A5041372991- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Insect symbiosis and bacterial influences
- Advanced Materials and Mechanics
- Micro and Nano Robotics
Oxford Brookes University
2024
International Centre of Insect Physiology and Ecology
2019-2021
Liverpool School of Tropical Medicine
2019
Abstract Leishmania species, members of the kinetoplastid parasites, cause leishmaniasis, a neglected tropical disease, in millions people worldwide. has complex life cycle with multiple developmental forms, as it cycles between sand fly vector and mammalian host; understanding their is critical to disease spread. One key stages haptomonad form, which attaches insect tissues through its flagellum. This adhesion, conserved across implicated having an important function within hence...
Adhesion to surfaces is a common strategy employed across biology, especially by pathogens. Within their sand fly vector, Leishmania parasites undergo multiple developmental stages, including the understudied haptomonad form, which adheres stomodeal valve via highly modified flagellum. This adhesion, likely critical for efficient transmission, mediated complex adhesion plaque from filaments in flagellum extend towards cell body and connect attachment zone (FAZ), cytoskeletal structure...
Background Phlebotomus (Larroussius) guggisbergi is among the confirmed vectors for cutaneous leishmaniasis (CL) transmission in Kenya. This scarring and stigmatizing form of accounts over one million annual cases worldwide. Most recent CL epidemics Kenya have been reported Gilgil, Nakuru County, where disease has become a public health issue. However, little known about factors that drive its transmission. Here, we sought to determine occurrence, distribution host blood feeding preference...
Abstract Background Visceral leishmaniasis (VL) and zoonotic cutaneous (ZCL) are of public health concern in Merti sub-County, Kenya, but epidemiological data on transmission, vector abundance, distribution, reservoir hosts remain limited. To better understand the disease inform control measures to reduce we investigated abundance distribution sand fly species responsible for Leishmania transmission sub-County their blood-meal hosts. Methods We conducted an entomological survey five villages...
Abstract Background Visceral leishmaniasis (VL) and zoonotic cutaneous (ZCL) are of public health concern in Merti sub-County, Kenya, but epidemiological data on transmission, vector abundance, distribution, reservoir hosts remains limited. To better understand the disease inform control measures to reduce we investigated abundance distribution sandfly species responsible for Leishmania transmission their blood-meal hosts. Methods We conducted an entomological survey five villages with...