Nandula Raghuram

ORCID: 0000-0002-9486-754X
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About
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Research Areas
  • Plant nutrient uptake and metabolism
  • Rice Cultivation and Yield Improvement
  • Plant Stress Responses and Tolerance
  • Photosynthetic Processes and Mechanisms
  • Soil Carbon and Nitrogen Dynamics
  • Phosphorus and nutrient management
  • Plant Molecular Biology Research
  • Plant Micronutrient Interactions and Effects
  • Microbial Metabolic Engineering and Bioproduction
  • Bioinformatics and Genomic Networks
  • Legume Nitrogen Fixing Symbiosis
  • Plant responses to water stress
  • Hepatitis B Virus Studies
  • Vaccine Coverage and Hesitancy
  • Advanced Data Storage Technologies
  • Atmospheric chemistry and aerosols
  • Soil and Water Nutrient Dynamics
  • Wastewater Treatment and Nitrogen Removal
  • Protein Structure and Dynamics
  • Agriculture Sustainability and Environmental Impact
  • Climate Change Policy and Economics
  • Algal biology and biofuel production
  • Crop Yield and Soil Fertility
  • Gene Regulatory Network Analysis
  • Bioeconomy and Sustainability Development

Guru Gobind Singh Indraprastha University
2015-2024

International Management Institute
2022

Delhi Development Authority
2022

Indian Agricultural Research Institute
2017

National Institute of Science, Technology and Development Studies
2010

University of Mumbai
1999-2003

Jawaharlal Nehru University
1994-1999

Centre for Science and Environment
1996

Nitrogen (N) is an essential but generally limiting nutrient for biological systems. Development of the Haber-Bosch industrial process ammonia synthesis helped to relieve N limitation agricultural production, fueling Green Revolution and reducing hunger. However, massive use fertilizer has doubled moving through global cycle with dramatic environmental consequences that threaten planetary health. Thus, there urgent need reduce losses reactive from agriculture, while ensuring sufficient...

10.3389/fsufs.2021.660155 article EN cc-by Frontiers in Sustainable Food Systems 2021-05-31

The genome-wide role of heterotrimeric G-proteins in abiotic stress response rice has not been examined from a functional genomics perspective, despite the availability mutants and evidences involving individual genes/processes/stresses. Our whole transcriptome microarray analysis (GSE 20925 at NCBI GEO) using G-alpha subunit (RGA1) null mutant (Daikoku 1 or d1) its corresponding wild type (O. sativa Japonica Nipponbare) identified 2270 unique differentially expressed genes (DEGs). Out them,...

10.3389/fpls.2016.00011 article EN cc-by Frontiers in Plant Science 2016-01-28

In the last six decades, consumption of reactive nitrogen (N r ) in form fertilizer India has been growing rapidly, whilst use efficiency (NUE) cropping systems decreasing. These trends have led to increasing environmental losses N , threatening quality air, soils, and fresh waters, thereby endangering climate-stability, ecosystems, human-health. Since it suggested that may double by 2050, there is an urgent need for scientific research support better management Indian agriculture. order...

10.3389/fsufs.2021.505347 article EN cc-by Frontiers in Sustainable Food Systems 2021-02-18

Abstract Background Recently there has been a lot of interest in identifying modules at the level genetic and metabolic networks organisms, as well single genes reactions that are essential for organism. A goal computational systems biology is to go beyond identification towards an explanation specific terms structural or evolutionary constraints. Results In Escherichia coli, Saccharomyces cerevisiae Staphylococcus aureus , we identified metabolites with low degree connectivity, particularly...

10.1186/1471-2105-7-118 article EN cc-by BMC Bioinformatics 2006-03-08

G-protein signalling components have been implicated in some individual stress responses Arabidopsis, but not comprehensively evaluated at the genetic and biochemical level. Stress emerged as largest functional category our whole transcriptome analyses of knock-out mutants GCR1 and/or GPA1 Arabidopsis (Chakraborty et al., 2015a, PloS one 10, e0117819 Chakraborty 2015b, Plant Mol. Biol., doi: 10.1007/s11103-015-0374-2). This led us to ask whether offer converging points plant's response...

10.3389/fpls.2015.01000 article EN cc-by Frontiers in Plant Science 2015-11-18

The biological improvement of fertilizer nitrogen use efficiency (NUE) is hampered by the poor characterization phenotype and genotype for crop N response NUE. In an attempt to identify phenotypic traits N-response NUE in earliest stages plant growth, we analyzed N-responsive germination, respiration, urease activities, root/shoot growth 21 Indica genotypes rice (Oryza sativa var. indica). We found that delays germination from 0 12 h a genotype-dependent source-dependent manner, especially...

10.3389/fpls.2018.01452 article EN cc-by Frontiers in Plant Science 2018-10-01

Nitrogen-use efficiency (NUE) is a function of N-response and yield that controlled by many genes phenotypic parameters are poorly characterized. This study compiled all known yield-related in rice mined them from the N-responsive microarray data to find 1,064 NUE-related genes. Many novel hitherto unreported as related NUE, including 80 transporters, 235 transcription factors (TFs), 44 MicroRNAs (miRNAs), 91 kinases, 8 phosphatases. They were further shortlisted 62 NUE-candidate following...

10.3389/fpls.2021.627955 article EN cc-by Frontiers in Plant Science 2021-06-08

Crop improvement for Nitrogen Use Efficiency (NUE) requires a well-defined phenotype and genotype, especially different N-forms. As N-supply enhances growth, we comprehensively evaluated 25 commonly measured phenotypic parameters N response using 4 treatments in six indica rice genotypes. For this, 32 replicate potted plants were grown the green-house on nutrient-depleted sand. They fertilized to saturation with media containing either nitrate or urea as sole source at normal (15 mM N) low...

10.3389/fpls.2020.587464 article EN cc-by Frontiers in Plant Science 2021-01-20

The controversy over the existence or need for G-protein coupled receptors (GPCRs) in plant signalling has overshadowed a more fundamental quest role of AtGCR1, most studied and often considered best candidate GPCR plants. Our whole transcriptome microarray analysis GCR1-knock-out mutant (gcr1-5) Arabidopsis thaliana revealed 350 differentially expressed genes spanning all chromosomes. Many them were hitherto unknown context GCR1 signalling, such as phosphate starvation, storage compound...

10.1371/journal.pone.0117819 article EN cc-by PLoS ONE 2015-02-10

Abstract G-protein signaling components have been attributed many biological roles in plants, but the extent of involvement coupled receptor 1 ( GCR1 ) with Gα GPA1 remained unknown. To address this, we performed transcriptomic analyses on Arabidopsis gpa1-5gcr1-5 double mutant and identified 656 differentially expressed genes (DEGs). MapMan Gene Ontology revealed global transcriptional changes associated external stimulus, cell wall organization/biogenesis secondary metabolite process among...

10.1038/s41598-019-42084-2 article EN cc-by Scientific Reports 2019-04-09

Abstract Assessing and managing nitrogen sustainably is imperative for achieving the 17 UN Sustainable Development Goals (SDGs) targeted 2030. South Asian countries, aware of environmental health impacts pollution, regionally as well globally, piloted 2019 resolution on sustainable management, calling urgent policy action. This paper assists Asia development by providing new insights into nitrogen-related policies in region; it makes a step-change advance an existing global analysis...

10.1088/1748-9326/ac48b2 article EN cc-by Environmental Research Letters 2022-01-06

Abstract Nitrate (N) response is modulated by light, but not understood from a genome-wide perspective. Comparative transcriptomic analyses of nitrate in light-grown and etiolated rice leaves revealed 303 249 differentially expressed genes (DEGs) respectively. A majority them were exclusive to light (270) or dark (216) condition, whereas 33 DEGs common. The latter may constitute N signaling regardless light. Functional annotation pathway enrichment the showed that primarily modulates...

10.1038/s41598-020-68917-z article EN cc-by Scientific Reports 2020-07-22

Abstract G-proteins are implicated in plant productivity, but their genome-wide roles regulating agronomically important traits remain uncharacterized. Transcriptomic analyses of rice G-protein alpha subunit mutant ( rga1 ) revealed 2270 differentially expressed genes (DEGs) including those involved C/N and lipid metabolism, cell wall, hormones stress. Many DEGs were associated with root, leaf, culm, inflorescence, panicle, grain yield heading date. The performed better total weight filled...

10.1038/s41598-021-81824-1 article EN cc-by Scientific Reports 2021-01-27
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