A5074197511- Reproductive Biology and Fertility
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Sperm and Testicular Function
- Reproductive System and Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Endometriosis Research and Treatment
- Hormonal and reproductive studies
- Gynecological conditions and treatments
- Uterine Myomas and Treatments
- Sexual Differentiation and Disorders
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Menopause: Health Impacts and Treatments
- Reproductive Health and Contraception
- Anesthesia and Pain Management
- Maternal and Perinatal Health Interventions
- Ovarian cancer diagnosis and treatment
- Sexual function and dysfunction studies
- Neuroendocrine regulation and behavior
- Male Reproductive Health Studies
- Menstrual Health and Disorders
- Growth Hormone and Insulin-like Growth Factors
- Prenatal Screening and Diagnostics
Universitair Ziekenhuis Brussel
2016-2025
Vrije Universiteit Brussel
2016-2025
European University Cyprus
2024-2025
University of Cyprus
2025
Serum IVF
2022-2024
National and Kapodistrian University of Athens
2021-2024
Thriasio General Hospital of Elefsina
2021-2024
Mathys (Netherlands)
2024
General Hospital of Attica
2024
Alexandria University
2021-2023
STUDY QUESTIONWhat is the impact of ovarian response on cumulative live birth rates (LBR) following utilization all fresh and frozen embryos in women undergoing their first stimulation cycle, planned to undergo single embryo transfer (SET).
Abstract The prolonged lockdown of health services providing high-complexity fertility treatments –as currently recommended by many reproductive medicine entities– is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% all infants born every year are conceived using assisted technology (ART) treatments. By contrast, the total number COVID-19 deaths reported so far represents 1.0% expected to occur worldwide over first three months current...
Abstract STUDY QUESTION Do ongoing pregnancy rates (OPRs) differ in predicted hyperresponders undergoing ART after IVM of oocytes compared with conventional ovarian stimulation (OS) for IVF/ICSI? SUMMARY ANSWER One cycle is non-inferior to one OS women serum anti-Müllerian hormone (AMH) levels ≥10 ng/ml. WHAT IS KNOWN ALREADY Women high antral follicle count and elevated AMH levels, indicating an increased functional reserve, are prone hyperresponse during treatment. To avoid iatrogenic...
Is there any association between serum 25-OH vitamin D levels and ovarian reserve markers in infertile women? Vitamin is not associated with the markers, anti-mullerian hormone (AMH) antral follicle count (AFC), women. The mechanism underlying relationship deficiency reproduction still unclear; however, evidence indicates a potential direct negative impact on function. This mainly due to fact that gonadal function may be altered by deficiency, as observed expression of receptor mRNA human...
Is elevated late-follicular phase progesterone (EP) associated with a deleterious impact on embryo quality (EQ) and cumulative live birth rates (LBRs)?EP was decrease in utilization LBRs.Ovarian stimulation promotes the production of (P) which adversely affects IVF pregnancy outcomes. However, evidence regarding potential association between EP an EQ is lacking.A retrospective analysis all GnRH antagonist down-regulated ICSI cycles followed by fresh transfer (ET) 2010 2015 performed. The...
Is natural cycle frozen-thawed embryo transfer (NC-FET) associated with better clinical pregnancy rates (CPR) when compared to modified (mNC-FET)?NC-FET is a higher CPR mNC-FET.There conflicting evidence regarding the impact of hCG triggering on outcomes after (FET), and information effect luteal phase support (LPS) lacking.This retrospective study included all (n = 2353) consecutive cycles FET vitrified cleavage blastocyst stage embryos warmed between January 2010 April 2015 in tertiary...
Does thyroid autoimmunity (TAI) predict live birth rate in euthyroid women after one treatment cycle IUI patients?TAI as such does not influence pregnancy outcome treatment.The role of TAI on the case IVF/ICSI is largely debated literature. This first study to address this issue IUI.This was a retrospective cohort study. A two-armed design performed: patients anti-thyroid peroxidase (TPO)+ and anti-TPO-. All who started their our fertility center between 1 January 2010 31 December 2014 were...
What is the effect of vitamin D deficiency on pregnancy rates following frozen embryo transfer (FET)?. Vitamin does not affect in FET cycles. Although there evidence that potential impact reproductive outcome may be mediated through a detrimental oocyte or quality, rationale our design was based derived from basic science, suggesting have key role endometrial receptivity and implantation. Only few retrospective clinical studies been published to date with conflicting results. This study...
Several infertile patients, who may even represent around 40% of the cohort, respond "suboptimally" (4-9 oocytes retrieved) following IVF, despite being predicted as normal responders. The aim our longitudinal study was to evaluate ovarian response suboptimal responders in terms number retrieved, their second IVF cycle, evaluating exclusively patients had same stimulation protocol and used or higher initial dose type gonadotropin compared previous failed attempt. Overall, analysis included...
Abstract STUDY QUESTION What is the reproductive potential following combinations of ovarian stimulation, IVM and tissue cryopreservation (OTC) in female patients seeking fertility preservation (FP)? SUMMARY ANSWER In selected patients, combining different FP procedures a feasible approach outcomes after who return to attempt pregnancy are promising. WHAT IS KNOWN ALREADY increasingly performed clinics but an algorithm select most suitable procedure according patient characteristics...
Abstract STUDY QUESTION Are the LH levels at start of ovarian stimulation predictive suboptimal oocyte yield from GnRH agonist triggering in antagonist down-regulated cycles? SUMMARY ANSWER are an independent predictor following a trigger. WHAT IS KNOWN ALREADY A ovulation trigger may result inadequate small subset patients. This failure can range empty follicle syndrome to retrieval much fewer oocytes than expected. Suboptimal response has been defined as presence circulating <15 IU/l 12...
Does the freeze-all strategy in high-responders increase pregnancy rates and improve safety outcomes when compared with GnRH agonist triggering followed by low-dose hCG intensified luteal support a fresh embryo transfer?Pregnancy after either transfer phase using or did not vary significantly; however, moderate-to-severe ovarian hyperstimulation syndrome (OHSS) occurred more frequently women who attempted transfer.Two strategies following (the approach attempt of for support) are safer...
Research question: Do live birth rates (LBRs) differ in frozen cycles of women who received single versus double embryo transfer?Design: Retrospective cohort study including underwent their first transfer (FET) a tertiary referral University Hospital between 2009–2014.Results: 3601 patients were included the analysis with 1936 (53.8%) having (SET) and 1665 (46.2%) (DET). Overall, 657/3601 (18.24%) had birth. LBR similar SET DET either for cleavage [100/757 (13.1%) 153/1032 (14.8%), p = .33]...
Abstract STUDY QUESTION Does the presence of single nucleotide polymorphisms (SNPs) in FSH receptor gene (FSHR) and/or beta subunit-encoding (FSHB) influence ovarian response predicted normal responders treated with rFSH? SUMMARY ANSWER The FSHR SNPs (rs6165, rs6166, rs1394205) has a statistically significant impact response, although this effect is minimal clinical relevance fixed dose 150 IU rFSH. WHAT IS KNOWN ALREADY Ovarian reserve markers have been breakthrough prediction following...
Which reproductive treatment outcomes are observed in women who underwent elective oocyte cryopreservation (EOC) and returned to the clinic with a desire for child?