A5101718601- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Testicular diseases and treatments
- Ferroptosis and cancer prognosis
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Radiomics and Machine Learning in Medical Imaging
- Cancer-related cognitive impairment studies
- CNS Lymphoma Diagnosis and Treatment
- Lanthanide and Transition Metal Complexes
- Lymphoma Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cancer Cells and Metastasis
- Hormonal Regulation and Hypertension
- Radiopharmaceutical Chemistry and Applications
- Meningioma and schwannoma management
- Metastasis and carcinoma case studies
- Frailty in Older Adults
- Effects of Radiation Exposure
- Colorectal Cancer Treatments and Studies
- Neuroblastoma Research and Treatments
- Immune cells in cancer
Peking University People's Hospital
2025
Peking University
2025
Xinjiang University
2025
Zhujiang Hospital
2023-2025
Southern Medical University
2023-2025
Xinjiang Institute of Materia Medica
2025
First Affiliated Hospital of Xiamen University
2024
State Key Laboratory of Oncology in South China
2023
Guangdong 999 Brain Hospital
2019-2023
Sun Yat-sen University
2023
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic worldwide. Long non-coding RNAs (lncRNAs) are subclass of endogenous, non-protein-coding RNA, which lacks an open reading frame and is more than 200 nucleotides in length. However, the functions for lncRNAs COVID-19 have not been unravelled. The present study aimed at identifying related based on RNA sequencing peripheral blood mononuclear cells from...
Liu Y-F, Wu L-A, Wang J, Wen L-Y, X-J. Micro-computerized tomography analysis of alveolar bone loss in ligature- and nicotine-induced experimental periodontitis rats. J Periodont Res 2010; 45: 714–719. © 2010 John Wiley & Sons A/S Background Objective: Nicotine reportedly is a risk factor for periodontitis, but accurate data regarding lacking. The aim this study was to quantitatively assess rats using micro-computerized (micro-CT). Material Methods: Thirty-six adult male were treated by...
Intracranial non-germinomatous germ cell tumors (NGGCTs) are rare pediatric central nervous system (CNS) tumors. Growth impairment induced by radiation treatment was rarely evaluated. We aimed to evaluate the impacts of radiotherapy on height development as well dosimetric constraints, providing potential insights for hormonal replacement treatment. A total 128 patients diagnosed with NGGCTs were retrospectively studied. Sex, age at irradiation, physical doses and biologically effective dose...
ABSTRACT The question of how the baseline Raman spectroscopy impacts data models has remained unexplored. In this research, we utilized three spectral datasets—raw, preprocessed, and data—to construct identification for breast cancer molecular subtypes using four machine learning algorithms examined analyzed influence on performance these models. cell subtypes, regardless whether they pertained to normal or cells, preprocessed consistently yielded most optimal model performance, trailed by...
The seeds of Cichorium glandulosum Boiss. et Huet. (CS) are known for various effects. However, the research on establishment quality evaluation standards CS is currently limited. Therefore, this study employed Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS) to analyze components CS. Forty-nine compounds were identified through manual analysis and database comparison. then verified using HPLC standards. Additionally, 19 batches collected establish fingerprint...
Abstract Background and purpose Leptomeningeal metastasis (LM) is a rare but detrimental complication in patients with non-small cell lung cancer (NSCLC). Although whole brain radiotherapy (WBRT) used to eliminating cells or microscopic foci, it becoming less favorable due the concerns over neurocognitive toxicity. This study aimed re-evaluate role of WBRT setting modern targeted therapy. Materials methods From December 2014 March 2019, 80 NSCLC cytologically and/or radiologically proven LM...
Metastases to the central nervous system (CNS) are devastating neurological complications. Circulating cell-free tumor DNA (ctDNA) from cerebrospinal fluid (CSF) better represents genomic alterations in CNS tumors compared plasma (PLA). However, clinical value of as a liquid biopsy medium non-small cell lung cancer patients with leptomeningeal metastases (NSCLC-LM), regardless extracranial evolution, remains unclear.14/48 NSCLC-BM and 34/48 NSCLC-LM were enrolled this study. The mutation...
Since autophagy and the immune microenvironment are deeply involved in tumor development progression of Lower-grade gliomas (LGG), our study aimed to construct an autophagy-related risk model for prognosis prediction investigate relationship between signature LGG. Therefore, we identified six genes (BAG1, PTK6, EEF2, PEA15, ITGA6, MAP1LC3C) build training cohort (n = 305 patients) verify prognostic validation 128) whole 433), based on data from The Cancer Genome Atlas (TCGA). six-gene could...
Abstract Background Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) provide a better prognosis in EGFR -mutant non-small cell lung cancer (NSCLC). Nevertheless, the outcome of leptomeningeal metastasis (LM) remains poor. In addition, due to limited access intracranial tumour tissue, gene alterations associated with from adenocarcinoma (LM-LUAD) are unclear. Methods Forty-five patients LM-LUAD May 2019 June 2021 Guangdong Sanjiu Brain Hospital were enrolled this study....
Aim: We evaluated the incidence, clinicopathological features, prognostic factors and survival of gastric cancer (GC) with bone metastasis in a single large center China. Patients & methods: GC were retrospectively analyzed. Overall was estimated using Kaplan-Meier method. Clinicopathological factors, which associated for survival, evaluated. Results: The incidence 11.3% metastatic patients. Median overall time 6.5 months. Multivariate analysis revealed two independent poor factors: Eastern...
Background Leptomeningeal metastases (LM) have become increasingly common in non-small cell lung cancer (NSCLC) patients who harbor epidermal growth factor receptor ( EGFR ) mutation treated with -TKI and are correlated inferior prognosis. Evidence prior research demonstrated that amplification was more likely presented advanced clinical stages associated worse survival. However, whether is a prognostic marker NSCLC–LM still inconclusive. Methods This study enrolled diagnosed from June 2019...
To investigate the X-ray-specific sensitive genes and potential signaling pathways involved in latent period of radiation-induced lung injury (RILI) mouse models.Mice were randomized into groups for whole thoracic irradiation with a single fraction 20 Gy X-ray or 12.5 carbon heavy ion. Lungs harvested 3 weeks after irradiation, RNA was extracted detected genome-wide transcriptional microarrays. Differentially expressed (DEGs) calculated each group determined, followed by gene enrichment...
Gliomas are the malignance of a poor prognosis. The current WHO classification remains unable to predict survival outcomes accurately. Novel surrogates highly required for improved stratification patients and hence, allowing delivery most appropriate treatment.Transcriptional profiles 301 glioma cases on platform Chinese Glioma Genome Atlas (CGGA) were retrospectively studied.Extracellular matrix (ECM) scores established by integrating panel featured gene-signatures, correlating well with...
It is well-known that genomic mutational analysis plays a significant role in patients with NSCLC for personalized treatment. Given the increasing use of stereotactic radiosurgery (SRS) brain metastases (BM), there an emerging need more precise assessment survival outcomes after SRS. Patients BM and treated by SRS were eligible this study. The primary endpoint was overall (OS). Cox regression models used to identify independent prognostic factors. A predictive nomogram developed evaluated...
Stroke is a rare but fatal complication of advanced cancer with Trousseau syndrome, especially as initial symptoms. Here, we report the clinical characteristics, treatment, and prognosis patients non-small cell lung (NSCLC) who initially presenting acute multiple cerebral infarction.The imaging, oncological outcomes 10 diagnosed syndrome NSCLC between 2015 2021 at Guangdong Sanjiu Brain Hospital were retrospectively collected analyzed. The course two typical cases presented.All...