A5086584476- Pregnancy and preeclampsia studies
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Advanced Memory and Neural Computing
- Cancer Immunotherapy and Biomarkers
- Neonatal Respiratory Health Research
- Oral microbiology and periodontitis research
- Thermochemical Biomass Conversion Processes
- Preterm Birth and Chorioamnionitis
- Glioma Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Gestational Diabetes Research and Management
- Reproductive Health and Contraception
- Phase-change materials and chalcogenides
- Pregnancy and Medication Impact
- Glycosylation and Glycoproteins Research
- Infant Nutrition and Health
- Chalcogenide Semiconductor Thin Films
- Cardiac Health and Mental Health
- Bariatric Surgery and Outcomes
- Ectopic Pregnancy Diagnosis and Management
- Anesthesia and Neurotoxicity Research
- Ferroelectric and Piezoelectric Materials
- Multiple Myeloma Research and Treatments
- Neuroblastoma Research and Treatments
Huazhong University of Science and Technology
2018-2025
Guangdong 999 Brain Hospital
2023-2025
Anhui Jianzhu University
2022-2025
Southwest University of Science and Technology
2025
Shanxi Academy of Medical Sciences
2023-2024
Shanxi Medical University
2023-2024
Zhongnan Hospital of Wuhan University
2022-2024
Wuhan University
2022-2024
The University of Texas Medical Branch at Galveston
2019-2024
Hangzhou Women’s Hospital
2024
How cancer cells evade the therapeutic effects of immune checkpoint blockade is largely unknown. Here, we report that fibrinogen-like protein 1 (FGL1), a newly identified ligand, was modified by acetylation at Lys 98 in hepatocellular carcinoma (HCC), which targeted it for proteasomal degradation. Sirtuin 2 (SIRT2) deacetylated and stabilized FGL1, thus promoting evasion. Notably, SIRT2 inhibitor 2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide (AGK2) enhanced FGL1...
Background: Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide but the incidence its risk factors in China limited. The objective this study to investigate PPH Chinese women. Methods: A multi-center retrospective pregnant women at ≥28 weeks gestation was conducted. Logistic regression used identify potential receiver operating characteristic curve evaluate predictive performance identified factors. Subgroup analysis focusing on number fetus mode...
Intracranial non-germinomatous germ cell tumors (NGGCTs) are rare pediatric central nervous system (CNS) tumors. Growth impairment induced by radiation treatment was rarely evaluated. We aimed to evaluate the impacts of radiotherapy on height development as well dosimetric constraints, providing potential insights for hormonal replacement treatment. A total 128 patients diagnosed with NGGCTs were retrospectively studied. Sex, age at irradiation, physical doses and biologically effective dose...
In Brief OBJECTIVE: To evaluate whether sustained transabdominal uterine massage can reduce blood loss after vaginal delivery. METHODS: this multicenter randomized controlled trial, eligible women who had delivered vaginally were randomly assigned to receive 10 units oxytocin intramuscularly immediately delivery of the shoulder plus 30 minutes placenta or alone. The primary outcome was 400 mL more in 2 hours neonate. Secondary outcomes included 1,000 more, delivery, use therapeutic...
Introduction: More than 42 million people are estimated to suffer from valvular heart disease (VHD) worldwide with a prevalence of 5.3% 7.7% in the Chinese adult population. The purpose this study was examine associations between symptoms, hope, self-management behaviors, and quality life (QOL) for preoperative patients symptomatic VHD rural area China. Method: This descriptive comparative that took place Nanning, China, January 2015 March 2016. sample 128 VHD. Data were collected using...
Epitaxial BaxSr1−xTiO3 (BST) films are grown on SrTiO3:Nb (NSTO) substrates by hydrothermal means. A Pt/BST/NSTO device exhibits typical rectification characteristics under relatively low voltage and forming-free bipolar resistive switching high voltage, with the resistance ratio between states exceeding four orders of magnitude. Furthermore, negative differential arises during reset process, multilevel is achieved various voltages. These behaviors in likely due to trapping/detrapping...
Phase change memory (PCM) is an important element in the development and realization of new forms brain-like computing. In this article, a three-dimensional finite method simulation carried out to study temperature profiles within PCM cells for better understanding switching operations. On basis difference method, consists phase transition kinetics, electrical, thermal, percolation effect, as well thermoelectric effects, using temperature-dependent material parameters. The Thomson effect...
The aim of this study was to compare the effectiveness and safety intramuscular phloroglucinol oral misoprostol for cervix pretreatment before diagnostic hysteroscopy. Several modalities cervical priming pain reduction have been adopted reduce complications related dilatation Among them, prostaglandin analog is most frequently used agent. Phloroglucinol, a spasmolytic, has also showed an effect in inducing but rarely One hundred twenty outpatients undergoing anesthesia-free hysteroscopy were...
Objectives. To characterize the changes in level of T helper 1 (Th1)- [interleukin (IL)-2 and tumor necrosis factor (TNF)-α] Th2-type cytokine (IL-10) ratios Th1/Th2 (IL-2/IL-10 TNF-α/IL-10) placentae from women with preeclampsia gestational hypertension. Methods. Placental levels IL-2, TNF-α, IL-10 were determined radioimmunoassay calculated 22 preeclampsia, 15 hypertension, 32 normal term pregnant women. Results. Although had trend increase placental IL-2 TNF-α decrease IL-10, there not...
With the comprehensive implementation of second child policy in China, proportion multiparous women has increased dramatically past few years. As nearly half them have a history previous cesarean delivery, there is widespread concern regarding complications their pregnancy.The aim this study was to evaluate effect delivery mode on subsequent pregnancy outcomes real world based data from Chinese birth registry. Birth registry July 1, 2016 June 30, 2017 among population were collected and...
MicroRNA (miRNA) is a kind of non-coding RNA that regulates gene expression and involved in tumor development. MiRNA-125 reportedly aberrantly expressed colorectal cancer tissue; however, its potential function underlying mechanism remain unclear. The present study aimed to investigate the level role miRNA-125 family invasion migration cancer.To further understand metastatic cancer, we overexpressed SW480 cell line by transfection with mimics or sponge. Methyl thiazolyl tetrazolium (MTT)...
The Patient-Reported Outcomes Measurement Information System 29-item Profile (PROMIS-29) has been widely used to measure health outcomes from the patient's perspective. It not validated in adults with aortic disease. aim of this study was explore reliability and validity Chinese PROMIS-29 among patients undergoing surgery for dissection (AD).A cross-sectional design applied. Eligible completed a questionnaire that contained legacy measures, including Short Form-12 Health Survey (SF-12),...
Background The current exploration of the tumor immune microenvironment is enthusiastic, but few studies explored impact angiogenesis on microenvironment. Immunotherapy combined with anti-angiogenesis therapy has become one first-line treatment for lung adenocarcinoma. Our study aimed to explore reasons resistance immunotherapy, and markers immunotherapy therapy. Methods First, by unsupervised clustering 36 angiogenesis-related genes in adenocarcinoma patients from TCGA database, AGS1 AGS2...
Women with overweight or obesity and gestational diabetes mellitus (GDM) are at a high risk of developing type 2 (T2DM) other metabolic diseases. Healthy postpartum lifestyles in women GDM important for effectively preventing early T2DM occurrence; however, few studies guidelines focus China on this issue.This qualitative study aimed to understand the puerperium experience lifestyle overweight/obesity GDM.A face-to-face, in-depth, semi-structured interview was conducted using hermeneutical...