Visible-infrared person re-identification (VI-ReID) is an important task in night-time surveillance applications, since visible cameras are difficult to capture valid appearance information under poor illumination conditions. Compared traditional that handles only the intra-modality discrepancy, VI-ReID suffers from additional cross-modality discrepancy caused by different types of imaging systems. To reduce both intra- and discrepancies, we propose a Hierarchical Cross-Modality...

Unlike conventional inorganic materials, biological systems are exquisitely adapted to respond their surroundings. Proteins and other molecules can process a complex set of chemical binding events as informational inputs accordingly via change in structure function. We applied this principle the design synthesis materials by preparing nanoparticles with reconfigurable surface ligands, where interparticle bonding be programmed response specific cues dynamic manner. As result, nascent...

Weakly supervised object localization has recently attracted attention since it aims to identify both class labels and locations of objects by using image-level labels. Most previous methods utilize the activation map corresponding highest source. Exploiting only one probability is often biased into limited regions or sometimes even highlights background regions. To resolve these limitations, we propose use maps, named combinational maps (CCAM), which are linear combinations from lowest...

Thesedays, Convolutional Neural Networks are widely used in semantic segmentation. However, since CNN-based segmentation networks produce low-resolution outputs with rich information, it is inevitable that spatial details (e.g., small objects and fine boundary information) of results will be lost. To address this problem, motivated by a variational approach to image (i.e., level set theory), we propose novel loss function called the which designed refine results. deal multiple classes an...

Stimuli-responsive nanomaterials with reconfigurable structures and properties have garnered significant interest in the fields of optics, electronics, magnetics, therapeutics. DNA is a powerful versatile building material that provides programmable structural dynamic properties, indeed, sequence-dependent changes already been exploited creating switchable DNA-based architectures. However, rather than designing new input sequence for each intended change, it would be useful to one simple,...

Abstract The use of DNA‐based nanomaterials in biomedical applications is continuing to grow, yet more emphasis being put on the need for guaranteed structural stability DNA nanostructures physiological conditions. Various methods have been developed stabilize origami against low concentrations divalent cations and presence nucleases. However, existing strategies typically require complete encapsulation nanostructures, which makes accessing encased strands difficult, or chemical...

The ongoing pandemic and increasing frequency of infectious disease outbreaks due to climate change, urbanization, global human migration have put great focus on nucleic acid amplification‐based diagnostic technologies (NAAT). These methods can provide gold standard accuracy sensitivity, their widespread availability at the point‐of‐care is crucial for managing spread pathogens in animal populations, as well environmental surveillance. However, so far reach NAAT‐based platforms has mostly...

Abstract Mass cytometry uses metal-isotope-tagged antibodies to label targets of interest, which enables simultaneous measurements ~50 proteins or protein modifications in millions single cells, but its sensitivity is limited. Here, we present a signal amplification technology, termed Amplification by Cyclic Extension (ACE), implementing thermal-cycling-based DNA situ concatenation combination with 3-cyanovinylcarbazole phosphoramidite-based crosslinking enable simultaneously on >30...

Significance The Hippo pathway restricts cell proliferation and plays key roles in organ size control tissue homeostasis. crucial step of this is the regulation transcriptional coactivators YAP/TAZ by LATS1/2 kinases. We report present study that deubiquitinase YOD1 acts as a positive regulator controlling size. significance our discovery regulatory mechanism for pathway: high density miR-21−YOD1−ITCH−LATS signaling cascade, which parallel to previously known MST1/2−LATS cascade. Data from...

The programmability of CRISPR-derived Cas9 as a sequence-specific DNA-targeting protein has made it powerful tool for genomic manipulation in biological research and translational applications. activity can be programmably engineered to respond nucleic acids, but these efforts have focused primarily on single-input control Cas9, until recently, they were limited by sequence dependence between parts the guide RNA detected. Here, we not only design present DNA- RNA-sensing conditional (cgRNA)...

A novel method for synthesizing and photopatterning colloidal crystals via light-responsive DNA is developed. These are composed of 10-30 nm gold nanoparticles interconnected with azobenzene-modified strands. The photoisomerization the azobenzene molecules leads to reversible assembly disassembly base-centered cubic (bcc) face-centered (fcc) crystalline nanoparticle lattices. In addition, UV light used as a trigger selectively remove on centimeter-scale thin films crystals, allowing them be...

Abstract 2D transition metal dichalcogenides (TMDs) have emerged as promising materials for advanced gas sensing platforms owing to their abundant active edge sites, high surface area, and mechanical flexibility. However, TMDs encounter low selectivity issues they show responses a variety of gases, impeding practical use discrimination. Herein, it is demonstrated that in situ growth breathable zeolitic imidazolate framework‐leaf (ZIF‐L) dramatically enhances the SnS 2 ‐based sensors H S....

Large Language Models (LLMs) enhance their problem-solving capability by leveraging both parametric and external knowledge. Beyond knowledge to improve response accuracy, they require key capabilities for reliable knowledge-handling: resolving conflicts between sources, avoiding distraction from uninformative knowledge, abstaining when sufficient is unavailable. Prior studies have examined these scenarios in isolation or with limited scope. To systematically evaluate capabilities, we...

DNA is a powerful tool for programmably assembling colloidal crystals, and has been used to generate nanoparticle superlattices with synthetically adjustable lattice parameters crystal symmetries. However, the majority of these superlattice structures remain static once constructed, factors such as interparticle distance cannot be controlled in facile rapid manner. Incorporation materials into functional devices would greatly benefitted by ability change various aspects assembly after...

Herein, we report an example of entropy-driven crystallization behavior in DNA-nanoparticle superlattice assembly, marking a divergence from the well-established enthalpic driving force maximizing nearest-neighbor hybridization connections. Such is manifested observation non-close-packed, body-centered cubic (bcc) when using system with self-complementary DNA linkers that would be predicted to form close-packed, face-centered (fcc) structure based solely on considerations and previous design...

The programmability of DNA makes it an attractive structure-directing ligand for the assembly nanoparticle (NP) superlattices in a manner that mimics many aspects atomic crystallization. However, synthesis multilayer single crystals defined size remains challenge. Though previous studies considered lattice mismatch as major limiting factor assembly, thin film growth depends on interlinked variables. Here, more comprehensive approach is taken to study fundamental elements, such temperature...

DNA-functionalized nanoparticles, including plasmonic can be assembled into a wide range of crystalline arrays via synthetically programmable DNA hybridization interactions. Here we demonstrate that such assemblies grown epitaxially on lithographically patterned templates, eliminating grain boundaries and enabling fine control over orientation size up to thousands square micrometers. We also this epitaxial growth allows for orientational control, systematic introduction strain, designed...

Chronic obstructive pulmonary disease (COPD), which is characterized by airway obstruction, leads to, as the two major forms of COPD, chronic bronchitis and emphysema. This study was conducted to evaluate effects herbal formula, PM014, in a murine model COPD. Balb/c mice were treated once with each herb extract PM014 or mixture via an oral injection. Lipopolysaccharide (LPS) elastase/LPS administrated induce that resembles treatment significantly attenuated increased accumulation immune...

In this study, we explore Human Activity Recognition (HAR), a task that aims to predict individuals' daily activities utilizing time series data obtained from wearable sensors for health-related applications. Although recent research has predominantly employed end-to-end Artificial Neural Networks (ANNs) feature extraction and classification in HAR, these approaches impose substantial computational load on devices exhibit limitations temporal due their activation functions. To address...

본 연구의 목적은 대학생의 스마트폰 중독의 문제를 예방하고, 또 이를 개입하기 위한 기초자료를 제공하고자, 현상학적 연구 방법을 사용하여, 대학생들이 스마트폰을 사용하면서 겪은 다양한 경험의 "의미"와 "본질"을 파악하고자 하였다. 참여자들은 C시에 있는 대학에 재학 중인 총 9명의 대학생들이며, 심층 인터뷰 기간은 2012년 6월 초부터 7월말이었으며, 자료는 Colaizzi의 연구방법에 따라 분석되었다. 자료분석 결과, 40개의 주제, 5개의 주제군이 도출되었으며, 1. 관계와 소통을 몸부림(무방비 상태로 인터넷에 자기 개방하기, 인터넷상에서 위로받고 싶음, 마음의 상처와 불신), 2. 과다사용 및 통제력 상실(컴퓨터보다 주로 사용, 과몰입 습관화, 저하), 3. 심리적 부적응(과도한 애착과 의존, 분리불안, 집착, 인내력 4. 일상생활 위협(우선순위 변동, 독립적 일상생활기능 퇴행, 불규칙적 생활 건강문제 발생, 무료 메신저 피해, 학업에 지장 초래), 5. 회복의...