- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Cardiac tumors and thrombi
- Organ Transplantation Techniques and Outcomes
- Heart Failure Treatment and Management
- Mechanical Circulatory Support Devices
- Cancer Diagnosis and Treatment
- Erythropoietin and Anemia Treatment
- Liver Disease Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Cardiomyopathy and Myosin Studies
- Parathyroid Disorders and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Transplantation: Methods and Outcomes
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- Ovarian cancer diagnosis and treatment
- Vascular Procedures and Complications
- Takotsubo Cardiomyopathy and Associated Phenomena
- Heart Rate Variability and Autonomic Control
Hospital de São João
2024
Hospital Braga
2017-2022
Hôpital Louis Pradel
2020
Lille’s Cardiology Hospital
2020
Vall d'Hebron Hospital Universitari
2012-2020
Institute of Cardiology
2019
University of Minho
2017-2018
University of North Carolina Wilmington
2016
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2009
Hospital Vargas
2006
Infective endocarditis (IE) is associated with high morbidity and mortality, despite advances in diagnosis treatment. To assess changes the epidemiological profile of IE, to perform a time-trend analysis define short-term long-term prognostic predictors IE. Retrospective 173 patients admitted IE Portuguese level II Hospital between January 1998 December 2013. The were divided into two groups according period occurrence episode (1998-2007 vs. 2008-2013). clinical event studied was death or...
Thousands of people suffer from anxiety, depression, and insomnia every day, with benzodiazepines being one the strategies used to treat these conditions. Withdrawal its long-term use can lead potentially life-threatening complications, including Takotsubo syndrome. The authors highlight an atypical case syndrome secondary benzodiazepine withdrawal, a rare complication acute substance withdrawal.
O défice de ferro (DeF) é uma condição prevalente em doentes com patologia cardíaca. Naqueles insuficiência cardíaca (IC) demonstrou‐se que esse se associa a pior prognóstico. Existem poucos dados na literatura relativamente ao impacto prognóstico do DeF nas síndromes coronárias agudas (SCA), sendo este o principal objetivo deste estudo. Estudo observacional retrospetivo incluiu 817 admitidos por SCA. Definiram‐se dois grupos acordo presença (n = 298) ou ausência 519) à admissão. evento...
Abstract Hepatitis B virus (HBV) infection was studied in 100 patients with porphyria cutanea tarda (PCT). The overall prevalence of HBV serologic markers 57%: 6 had HBsAg, 9 antiHBc alone, 2 associated antiHBe and the remaining 40 antiHBs. seropositivity frequency significantly related to age previous venesection treatment but unrelated hepatitis or risk factors, amount alcohol consumption, abnormalities serum iron levels, liver function tests, hepatosiderosis. Seropositive showed more...
A 49-year-old woman, with no relevant medical history and injectable drug use, was admitted at the hospital after a sudden dyspnoea onset. Pulmonary embolism diagnosis made on CT angiography. Three months before, she suffered hand injury an iron bar smeared dog faeces. During
Iron deficiency (IDef) is a prevalent condition in patients with heart disease and those failure (HF). Evidence has shown that this deficit associated worse prognosis. Data literature are scarce on the prognostic impact of IDef acute coronary syndromes (ACS), which main objective study. Observational, retrospective study included 817 admitted for ACS. Two groups were defined according to presence (n=298) or absence (n=519) admission. The clinical event under was occurrence death severe HF...
A 46-year-old man was admitted to the emergency department with fever and pleuritic thoracic pain. Six weeks prior admission, patient had undergone cardiac surgery. The ECG showed diffuse ST segment elevation PR depression. blood tests revealed increased inflammatory markers negative myocardial necrosis markers. Pericardial left-sided pleural effusion were noted. Sterile cultures negative. Hence, hypothesis of Dressler's syndrome established. improved clinically analytically a short course...
A 78-year-old man was urgently referred to the Department of Cardiology our hospital with a ventricular septal rupture (VSR) secondary myocardial infarction (MI). Three weeks prior admission, patient reported an episode severe chest pain lasting several hours, limiting and
A 67-year-old man with a 50 pack-year smoking history was admitted to the emergency department chest pain, irradiating his left shoulder.The patient also reported of dyspnoea in last month, productive cough, haemoptysis, and weight loss.Thoracic radiography presented consolidation upper pulmonary lobe signs pneumopericardium (Figure 1).For better
Prosthetic valve thrombosis, although rare, is a life-threatening complication of replacement surgery. The authors present an atypical case modified Bentall procedure with the CarboSeal Valsalva™ conduit complicated by early mechanical prosthetic aortic thrombosis and coronary embolism. patient was successfully treated emergency percutaneous angioplasty intracoronary thrombus aspiration left anterior descending artery, followed systemic 10 mg bolus tissue plasminogen activator ultraslow (25...
Chronic Kidney Disease (CKD) is accompanied by pathologic cardiac remodeling, including hypertrophy and fibrosis. The decline in renal function results elevations of serum concentrations phosphate (hyperphosphatemia) the bone-derived hormone Fibroblast Growth Factor (FGF) 23. Clinical studies have shown that hyperphosphatemia high circulating levels FGF23 are associated with cardiovascular mortality CKD. We previously found can directly target myocytes via FGF Receptor (FGFR) 4 induce...
Cobicistat, dolutegravir and rilpivirine are all modest inhibitors of proximal tubular creatinine secretion (IPTCrS) hence a moderate early non-progressive estimated glomerular filtration rate (Cr-eGFR) reduction has been observed in clinical trials. Data regarding the impact combination those drugs on Cr-eGFR, practice, scarcely known.Changes Cr-eGFR after starting darunavir/cobicistat alone or with and/or were studied nationwide retrospective cohort study consecutive HIV-infected patients...
Abstract Background Few women have been included in darunavir/cobicistat clinical development studies, and hardly any of them were antiretroviral experienced or treated with anything other than triple-based therapies. Objectives Our aim was to increase our knowledge about living HIV undergoing darunavir/cobicistat-based regimens. Methods A multicentre (21 hospitals), retrospective study including a centrally selected random sample HIV-1 patients starting regimen from June 2014 March 2017...
Acute antibody-mediated rejection (AMR) is having been well reported in the literature however adequate treatment remains controversial and not extensively studied. Between 2015-2019, we performed 160 liver transplants (LT). Our acute cellular rate was 32% two cases (1,2%) were AMR with different response to same treatment. The first case a 46 years-old female who underwent ABO compatible LT for hepatitis C negative viral load, MELD score 16. Donor-recipient crossmatch his panel-reactive...
Abstract Funding Acknowledgements Type of funding sources: None. Introduction Aortic stenosis (AS) is prevalent in the elderly population. When severe and patient symptomatic or left ventricular dysfunction arises, prognosis deteriorates valve replacement (AVR) recommended. During asymptomatic phase regular clinical evaluation advised to detect early onset symptoms and/or signs myocardial maladaptation. Due inherent difficulties symptoms, especially elderly, as well change when appear (even...