Thibault Leclercq

ORCID: 0000-0002-9333-3896
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About
Contact & Profiles
Research Areas
  • Cardiac Imaging and Diagnostics
  • Atrial Fibrillation Management and Outcomes
  • Viral Infections and Immunology Research
  • Acute Ischemic Stroke Management
  • Cardiac Arrhythmias and Treatments
  • Cardiac tumors and thrombi
  • Peripheral Artery Disease Management
  • Cardiac electrophysiology and arrhythmias
  • Cardiovascular Disease and Adiposity
  • Advanced X-ray and CT Imaging
  • Diabetes Treatment and Management
  • Venous Thromboembolism Diagnosis and Management
  • Advanced MRI Techniques and Applications
  • Cardiovascular Effects of Exercise
  • Cardiovascular Function and Risk Factors
  • Infective Endocarditis Diagnosis and Management
  • Cytomegalovirus and herpesvirus research
  • Cerebrovascular and Carotid Artery Diseases
  • Acute Myocardial Infarction Research
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Coronary Interventions and Diagnostics
  • Cardiac Structural Anomalies and Repair
  • Inflammatory Biomarkers in Disease Prognosis
  • Parvovirus B19 Infection Studies
  • RNA regulation and disease

CHU Dijon Bourgogne
2015-2025

Centre Georges François Leclerc
2025

AstraZeneca (Brazil)
2024

Novo Nordisk (Finland)
2024

Medtronic (United States)
2024

Maison des Sciences de l’Homme de Dijon
2016-2022

Institute of Cardiology
2021

Société Française de Cardiologie
2018

We hypothesized that the reduction of intramyocardial fat content may be involved in cardioprotective effect glucagon-like peptide-1 receptor agonists (GLP1-RA) patients with type 2 diabetes (T2D). Therefore, we aimed to evaluate change triglyceride T2D treated GLP1-RA. This monocentric proof-of-concept cohort study included unbalanced prior introduction Patients underwent cardiac magnetic resonance imaging (MRI) coupled nuclear (NMR) spectroscopy at baseline and six months after (M6) a...

10.1016/j.diabres.2025.112017 article EN cc-by Diabetes Research and Clinical Practice 2025-02-01

Stroke is a serious complication after acute myocardial infarction (AMI) and associated with an increased risk of death. Though the pathophysiological mechanisms are not exactly known, inflammation platelet reactivity could play important role in occurrence stroke during AMI. We aimed to investigate relationship between both mean volume (MPV), parameter function, C-reactive protein (CRP) in-hospital ischemic (IHS) Data were obtained from French regional survey for AMI that included 5976...

10.1080/09537104.2016.1203397 article EN Platelets 2016-07-26

Detection of left atrial appendage thrombus (LAAt) in acute stroke patients can be improved by cardiac computed tomography using prospective electrocardiogram-gated volume acquisition, which was added to the protocol our institution 2018.To evaluate factors and clinical management associated with LAAt ischemic stroke.We retrospectively included 324 consecutive from November 2018 October 2019. Clinical data post-stroke were compared no-LAAt patients.Thirty-five (10.8%; 95%CI 7.4-14.2) had 289...

10.1177/1747493020967623 article EN International Journal of Stroke 2020-11-03

Significance: Late gadolinium enhanced magnetic resonance imaging (LGE-MRI) is the gold standard technique for myocardial viability assessment. Although accurately reflects damaged tissue, there no clinical quantifying infarction (MI), demanding most algorithms to be expert dependent. Objectives and Methods: In this work a new automatic method MI quantification from LGE-MRI proposed. Our novel segmentation approach devised detecting not only hyper-enhanced lesions, but also...

10.3390/a14080249 article EN cc-by Algorithms 2021-08-20

Main objective To better understand the role of myeloperoxidases (MPO) in microvascular obstruction (MO) phenomenon and infarct size (IS) using cardiac magnetic resonance (CMR) data patients with acute myocardial infarction (AMI). Method 40 consecutive classified according to median level MPO culprit artery. A CMR study was performed during week following AMI at 6 months, late gadolinium enhancement sequences. Results Persistent MO observed same proportion (50 vs. 65%, p = 0.728) between low...

10.1371/journal.pone.0179929 article EN cc-by PLoS ONE 2017-07-13

Atrial fibrillation (AF) is one of the most common causes ischemic stroke. It essential to target patients at highest risk AF detected after stroke (AFDAS), who should benefit from a prolonged rhythm screening strategy. Cardiac-CT angiography (CCTA) was added protocol used in our institution 2018. We sought assess, for AFDAS, predictive value atrial cardiopathy markers by CCTA performed on admission acute stroke.From November 2018 October 2019, consecutive with no history were included. Let...

10.1177/23969873221138197 article EN European Stroke Journal 2022-11-21

Cardiac magnetic resonance (CMR) has emerged as a reference tool for the non-invasive diagnosis of myocarditis. However, its role in follow-up (FU) after acute event is unclear. The objectives were to assess evolution CMR parameters between phase infarct-like myocarditis and 12 months thereafter identify predictive factors persistent myocardial scarring at one year.All patients with confirmed by included. was performed within 8 days following symptom onset, 3 year. One-year FU included ECG,...

10.3390/jcm10204677 article EN Journal of Clinical Medicine 2021-10-13

Background: Few data are available about brain natriuretic peptide (BNP) variation and left atrial remodeling after the appendage occlusion (LAAO) technique. Methods: Prospective study included all consecutive patients successfully implanted with an LAAO device. Contrast-enhanced cardiac computed tomography (CT) was performed before 6 weeks procedure reverse defined by increase in LA volume >10%, together blood sampling obtained before, 48 h device implantation at first visit discharge...

10.3390/jcm10153443 article EN Journal of Clinical Medicine 2021-08-03

Coronary subclavian steal syndrome (CSSS) caused by left artery (LSA) stenosis is a rare cause of myocardial infarction in patients having coronary bypass grafting (CABG), and it has also been observed after an arteriovenous fistula (AVF) was made. A 79-year-old woman who had undergone CABG years earlier AVF creation 1 month before experienced non-ST-elevation (NSTEMI). While selective catheterization the internal thoracic graft impossible, computed tomography scanner showed patency all...

10.1002/ehf2.14341 article EN cc-by-nc ESC Heart Failure 2023-03-05

<title>Abstract</title> <bold>Background</bold> The use of GLP1 receptor agonists is associated with a reduction in cardiovascular events patients type 2 diabetes (T2D). mechanisms underlying this protection are not fully understood. We hypothesized that the intramyocardial fat content may be involved cardioprotective effect agonists. Therefore, we aimed to evaluate change triglyceride T2D treated <bold>Methods</bold> This monocentric cohort study included unbalanced prior introduction...

10.21203/rs.3.rs-4706592/v1 preprint EN cc-by Research Square (Research Square) 2024-08-10

Familial hypercholesterolaemia is a well-known disorder, but clinical diagnoses tend to be delayed. Acute coronary syndrome may occur in childhood.Our patient, young boy with homozygous familial hypercholesterolaemia, complained of persistent chest pain at rest and suffered non-ST-elevation myocardial infarction (NSTEMI). The diagnosis NSTEMI was made on the basis his features, dynamic electrocardiogram changes, troponin elevation, cardiac computed tomography findings. patient managed...

10.1093/ehjcr/ytz233 article EN cc-by-nc European Heart Journal - Case Reports 2020-01-13

Background: Immunosuppressive therapy (IST) is the cornerstone of aetiologic treatment autoimmune myocarditis.Based on previous and updated evidence, dual including prednisone (PDN) azathioprine (AZA) a recognized safe effective scheme for most patients.Purpose: We present experience our center about IST in myocarditis, focusing particular possible side effects.Methods: prospectively evaluated consecutive patients undergoing myocarditis.Diagnosis virus-negative active myocarditis was...

10.1093/eurheartj/ehy563.p4522 article EN European Heart Journal 2018-08-01
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