homelessness and Social Issues
- HIV Research and Treatment
- Forensic Toxicology and Drug Analysis
- Pain Management and Opioid Use
- HIV/AIDS drug development and treatment
- Cannabis and Cannabinoid Research
- Treatment of Major Depression
- HIV-related health complications and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Prenatal Substance Exposure Effects
- HIV/AIDS oral health manifestations
- Mental Health and Patient Involvement
- Mental Health Treatment and Access
- Migration, Health and Trauma
- Adolescent and Pediatric Healthcare
- Child and Adolescent Health
- Pain Management and Placebo Effect
British Columbia Centre on Substance Use
2021-2025
University of British Columbia
2014-2024
St. Paul's Hospital
2024
St. Paul's Hospital
2014-2023
Simon Fraser University
2014-2023
AIDS Vancouver
2014-2022
Vancouver Coastal Health
2018
ViiV Healthcare (Spain)
2018
University of Victoria
2016
Michael Smith Health Research BC
2016
Background: We developed estimates of community viral load (VL) and risk factors for unsuppressed VL from a cross-sectional study men who have sex with (MSM) in Vancouver, Canada. Methods: MSM were recruited February 25, 2012 to 28, 2014 using respondent-driven sampling (RDS). Participants completed computer-assisted self-interview questionnaire nurse-administered point-of-care HIV test. For HIV-positive participants, we conducted CD4 cell counts. used RDS-weighted analysis obtain population...
Assessments of gay and bisexual men's substance use often obscures salient sociocultural identity-related experiences related to how they drugs. Latent class analysis was used examine patterns represent the social, economic this population. Participants were sexually active men (including other who have sex with men), aged ≥ 16 years, living in Metro Vancouver (n = 774). LCA indicators included all substances past six months self-reported by more than 30 men. Model selection made...
Technology has changed the way men who have sex with (MSM) seek and socialize, which may impact implementation of respondent-driven sampling (RDS) among this population. Initial participants (also known as seeds) are a critical consideration in RDS because they begin recruitment chains. However, little information is available on how online-recruited seeds effect implementation.The objectives study were to compare (1) versus offline-recruited (2) subsequent chains seeds.Between 2012 2014, we...
Abstract Introduction Treatment as prevention strategies have been variously applied across provinces in Canada. We estimated HIV care cascade indicators and correlates of unsuppressed viral load (VL) among gay, bisexual other men who sex with (GBM) recruited Vancouver, Toronto Montreal. Methods Sexually active GBM, aged ≥16 years, were through respondent‐driven sampling (RDS) from February 2017 to August 2019. Participants completed a Computer‐Assisted Self‐Interview tests for sexually...
Abstract Aims We measured the association between prescribed stimulant medications and overdose among individuals receiving opioid agonist therapy (OAT) for use disorder. Design Retrospective cohort study using British Columbia Provincial Overdose Cohort, a linked administrative database. Setting used data from Columbia, Canada, January 2015 through February 2020. Participants In total, 9395 contributed 18 273 person‐years of follow‐up while dispensed OAT. Measurements examined prescription...
Introduction Awareness and knowledge of treatment as prevention (TasP) was assessed among HIV‐positive HIV‐negative gay, bisexual other men who have sex with (GBMSM) in Vancouver, Canada. Methods Baseline cross‐sectional survey data were analyzed for GBMSM enrolled, via respondent‐driven sampling (RDS), the Momentum Health Study. TasP awareness defined ever versus never heard term “TasP.” Multivariable logistic regression identified covariates awareness. Among those aware TasP, men's level...
We evaluated attitudes toward treatment as prevention (TasP) among gay, bisexual, and other men who have sex with (GBM) in Vancouver, Canada.Sexually active GBM, aged ≥16 years, were recruited between 2012 2015 using respondent-driven sampling. At each 6-month follow-up, participants completed a computer-administered questionnaire nursing visit. Repeated-measures latent class analysis, grouped by self-reported serostatus, identified patterns of TasP endorsement considering TasP-related...
Youth trauma exposure is associated with syndemic HIV risk. We measured lifetime prevalence, type, and correlates of experience by gender among adolescents living in the hyper-endemic setting Soweto, South Africa. Using data from Botsha Bophelo Adolescent Health Survey (BBAHS), prevalence "ever" experiencing a traumatic event (aged 14–19) was assessed using modified Traumatic Event Screening Inventory-Child (TESI-C) scale (19 items, study alpha = 0.63). self-reported number potentially...
Background: Studies have found that gay, bisexual, and other men who sex with (GBM) higher rates of mental health conditions substance use than heterosexual men, but are limited by issues representativeness. Objectives: To determine the prevalence correlates disorders among GBM in Metro Vancouver, Canada. Methods: From 2012 to 2014, Momentum Health Study recruited (≥16 years) via respondent-driven sampling (RDS) estimate population parameters. Computer-assisted self-interviews (CASI)...
Polysubstance use (PSU) practices are increasing among people who opioids (PWUO). However, several aspects of longitudinal PSU patterns PWUO remain understudied. This study aims to identify person-centred a cohort PWUO.
Since 1986, antiretroviral therapy (ART) has been available free of charge to individuals living with HIV in British Columbia (BC), Canada, through the BC Centre Excellence HIV/AIDS (BC-CfE) Drug Treatment Program (DTP). The Highly Active Antiretroviral Therapy (HAART) Observational Medical Evaluation and Research (HOMER) cohort was established 1996 maintain a prospective record clinical measurements medication profiles subset DTP participants initiating HAART BC. This unique provides...
Youth between the ages of 15 years to 24 account for almost half new HIV infections in South Africa.To describe study details Botsha Bophelo Adolescent Health Study (BBAHS) which was an investigation risk among adolescents living Soweto, Africa.Eligibility criteria BBAHS included being 14 - 19 old and one 41 identified formal informal areas township Soweto. A cross-sectional survey developed investigators adolescent community advisory board consisting previously validated scales original...
Background The objective of this study was to explore the relationship between online sex-seeking, community/social attachment and sexual behaviour. Methods: Respondent-driven sampling used recruit 774 sexually active gay bisexual men in Vancouver, Canada, aged ≥16 years. Multivariable logistic regression compared who had sex-seeking apps/websites past 6 months (n = 586) with those did not 188). Results: results showed that sex seekers were more likely be younger [adjusted odds ratio (aOR)...
Background The overdose crisis in North America has prompted system-level efforts to restrict opioid prescribing for chronic pain. However, little is known about how discontinuing or tapering prescribed opioids pain shapes risk, including possible differential effects among people with and without concurrent use disorder (OUD). We examined associations between discontinuation of risk on long-term therapy pain, stratified by diagnosed OUD agonist (OAT) status. Methods findings For this...
Supervised consumption sites (SCS) and overdose prevention (OPS) have been increasingly implemented in response to the ongoing epidemic Canada. Although there has a dramatic increase deaths since start of SARS-CoV 2 (COVID-19) pandemic, little is known about how SCS access may affected by this pandemic. Therefore, we sought characterize potential changes during COVID-19 pandemic among people who use drugs (PWUD) Vancouver, Canada.Between June December 2020, data were collected through...
Purpose We examined adolescents' knowledge regarding the origin of HIV/AIDS and correlates beliefs surrounding conspiracy theories in Soweto, South Africa. Now, a decade post-AIDS denialism, Africa has largest antiretroviral therapy roll-out worldwide. However, stemming from past AIDS denialism may impact HIV prevention treatment efforts. Methods Study participants were recruited through Kganya Motsha Adolescent Health Centre Perinatal Research Unit's Botsha Bophelo (BBAHS). Adolescents...