- Antibiotic Resistance in Bacteria
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Diagnosis and treatment of tuberculosis
- Enterobacteriaceae and Cronobacter Research
- Bacterial Identification and Susceptibility Testing
- Infections and bacterial resistance
- Pharmaceutical and Antibiotic Environmental Impacts
- Urinary Tract Infections Management
- Infectious Diseases and Tuberculosis
- Infectious Diseases and Mycology
- Infectious Disease Case Reports and Treatments
- SARS-CoV-2 and COVID-19 Research
- Actinomycetales infections and treatment
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- Malaria Research and Control
- Respiratory viral infections research
- Parasite Biology and Host Interactions
- Immunodeficiency and Autoimmune Disorders
- HIV/AIDS drug development and treatment
- Cystic Fibrosis Research Advances
- Parasites and Host Interactions
- Medical and Biological Ozone Research
- Orthopedic Infections and Treatments
ESIC Hospital
2023-2025
Employees' State Insurance Model Hospital
2023-2024
All India Institute of Medical Sciences
2017-2024
Employees State Insurance Post Graduate Institute of Medical Sciences and Research
2024
Institute of Child Health
2024
Laboratoire National de Référence
2024
LRS Institute of Tuberculosis and Respiratory Diseases
2024
All India Institute of Medical Sciences Bhopal
2017-2020
All India Institute of Medical Sciences Raipur
2017-2020
Agartala Government Medical College
2016-2017
Increasing occurrence of infections caused by multidrug-resistant Gram-negative bacteria resulted in colistin being the last agent for treatment. Apart from plasmid-mediated mcr genes, mutations involving several genes like mgrB, phoP/phoQ, pmrA, pmrB, pmrC, and crrABC are leading causes resistance. Four susceptibility testing methods were compared against broth microdilution (BMD) determined presence mcr1-5 gene.A total 100 carbapenem-resistant Enterobacterales isolates tested commercial...
Nocardiosis is known as an opportunistic infection in immunocompromised hosts. We present to you a case of pleural nocardiosis 38-year-old male patient who was chronic smoker and presented with left-sided effusion. He thrombocytopenia due immune (ITP) on steroid therapy. On admission, he found be positive for HIV. Pleural fluid sent microbiology, where acid-fast staining 1% sulfuric acid (H2SO4) showed branching filamentous rods cultures grew Nocardia, which resistant ampicillin,...
Nocardia is a type of bacteria that can cause infections in both immunocompromised and immunocompetent hosts. It an obligate aerobe commonly found the environment. Pulmonary nocardiosis may present as pneumonia, endobronchial inflammatory masses, lung abscess, cavitary disease with contiguous extension, leading to effusion empyema. We case pulmonary 75-year-old male patient 2 diabetes mellitus. The presented bilateral pneumonia hypoxia oxygen saturation 85%. Sputum samples were sent...
Tuberculosis (TB) is a chronic condition that weakens the immune system, causes structural changes in lungs, and can lead to infections by other bacterial pathogens. Very few studies have been done understand magnitude of co-infection with pathogens, so this study was conducted pattern burden. A total 174 microbiologically confirmed pulmonary TB patients' samples, identified cartridge-based nucleic acid amplification test, were further tested for pathogens culture over period five months...
Context: Under morphogenesis-inducing conditions, Candida spp. begins to undergo yeast-to-hypha switch. This shift from commensal pathogenic state is dependent on several virulence factors. Aim: To find out whether the isolated were pathogens causing vulvovaginal candidiasis or mere bystanders. Settings and Design: Cross-sectional observational study conducted 275 symptomatic hospital patients in Tripura between August 2012 April 2015. Subjects Methods: Discharge was collected identified by...
Abstract Background The prevalence of carbapenem‐resistant Enterobacteriaceae ( CRE ) is alarming worldwide causing serious infections. Rapid and accurate identification crucial to reduce the mortality morbidity. In this study, we tried develop an in‐house Carba NP test for detection evaluate its performance with others. Methods A prospective study was conducted 40 nonrepeating isolates over a period 3 months. All were screened carbapenem resistance as per CLSI 2016 guidelines followed by...
Listeria monocytogenes, a gram-positive bacillus and an intracellular pathogen, is uncommon cause of illness in the general population. During pregnancy, perinatal infection can lead to serious complications such as abortion, stillbirth, neonatal sepsis, meningitis. We present two cases meningitis caused by Christie, Atkins, Munch-Peterson (CAMP)-negative monocytogenes. In first case, seven-day-old female term neonate delivered vaginally, presented with high-grade fever refusal feed. view...
Background and Objectives: Urinary tract infection is one of the most common bacterial infections causing high morbidity mortality. Thealarming rise multidrug-resistant uropathogens worldwide forced clinician to re- think old drugs like Fosfomycin for its therapeutic management. Our objective was compare agar dilution, disc diffusion E-test method antimicrobial susceptibility testing againstdifferent drug-resistant uropathogens.
 Materials Methods: Consecutive 181 were tested using...
Multidrug-resistant tuberculosis (MDR-TB) poses a global threat that is further compounded by the human immunodeficiency virus (HIV) epidemic.To detect MDR-TB among pulmonary TB (PTB) patients with or without HIV coinfection isolating and identifying Mycobacterium from clinical samples performing drug susceptibility testing (DST).Sputum was collected presumed PTB cases. Microscopic examination performed following Ziehl-Neelsen (ZN) staining cultured in Löwenstein-Jensen (LJ) medium....
B. cepacia is metabolically versatile organism which not only resistant to many antibiotics but also disinfectants. This makes their survival easy even in restricted areas like intensive care unit (ICU) and management difficult.To describe sudden emergence of Burkholderia at a tertiary centre ICU setting milieu colistin usage.Cases were patients with culture proven B.cepacia. They picked up as non-lactose fermenting, oxidase positive, motile, gram-negative bacilli was aminoglycosides...
Background India has a disproportionately lower rate of coronavirus disease 2019 (COVID-19) severe and death rates with respect to other parts the world. It been proposed that malaria-endemic countries such as are relatively protected against COVID-19 deaths. Methods This was cross-sectional, analytical, observational study conducted from August 2020 July 2021 at tertiary care COVID-19-designated center in New Delhi, India. aimed association between antimalarial antibody levels severity...
The bacteria Achromobacter are present ubiquitously in the moist environment. Infections due to have mostly been reported immunocompromised patients. microorganism has also associated with nosocomial infections even healthy subjects. We report chronic osteomyelitis caused by denitrificans a 44-year-old male history of femoral intramedullary nail situ. organism was confirmed matrix assisted laser desorption ionization-time flight mass spectrometry (MADI-TOF MS). patient managed implant...
Background: This study aims to compare the performance of line probe assay (LPA) on smear-negative samples with that smear-positive for diagnosing pulmonary tuberculosis (PTB) and first-line drug sensitivity testing (FL DST). Methods: A total 196 sputum including both (112) negative (84) patients suspected PTB were subjected LPA TB detection FL DST. culture followed by MPT 64 Ag was done conventional DST performed all culture-positive isolates. Results compared samples. Results: The...
Background Tuberculosis (TB) remains an important public health problem worldwide. Risk of acquiring TB in patients diagnosed with cancers high and can result due to reactivation or reinfection. We share the experience a large tertiary care hospital. Materials Methods Clinical samples from presumptive while on cancer therapy were tested by smear Ziehl–Neelsen (ZN) staining, GeneXpert MTB/RIF (Gx), polymerase chain reaction (PCR), liquid culture (MGIT 960) January 1, 2019, December 31, 2022....
A 47-year-old male, a known case of alcoholic chronic liver disease with portal hypertension, presented complaints abdominal distension and shortness breath. provisional diagnosis ethanol-related compensated (CLD) hypertension splenomegaly, gross ascites bilateral hepatic hydrothorax was made. The left-sided pleural effusion subsided after three taps, but the right-sided kept refilling even four to five days repeated therapeutic so pigtail catheter left in situ. fluid sent for culture which...
Strongyloides stercoralis (S. stercoralis), a unique parasite, can cause mortal disease even years after the exposure. Iatrogenic use of steroids complicate asymptomatic infections to life-threatening hyperinfection and/or disseminated infection. Data regarding seroprevalence strongyloidiasis remains scarce and this knowledge gap needs due attention in many endemic countries including India.The present study is aimed at assessing infection need for routine screening among individuals...
Introduction: Detection of carbapenem resistance in the clinical microbiology laboratory is challenging. Production carbapenemase enzymes remains most important mechanism among Carbapenem Resistant Enterobacteriaceae (CRE). Ertapenem has been found as a sensitive marker for detecting CRE, especially non-carbapenemase producing CRE. However, limited literature available discussing its specificity and sensitivity comparison to gold standard tests. Aim: To compare ability ertapenem disc...
Abstract Urinary tract infections are one of the most common bacterial causing high morbidity and mortality. Alarming rise multidrug resistant uropathogens worldwide, forced clinician to rethink about old drugs like Fosfomycin for its therapeutic management. Our objective was compare agar dilution (AD), disc diffusion (DD) E test method antimicrobial susceptibility testing (AST) against different drug uropathogens. Consecutive 181 were tested Fosphomycin AST using AD, DD test. Results...
Splenic infarction as a complication in malaria is very sparsely reported despite having millions of cases every year. It appears to be an underreported and its recognition now can attributed the availability better diagnostic imaging modalities. important look for splenic involvement patients with malaria, especially who complain left hypochondrial pain it might associated complications. Among different species like case being here, has been most commonly described vivax outcomes have...