A5087234216- Uterine Myomas and Treatments
- Extracellular vesicles in disease
- Gynecological conditions and treatments
- Single-cell and spatial transcriptomics
- Pelvic floor disorders treatments
- Cancer Immunotherapy and Biomarkers
Drexel University
2023
UPMC Hillman Cancer Center
2021
Head and neck squamous cell carcinoma (HNSCC) is characterized by complex relations between stromal, epithelial, immune cells within the tumor microenvironment (TME). To enable development of more efficacious therapies, we aim to study heterogeneity, signatures unique populations, cell-cell interactions non-immune populations in 6 human papillomavirus (HPV)+ 12 HPV- HNSCC patient matched peripheral blood specimens using single-cell RNA sequencing. Using this dataset 134,606 cells, show...
Introduction: Uterine didelphys is an uncommon Mullerian anomaly that often associated with obstructive pathology. Without early intervention, obstruction can progress to potentially fatal complications including pyometra and sepsis. Due the rarity variability of this condition, treatment options have not been systematically studied. Case Description: In case report, we discuss a 16-year-old female who presented acute sepsis secondary in setting chronic dysmenorrhea purulent vaginal...