A5030814129- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Computational Drug Discovery Methods
- Cholinesterase and Neurodegenerative Diseases
- Medicinal Plants and Neuroprotection
- Drug-Induced Hepatotoxicity and Protection
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Advanced Glycation End Products research
- Essential Oils and Antimicrobial Activity
- Malaria Research and Control
- Phytochemicals and Medicinal Plants
- Electrochemical sensors and biosensors
- Alzheimer's disease research and treatments
- Diverse Scientific Research Studies
- Analytical Methods in Pharmaceuticals
- Pharmacology and Obesity Treatment
- Seed and Plant Biochemistry
- Bee Products Chemical Analysis
- Synthesis and bioactivity of alkaloids
- Saffron Plant Research Studies
- Crystallization and Solubility Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Crystallography and molecular interactions
- Phytochemistry and Bioactivity Studies
Centurion University of Technology and Management
2021-2025
Regional Plant Resource Centre
2017-2024
Indian Institute of Chemical Biology
2015
National Institute of Pharmaceutical Education and Research
2015
Homalium zeylanicum (Gardner) Benth. (Flacourtiaceae) is a medicinal plant useful in controlling rheumatism, inflammation and diabetes. The objective of this work evaluates vitro antioxidant, antidiabetic, antiinflammatory properties hydroalcohol extract bark H. (HAHZ). It also describes isolation structure determination lucidenic acid A, which the first report plant. In order to explain role antioxidant principles, DPPH, nitric oxide, hydroxyl, superoxide metal chelating assays were...
Objective is to evaluate the ameliorative effects of Homalium zeylanicum in carbon tetrachloride-induced oxidative stress and liver injury rats. To establish nature antioxidant principles bioactive ethyl acetate fractions bark (HZEB) leaf (HZEL); oxygen radical absorbance capacity (ORAC) cell-based protection erythrocytes (CAP-e) assays were performed. From acute toxicity study, HZEB HZEL at 200 300 mg/kg b.w., relatively safe their effective doses. The degree was measured by using...
Abstract The current study describes the efficacy of B. acutangula fruit extract in wound healing via incorporation within topical gels. was produced by solvent extraction method. bioactive incorporated Carbopol 940‐based gels, which were applied topically over excision and incision wounds. change process observed till 20 days. percentages closure area 92.89 % 93.43 %, when treated with herbal gels containing 5 10 respectively. tensile strengths rats methanol fruits found to be 25±5.12 g...
Dental caries is the most prevalent oral disease. It caused by infection of Streptococcus mutans and Candida albicans. associated with inflammation dental gum. Antimicrobial agents or systemic antibiotics are administered to prevent caries. However, pathogens become drug-resistant specific antibiotics, so a combinational therapy approach may lead management In current investigation, peel Citrus sinensis (L.) Osbeck was evaluated for antimicrobial anti-inflammatory activities in Different...
Objective: To evaluate the antimalarial activity of noscapine against Plasmodium falciparum 3D7 strain (Pf3D7), its clinical isolate (Pf140/SS), and berghei ANKA (PbA). Methods: Using ring-stage survival assay, phenotypic assessments, SYBR-green-based fluorescence activities were assessed compared with dihydroartemisinin (DHA) in vivo vitro studies. In addition, hemolysis cytotoxicity tests carried out to safety. RT-PCR assay was also conducted determine effect on papain-like cysteine...
Abstract Phenyl myristate was isolated from Homalium nepalense , which is known for its therapeutic virtues in traditional medicine. However, the study of radical scavenging‐capacity phenyl limited by relatively low abundance medicinal plants. We have studied isolation, structure‐elucidation, and bioactivities high‐performance thin‐layer chromatography validated hydroalcohol‐extract bark H. . The chemical structure elucidated spectroscopic methods. performed on aluminum plates coated with...
The rapid development of drug resistant micro-organisms is a challenge to the mankind. Nano formulated compounds have proved be effective strategy combat bacterial resistance. Currently nanoparticulate systems such as nanoantibiotics are getting major attention due their low inherent toxicity, biodegradability, bioincompatibility and tuneable mechanical characteristics. antibiotics generally obtained by emulsification gelification techniques. uses polymers in encapsulation show enhancement...
Abstract Malaria is a global public health menace. The quest for new antimalarials and adjuvants malaria in the backdrop of artemisinin resistance has been enormous. This study evaluates comprehensive antimalarial activity natural phytochemical compound Noscapine, against Plasmodium falciparum 3D7 strain (Pf3D7), clinical isolate (Pf140/SS) berghei ANKA (PbA), inhibiting vitro vivo parasite growth under controlled conditions as evaluated through ring-stage survival assay, phenotypic...
<p style="text-align: justify;"><strong>Objectives:</strong> The ethyl acetate fraction of bark and leaf part <em>Homalium zelanicum </em>showed potential antioxidant hepatoprotective activities. So, this study is aimed to evaluate activities hydroalcohol extract zelanicum</em> in carbon tetrachloride induced hepatotoxicity. <strong>Methods:</strong> To potential, <em>in vitro</em> assays e.g. DPPH, superoxide, hydroxyl nitric oxide ex vivo assay cell based protection erythrocytes (CAP-e)...