Alexander S. Young

ORCID: 0000-0002-9367-9213
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About
Contact & Profiles
Research Areas
  • Schizophrenia research and treatment
  • Mental Health Treatment and Access
  • Primary Care and Health Outcomes
  • Mental Health and Patient Involvement
  • Homelessness and Social Issues
  • Mental Health and Psychiatry
  • Digital Mental Health Interventions
  • Health Systems, Economic Evaluations, Quality of Life
  • Rheumatoid Arthritis Research and Therapies
  • Healthcare Policy and Management
  • Mental Health Research Topics
  • Geriatric Care and Nursing Homes
  • Chronic Disease Management Strategies
  • Health disparities and outcomes
  • Healthcare Systems and Technology
  • Health Policy Implementation Science
  • Food Security and Health in Diverse Populations
  • Psychiatric care and mental health services
  • Diabetes Management and Education
  • HIV/AIDS Research and Interventions
  • Family Caregiving in Mental Illness
  • Interprofessional Education and Collaboration
  • Cardiac Health and Mental Health
  • Obesity and Health Practices
  • Mobile Health and mHealth Applications

Center for the Study of Healthcare Provider Behavior
2015-2025

VA Greater Los Angeles Healthcare System
2016-2025

University of California, Los Angeles
2016-2025

Neurobehavioral Systems
2013-2025

Mental Illness Research, Education and Clinical Centers
2010-2024

Harvard University
2007-2024

King's College London
2023-2024

Purdue University West Lafayette
2023

Texas A&M University
2023

University of Illinois Chicago
2022

Objective: The lack of an accepted standard for measuring cognitive change in schizophrenia has been a major obstacle to regulatory approval cognition-enhancing treatments. A primary mandate the National Institute Mental Health’s Measurement and Treatment Research Improve Cognition Schizophrenia (MATRICS) initiative was develop consensus battery clinical trials treatments through broadly based scientific evaluation measures. Method: MATRICS Neurocognition Committee evaluated more than 90...

10.1176/appi.ajp.2007.07010042 article EN American Journal of Psychiatry 2008-01-03

<h3>Background</h3> Depressive and anxiety disorders are prevalent cause substantial morbidity. While effective treatments exist, little is known about the quality of care for these nationally. We estimated rate appropriate treatment among US population with disorders, effect insurance, provider type, individual characteristics on receipt care. <h3>Methods</h3> Data from a cross-sectional telephone survey conducted during 1997 1998 national sample. Respondents consisted 1636 adults probable...

10.1001/archpsyc.58.1.55 article EN Archives of General Psychiatry 2001-01-01

Objective . To examine the cause of death in a large UK inception cohort rheumatoid arthritis (RA), and whether this was related to disease duration severity, treatment effects or extra-articular features complications RA. Methods Standard clinical, laboratory, radiological socio-economic measures were recorded at baseline yearly an started nine centres 1986. Date based on certificates comparisons made with age sex matched population figures. Risk factors for mortality identified from...

10.1093/rheumatology/kel253 article EN Lara D. Veeken 2006-07-28

We introduce the Yi model family, a series of language and multimodal models that demonstrate strong multi-dimensional capabilities. The family is based on 6B 34B pretrained models, then we extend them to chat 200K long context depth-upscaled vision-language models. Our base achieve performance wide range benchmarks like MMLU, our finetuned deliver human preference rate major evaluation platforms AlpacaEval Chatbot Arena. Building upon scalable super-computing infrastructure classical...

10.48550/arxiv.2403.04652 preprint EN arXiv (Cornell University) 2024-03-07

OBJECTIVE: The study examined the relationship between mental disorders and use of complementary alternative medicine. METHOD: Data from a national household telephone survey conducted in 1997–1998 (N=9,585) were used to examine relationships medicine during past 12 months several demographic variables indicators disorders. Structured diagnostic screening interviews establish diagnoses probable RESULTS: Use was reported by 16.5% respondents. Of those respondents, 21.3% met criteria for one...

10.1176/appi.ajp.157.11.1851 article EN American Journal of Psychiatry 2000-11-01

To improve insurance coverage of mental health and substance-abuse services, the Federal Employees Health Benefits (FEHB) Program offered benefits on a par with general medical beginning in January 2001. The plans were encouraged to manage care.We compared seven FEHB from 1999 through 2002 matched set that did not have (parity benefits). Using difference-in-differences analysis, we claims patterns pairs control by examining rate use, total spending, out-of-pocket spending among users...

10.1056/nejmsa053737 article EN New England Journal of Medicine 2006-03-29

Patients with psychiatric disorders, particularly those severe mental illnesses, have high rates of undetected and untreated medical problems substantially elevated mortality due to illness. The authors sought develop a better understanding the demographic, medical, characteristics this population inform efforts improve care these persons.Using Department Veterans Affairs (VA) databases, examined use services by 175,653 patients who were treated in Southern California Nevada during fiscal...

10.1176/appi.ps.53.7.874 article EN Psychiatric Services 2002-07-01

<h3>Background</h3> Consumers and policy makers are increasingly interested in measuring treatment quality. We developed a standardized approach to the quality of outpatient care for schizophrenia used it evaluate routine care. <h3>Methods</h3> randomly sampled 224 patients at 2 public mental health clinics. Appropriate medication management was defined according criteria derived from national recommendations, focused on recent symptoms side effects. Adequate psychosocial as provision case...

10.1001/archpsyc.55.7.611 article EN Archives of General Psychiatry 1998-07-01

Objective: Mobile technologies, such as smartphones, can improve health services by delivering assessments and interventions that reach people in their daily lives. There is, however, disagreement regarding whether with serious mental illness make meaningful use of mobile technology rely on should be tailored for this population. Methods: At two clinics, 249 were interviewed phone use, cognitive functioning was assessed. Results: phones used 86% participants, including 60% who a smartphone....

10.1176/appi.ps.201900203 article EN Psychiatric Services 2019-11-20

The cost per quality-adjusted life-year (QALY) of infliximab (Remicade) treatment in rheumatoid arthritis (RA) was estimated on the basis a clinical trial comparing plus methotrexate with alone 428 patients advanced disease [Anti-Tumour Necrosis Factor Trial Rheumatoid Arthritis Concomitant Therapy (ATTRACT)].The effect progression and related costs utilities using two models based epidemiological cohorts followed for up to 15 yr Sweden UK. data were used directly model extrapolated 10...

10.1093/rheumatology/keg107 article EN Lara D. Veeken 2003-02-01

10.1007/s11414-006-9009-3 article EN The Journal of Behavioral Health Services & Research 2006-04-06

Rta, mainly encoded by open reading frame 50 (ORF50), is the product of an immediate-early gene human herpesvirus-8 (HHV-8)/Kaposi’s sarcoma-associated herpesvirus. Rta a transcriptional activator that both necessary and sufficient to disrupt viral latency activate expression downstream lytic genes. We report ectopically expressed protein could also rta promoter on reporter plasmid up 144-fold, in latently infected B cells uninfected epithelial cells, this activation was dose-dependent....

10.1099/0022-1317-81-12-3043 article EN Journal of General Virology 2000-12-01

Objectives. We compared homeless patients’ experiences of care in health organizations that differed their degree primary design service tailoring. Methods. surveyed homeless-experienced patients (either recently or currently homeless) at 3 Veterans Affairs (VA) mainstream settings Pennsylvania and Alabama, a homeless-tailored VA clinic California, highly tailored non-VA Health Care for the Homeless Program Massachusetts (January 2011-March 2012). developed survey, “Primary Quality-Homeless...

10.2105/ajph.2013.301481 article EN American Journal of Public Health 2013-10-22

This study examined the reliability and convergent, discriminant, predictive validity of Mental Illness Research, Education, Clinical Center (MIRECC) version Global Assessment Functioning (GAF) scale. The MIRECC GAF measures occupational functioning, social symptom severity on three subscales.MIRECC ratings were obtained for 398 individuals with schizophrenia or schizoaffective disorder who receiving treatment at Veterans Affairs mental health clinics. Assessments completed by using Positive...

10.1176/ps.2007.58.4.529 article EN Psychiatric Services 2007-04-01

Objective-Although effective treatments exist, individuals with depressive and anxiety disorders can remain ill for years.Little is known regarding mental health status treatment use in this population.This study provided national estimates of the prevalence persistent depression anxiety, as well illness severity, use, quality care population.Methods-Data were from a prospective, community-based cohort 1,642 adults probable major depression, dysthymia, panic disorder, or generalized disorder...

10.1176/appi.ps.59.12.1391 article EN Psychiatric Services 2008-11-25

To report from the Early Rheumatoid Arthritis Network (ERAN), time symptom onset to start of therapy, treatment choices and disease outcome in early RA.Patients with newly diagnosed RA were prospectively enrolled 19 centres UK Eire. Standardized information was collected on case forms at first presentation, 3-6 months, 1 yr annually thereafter. The choice intensity drug left discretion individual centres.A total 808 patients recruited between 2002 2007, a mean follow-up 16 (0-60) months. Of...

10.1093/rheumatology/ken406 article EN Lara D. Veeken 2008-11-04

Although effective treatments exist, individuals with depressive and anxiety disorders can remain ill for years. Little is known regarding mental health status treatment use in this population. This study provided national estimates of the prevalence persistent depression anxiety, as well illness severity, use, quality care

10.1176/ps.2008.59.12.1391 article EN Psychiatric Services 2008-12-01

Article AbstractBackground: It has been difficult to improve care for severe mental illness (SMI) in usual settings because clinical information is not reliably and efficiently managed. Methods are needed collecting this evaluate health quality. Audio computer-assisted self-interviewing (ACASI) can facilitate data collection improved outcomes a number of disorders, suggesting the need test its accuracy reliability people with SMI. Method: Ninety patients DSM-IV schizophrenia or...

10.4088/jcp.v65n1008 article EN The Journal of Clinical Psychiatry 2004-10-15
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