A5102842728- Glioma Diagnosis and Treatment
- Sexual function and dysfunction studies
- Hormonal and reproductive studies
- Metamaterials and Metasurfaces Applications
- Soft tissue tumors and treatment
- Plant Toxicity and Pharmacological Properties
- HER2/EGFR in Cancer Research
- Epigenetics and DNA Methylation
- Radiopharmaceutical Chemistry and Applications
- Cancer, Stress, Anesthesia, and Immune Response
- Extracellular vesicles in disease
- Integrated Energy Systems Optimization
- Ovarian function and disorders
- Asthma and respiratory diseases
- Renal and related cancers
- Ultrasound and Hyperthermia Applications
- Nanoparticle-Based Drug Delivery
- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- Natural Compounds in Disease Treatment
- Reproductive Health and Contraception
- Brain Metastases and Treatment
- Kruppel-like factors research
- Medicinal Plant Pharmacodynamics Research
- Advanced Antenna and Metasurface Technologies
Beijing University of Chinese Medicine
2021-2022
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2021
Southeast University
2011-2017
Xuzhou Central Hospital
2007-2017
Shuozhou Central Hospital
2012
Zhujiang Hospital
2002
Mutations in the epidermal growth factor receptor (EGFR) are commonly occurring glioblastoma. Enhanced activation of EGFR can occur through a variety different mechanisms, both ligand-dependent and ligand-independent. Numerous evidence has suggested that is overexpressed most primary glioblastomas some secondary characteristic more aggressive glioblastoma phenotypes. Additionally, recent studies have revealed wild-type EGFR, to greater extent hyper-activating mutants induced substantial...
The temperature variation rule of nano-magnetic fluid in the specific magnetic field and effect on treatment malignant glioma were examined. was investigated by heating vitro, cell morphology observed through optical microscopy electron microscopy. MTT detection also used to detect Fe3O4 nanometer hyperthermia (MFH) proliferation human U251 line. nano MFH experiment inhibition rate tumor volume nude mice with tumors. results showed that ability positively correlated its concentration at same...
Abstract Senecio scandens as a commonly used traditional Chinese medicine that is alone or in combination with other herbs preparations such QianBai BiYan tablets has attracted much attention because of its hepatotoxic pyrrolizidine alkaloids. Nowadays, most studies for alkaloids are only performed on preparation, however, production dynamic process, control toxic impurities raw materials, finished products cannot monitor the process dynamically. Thus, this study, qualitative and...
Through network pharmacology research, we found that CYP19, CYP17, AR and SRD5A2 were potential targets for lycium chinense-cuscutae semen (LC-CS) treatment of oligoasthenozoospermia. Using in vitro vivo experiments, tripterygium glycosides used to induce spermatogenic dysfunction models GC-1spg cells SD male rats, respectively, LC-CS was intervene a model. In vitro, could repair the ultrastructure damaged by (TG). Compared with TG group, upregulate protein mRNA expression SRD5A2. vivo,...
Researches were reported that respiratory diseases can lead to male infertility; however, it is unclear whether there a relationship between pulmonary fibrosis (PF) and infertility. This study examined the influence of PF on sperm quality its mechanisms. The key signalling pathway infertility caused by was predicted based bioinformatics research. After modelling, we evaluated semen quality. Real-time quantitative polymerase chain reaction Western blotting used measure protein mRNA expression...
Achyranthes bidentata Blume (Amaranthaceae) (ABR) and semen vaccariae (SV) are used commonly in the clinical treatment of erectile dysfunction males with diabetes mellitus (DMED) to strengthen kidney promote blood circulation, often achieve good curative effects.Explore mechanistic details ABR + SV against DMED.Prediction key targets by network pharmacology. A rat model DM was established streptozotocin injection (55 mg/kg). Apomorphine (100 μg/kg) injected into rats screen DMED model. Group...
Aim at cost allocation problem of cogeneration plant products, the paper presents a new heat-electricity product method named equivalent method. In method, is divided into Fixed Cost and Variable Cost. They are allocated respectively based on unit type characteristic between heat electricity product. Compared with other existent methods, reflects "deciding by heat" principle market attribute more reasonably. It observed that can promote encouraging cogeneration's investment, reducing...
Background and aim: Achyranthis Bidentatae Radix plus Semen Vaccariae are traditional Chinese medicines, which have been widely applied in the treatment of migraine Erectile Dysfunction (ED) for many years. This study verified effect improving migraine-induced ED explored its potential mechanism. Methods: Key targets signaling pathways erectile dysfunction were predicted by network pharmacology. A rat model was established nitroglycerin injection. Apomorphine injected into rats to screen...
To explore the mechanism through which liver cirrhosis (LC) causes erectile dysfunction (ED). Bioinformatic analysis was used to predict potential signalling pathways in LC-induced ED, and N-nitrosodiethylamine establish a rat model of LC. H&E staining, Western blotting RT-qPCR were detect pathological tissue damage changes mRNA protein expression levels. In addition, levels sex hormones such as estradiol (E2), prolactin (PRL) testosterone (T) measured. The hypoxia-inducible factor (HIF)...
Objective To study whether exgenous interleukin ( IL)-2, interferon IFN )-γ and IL-4 monoclonal antibody (McAb) IL-10 McAb can cause the superiority of Th2-type cytokines secretion to Thl reversion inhibit growth. Methods In vitro C6 cells were cuhured in presence exogenous IL-2, IFN-γ, McAb. The cell morphology changes observed under microscopy. gene expression Th1/Th2 was detected by using reverse transcription-polymerase chain reaction RT-PCR), inhibition rate proliferation measured...