A5028989615- Microbial Community Ecology and Physiology
- Protist diversity and phylogeny
- Environmental DNA in Biodiversity Studies
- Marine and coastal ecosystems
- Genomics and Phylogenetic Studies
- Marine Biology and Ecology Research
- Identification and Quantification in Food
- Gut microbiota and health
- Genetic diversity and population structure
- Cancer Cells and Metastasis
- Pluripotent Stem Cells Research
- bioluminescence and chemiluminescence research
- 3D Printing in Biomedical Research
- Clinical Nutrition and Gastroenterology
- Cellular Mechanics and Interactions
- Biocrusts and Microbial Ecology
- Aquatic Ecosystems and Phytoplankton Dynamics
- Microtubule and mitosis dynamics
- Isotope Analysis in Ecology
- Child Nutrition and Water Access
- Metabolomics and Mass Spectrometry Studies
Aix-Marseille Université
2018-2024
Centre d’Immunologie de Marseille-Luminy
2023
Institut de Biologie du Développement Marseille
2023
Centre National de la Recherche Scientifique
2014-2022
Université Paris-Saclay
2019-2022
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2014-2022
Université de Toulon
2018-2022
Genoscope
2014-2022
CEA Paris-Saclay
2020-2022
Institut de Recherche pour le Développement
2018-2019
Agulhas rings provide the principal route for ocean waters to circulate from Indo-Pacific Atlantic basin. Their influence on global circulation is well known, but their role in plankton transport largely unexplored. We show that, although coarse taxonomic structure of communities continuous across choke point, South diversity altered compared with Indian Ocean source populations. Modeling and situ sampling a young ring indicate that strong vertical mixing drives complex nitrogen cycling,...
The Ocean Gene Atlas is a web service to explore the biogeography of genes from marine planktonic organisms. It allows users query protein or nucleotide sequences against global ocean reference gene catalogs. With just one click, abundance and location target are visualized on world maps as well their taxonomic distribution. Interactive results panels allow for adjusting cutoffs alignment quality displaying abundances in context environmental features (temperature, nutrients, etc.) measured...
Biogeographical studies have traditionally focused on readily visible organisms, but recent technological advances are enabling analyses of the large-scale distribution microscopic whose biogeographical patterns long been debated. Here we assessed global structure plankton geography and its relation to biological, chemical, physical context ocean (the ‘seascape’) by analyzing metagenomes communities sampled across oceans during Tara Oceans expedition, in light environmental data current...
Abstract Bathycoccus is a cosmopolitan green micro-alga belonging to the Mamiellophyceae, class of picophytoplankton that contains important contributors oceanic primary production. A single species has been described while existence two ecotypes proposed based on metagenomic data. genome available for one strain corresponding phenotype. We report second assembly obtained by cell genomics approach ecotype. The genomes are divergent enough be unambiguously distinguishable in whole DNA data...
The processes of primitive streak formation and fate specification in the mammalian epiblast rely on complex interactions between morphogens tissue organization. Little is known about how these instructive cues functionally interact to regulate gastrulation. We interrogated interplay organization by using human induced pluripotent stem cells (hiPSCs) downregulated for morphogen regulator GLYPICAN-4, which defects tight junctions result areas disrupted epithelial integrity. Remarkably, this...
Abstract Biogeographical studies have traditionally focused on readily visible organisms, but recent technological advances are enabling analyses of the large-scale distribution microscopic whose biogeographical patterns long been debated. Here we assessed global structure plankton geography and its relation to biological, chemical physical context ocean (the ‘seascape’) by analyzing metagenomes communities sampled across oceans during Tara Oceans expedition, in light environmental data...
Metagenomics offers a way to analyze biotopes at the genomic level and reach functional taxonomical conclusions. The bio-analyzes of large metagenomic projects face critical limitations: complex metagenomes cannot be assembled or annotations are much smaller than real biological diversity. This motivated development de novo read comparison approaches extract information contained in datasets. However, these new do not scale up projects, generate an important number intermediate result files....
Among marine phytoplankton, Mamiellales encompass several species from the genera Micromonas, Ostreococcus and Bathycoccus, which are important contributors to primary production. Previous studies based on single gene markers described their wide geographical distribution but led discussion because of uneven taxonomic resolution method. Here, we leverage genome sequences for six species, two each genus investigate across 133 stations sampled during Tara Oceans expedition. Our study confirms...
Severe acute malnutrition (SAM) is a multifactorial disease affecting millions of children worldwide. It associated with changes in intestinal physiology, microbiota, and mucosal immunity, emphasizing the need for multidisciplinary studies to unravel its full pathogenesis. We established an experimental model which weanling mice fed high-deficiency diet mimic key anthropometric physiological features SAM children. This alters microbiota (less segmented filamentous bacteria, spatial proximity...
Abstract Diazotrophs provide a significant reactive nitrogen source in the ocean. Increased warming and stratification may decrease nutrient availability future, forcing microbial communities toward using dissolved organic matter (DOM). Not depending on availability, diazotrophs be “winners” nutrient‐depleted However, their ability to exploit DOM influence this success. We exposed cultures of widespread Crocosphaera low (26°C, pH 8.1), moderate (28°C, 8.0), extreme (30°C, 7.9) climate change...
Abstract Although bioluminescent bacteria are the most abundant and widely distributed of all light-emitting organisms, biological role evolutionary history bacterial luminescence still shrouded in mystery. Bioluminescence has so far been observed genomes three families Gammaproteobacteria form canonical lux operons that adopt CDAB(F)E(G) gene order. LuxA luxB encode two subunits luciferase responsible for light-emission. Our deep exploration public marine environmental databases...
Article18 February 2022Open Access Source DataTransparent process Specialization of actin isoforms derived from the loss key interactions with regulatory factors Micaela Boiero Sanders orcid.org/0000-0003-3513-6779 CNRS, IBDM, Turing Centre for Living Systems, Aix Marseille Univ, Marseille, France Contribution: Conceptualization (equal), Data curation Formal analysis Validation Investigation Visualization Methodology Writing - original draft review & editing (equal) Search more papers by...
ABSTRACT The Ocean Gene Atlas is a web service to explore the biogeography of genes from marine planktonic organisms. It allows users query protein or nucleotide sequences against global ocean reference gene catalogs. With just one click, abundance and location target are visualized on world maps as well their taxonomic distribution. Interactive results panels allow for adjusting cutoffs homology displaying abundances in context environmental features (temperature, nutrients, etc.) measured...
ABSTRACT The processes of primitive streak formation and fate specification in the mammalian epiblast rely on complex interactions between morphogens tissue organization. Little is known about how these instructive cues functionally interact to regulate gastrulation. We interrogated interplay organization by using human induced pluripotent stem cells (hiPSCs) down-regulated for morphogen regulator GLYPICAN-4, which defects tight junctions result areas disrupted epithelial integrity....