A5078430535- Food composition and properties
- Nutritional Studies and Diet
- Diet and metabolism studies
- Metabolomics and Mass Spectrometry Studies
- Nutrition and Health in Aging
- Phytoestrogen effects and research
- Nutrition, Genetics, and Disease
- Microbial Metabolites in Food Biotechnology
- Meat and Animal Product Quality
- Diet, Metabolism, and Disease
- Celiac Disease Research and Management
- Gut microbiota and health
- Muscle metabolism and nutrition
- Folate and B Vitamins Research
- Potato Plant Research
- Consumer Attitudes and Food Labeling
- Microscopic Colitis
- Advanced Chemical Sensor Technologies
- Phytase and its Applications
- Adipose Tissue and Metabolism
- Fatty Acid Research and Health
- Isotope Analysis in Ecology
- Fermentation and Sensory Analysis
- Gastrointestinal motility and disorders
- Obesity, Physical Activity, Diet
AgResearch
2019-2024
Chalmers University of Technology
2013-2022
Lincoln University
1999-2020
University of Copenhagen
2015-2019
Nestlé (Switzerland)
2009-2018
Tufts University
2015
Newcastle University
2012-2015
General Mills (United States)
2014
Pennsylvania State University
2014
Bioanalytica (Switzerland)
2005-2013
ABSTRACT The gut microbiota enhances the host’s metabolic capacity for processing nutrients and drugs modulate activities of multiple pathways in a variety organ systems. We have probed systemic adaptation to colonization 20 days following exposure axenic mice ( n = 35) typical environmental microbial background using high-resolution 1 H nuclear magnetic resonance (NMR) spectroscopy analyze urine, plasma, liver, kidney, colon (5 time points) profiles. Acquisition was associated with rapid...
Objective To investigate whether a whole grain diet alters the gut microbiome and insulin sensitivity, as well biomarkers of metabolic health functionality. Design 60 Danish adults at risk developing syndrome were included in randomised cross-over trial with two 8-week dietary intervention periods comprising refined diet, separated by washout period ≥6 weeks. The response to interventions on composition sensitivity measures glucose lipid metabolism, functionality, inflammatory markers,...
To characterize the impact of gut microbiota on host metabolism, we investigated multicompartmental metabolic profiles a conventional mouse strain (C3H/HeJ) (n=5) and its germ-free (GF) equivalent (n=5). We confirm that microbiome strongly impacts metabolism bile acids through enterohepatic cycle (higher levels phosphocholine glycine in GF liver marked higher three compartments). Furthermore demonstrate (1) well-defined differences exist all examined compartments between metabotypes mice:...
The alkylresorcinol (AR) content of 8 commonly consumed cereals, 125 Triticum cultivars, milling fractions wheat and rye, bread, other cereal products was analyzed. ARs were found in (489−1429 μg/g), rye (720−761 triticale (439−647 barley (42−51 but not rice, oats, maize, sorghum, or millet. One durum variety to have an exceptionally low level (54 μg/g) compared varieties (589−751 species AR closely followed the ash could be used as a marker presence bran flour. Using hot 1-propanol...
Epidemiological studies have repeatedly found that whole-grain (WG) cereal foods reduce the risk of several lifestyle-related diseases, though consistent clinical outcomes and mechanisms are elusive. To compare effects a WG-rich diet with matched refined-grain (RG) on plasma biomarkers bowel health parameters, seventeen healthy subjects (eleven females six males) completed an exploratory cross-over study 2-week intervention based either WG- or RG-based foods, separated by washout at least 5...
Adherence to a low-gluten diet has become increasingly common in parts of the general population. However, effects reducing gluten-rich food items including wheat, barley and rye cereals healthy adults are unclear. Here, we undertook randomised, controlled, cross-over trial involving 60 middle-aged Danish without known disorders with two 8-week interventions comparing (2 g gluten per day) high-gluten (18 day), separated by washout period at least six weeks habitual (12 day). We find that,...
Alkylresorcinols (ARs) were first proposed as potential biomarkers of wholegrain wheat and rye intake a decade ago. Since then there has been considerable body research which suggests that ARs do meet most criteria biomarker these foods. Results from human studies on plasma AR their urinary metabolites strongly indicate compounds are responsive to whole grain correlated with various measures consumption. This review briefly summarises work the bioactivities focuses aspects related use...
Proposed global definitions of whole grain as an ingredient and food are presented by the authors on behalf Whole Grain Initiative. grains important pillar healthy sustainable diets. Internationally accepted credible ingredients whole-grain foods necessary to ensure that all stakeholders have shared standards, consumers find them clear, credible, useful. Based widely accepted, existing new developments, Definitions Working Group Initiative, with experts from academia, government agencies...
OBJECTIVE To consider the effects of whole-grain processing, specifically milling, on glycemic control in free-living adults with type 2 diabetes. RESEARCH DESIGN AND METHODS Participants this crossover trial were randomized to two interventions weeks, separated by washout. They advised replace grain foods they normally consumed intervention foods. Intervention nutrient-matched products wheat, oats, and brown rice that differed their degree processing. No other lifestyle advice was given....
The alkylresorcinol (AR) content of Swedish wheat grain samples, as well cereal ingredients and foods containing rye, was determined. average total AR in 412 μg/g (ranging between 227 639 μg/g), which is lower than that rye analyzed a previous study. relative composition homologues consistent for samples differed markedly from rye. Notably, the ratio C17:0/C21:0 ∼0.1 ∼1.0 indicating it can be used to distinguish those two cereals. commonly consumed Sweden varied widely, nondetectable levels...
Abstract A method was established for fast and easy analysis of 5‐ n ‐alkylresorcinols in rye grains, considering effects milling (intact grains versus flour), extraction solvent (ethyl acetate, methanol acetone), volume per gram sample (20 40 ml) time (3, 6, 18 24 h). For intact kernels, 1 g samples with ethyl acetate (40 ml, h) is recommended. The ease consistent the presence alkylresorcinols outer layers kernel their absence endosperm. extracts were analysed (without further purification...