A5079010607- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Cardiac Arrest and Resuscitation
- Hepatocellular Carcinoma Treatment and Prognosis
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
- Trauma and Emergency Care Studies
- Optimal Experimental Design Methods
- Emergency and Acute Care Studies
- Hepatitis C virus research
- Gastrointestinal motility and disorders
- Prostate Cancer Diagnosis and Treatment
- Hepatitis B Virus Studies
- Statistical Methods in Clinical Trials
- Antibiotics Pharmacokinetics and Efficacy
- Hepatitis Viruses Studies and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Glycosylation and Glycoproteins Research
- Cardiovascular Function and Risk Factors
- Healthcare Technology and Patient Monitoring
- Distributed and Parallel Computing Systems
- S100 Proteins and Annexins
- Bacterial Identification and Susceptibility Testing
- Medical Image Segmentation Techniques
Linkou Chang Gung Memorial Hospital
2015-2024
Chang Gung University
2009-2024
National Cheng Kung University
2019-2024
Chia Nan University of Pharmacy and Science
2024
Kaohsiung Veterans General Hospital
2015-2024
Kaohsiung Medical University
2024
Min-Hwei College of Health Care Management
2021-2024
Taipei City Hospital
2023
Chang Gung Memorial Hospital
2022
Pharmac
2021
The structure-activity relationship of 18-carbon fatty acids (C(18) FAs) on human neutrophil functions and their underlying mechanism were investigated. C(18) unsaturated (U)FAs potently inhibited superoxide anion production, elastase release, Ca(2+) mobilization at concentrations <10 microM in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated neutrophils. However, neither saturated FA nor esterified UFAs these functions. inhibitory potencies decreased the following order: C(18):1...
The role of antiviral prophylaxis before chemotherapy or immunosuppressive therapy to prevent hepatitis B virus (HBV) reactivation in patients with resolved HBV infection [hepatitis surface antigen (HBsAg) negative, core antibody (anti-HBc) positive] is unclear. This study aimed evaluate the efficacy prophylactic and outcomes HBsAg-negative, anti-HBc-positive who received therapy.We retrospectively evaluated medical records underwent from January 2013 through November 2016 at a single...
Objective There is lack of scientific evidence regarding the effectiveness prehospital triage systems. This study compared two-level Taiwan Prehospital Triage System (TPTS) with five-level and Acuity Scale (TTAS) at ED arrival prediction patient outcomes utilisation medical resources. Design was a retrospective cohort study. Adult patients transported via emergency service (EMS), who arrived centre in northern during period were enrolled. TTAS acuity levels 1–2 considered comparable to...
Purpose: Various factors, such as event location and response time, influence the outcomes of out-of-hospital cardiac arrest (OHCA). Very few studies have explored delivery basic life support (BLS) to patients having OHCA at health clinics or nursing homes—settings with professional BLS providers. Thus, in this study, we compared prognostic survival between clinics, homes, other public places (eg, workplaces sports facilities/recreational areas) offer insights for optimizing outcomes....
The emergence of drug-resistant strains exacerbates the global challenge tuberculosis caused by Mycobacterium (Mtb). Central to pathogenicity Mtb is its complex cell envelope, which serves as a barrier against both immune system and pharmacological attacks. Two key components this arabinogalactan (AG) lipoarabinomannan (LAM) are polysaccharides that contain integral arabinan domains important for wall structural functional integrity. arabinofuranosyltransferase AftB terminates synthesis...
Primary tumor resection may be unfeasible in metastatic colorectal cancer. We determined the effects of bevacizumab and cetuximab therapies on survival or conversion surgery patients with cancer who did not undergo primary resection. This retrospective cohort study enrolled 8466 underwent first-line bevacizumab- cetuximab-based therapy. analyzed data both Overall after targeted therapy plus chemotherapy was assessed. The groups were matched using propensity score matching weighting....
Background/Aim: The study aimed to determine the effectiveness of cetuximab and panitumumab on survival patients with metastatic colorectal cancer or those who had undergone conversion surgery identify their prognostic factors. Patients Methods: This retrospective cohort used data from received as first-line targeted agent-based therapy. Overall rates were evaluated, factors determined. Results: A total 1,749 318 chemotherapy, respectively. similar between [hazard ratio (HR)=0.96] groups...
In Taiwan, given the discrepancy between current treatment guidelines and reimbursement options, patients might require a tool to support their decision-making process when selecting regimen for metastatic colorectal cancer, especially therapeutic strategies, subsequent costs, along with efficacy safety outcomes. Therefore, we developed patient decision aid (PDA) in choosing options recommended based on evidence those reimbursed by Taiwanese National Health Insurance.By carefully reviewing...
Background/Aim: Postoperative survival outcomes are crucial in treatment decision making. This study aimed to compare the efficacy of adjuvant chemotherapy (AC)-alone with that + targeted agents (CTA) patients metastatic colorectal cancer (mCRC) and investigate association between neoadjuvant therapy survival. Patients Methods: who underwent primary tumor excision metastasectomy were identified Taiwan Cancer Registry from 2010 2019. The analysis assessed influence on examined interactions...
Primary tumor resection and metastasectomy may be beneficial for many patients with metastatic colorectal cancer (mCRC).
Because of physiologic changes in older adults, their vital signs need to be assessed differently. This study aimed determine appropriate sign cut points for triage designation patients presented the emergency department (ED).Data from 78,524 ED visits aged ≥65 years Linkou Chang Gung Memorial Hospital (LCGMH) between 2016 and 2017 were collected. New (systolic blood pressure [SBP], heart rate [HR], body temperature [BT], Glasgow Coma Scale [GCS]) determined using critical event (the...