Nequesha S. Mohamed

ORCID: 0000-0002-9597-0370
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About
Contact & Profiles
Research Areas
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Anesthesia and Pain Management
  • Hip and Femur Fractures
  • Healthcare Policy and Management
  • Knee injuries and reconstruction techniques
  • Glioma Diagnosis and Treatment
  • Bone and Joint Diseases
  • Health Systems, Economic Evaluations, Quality of Life
  • Cardiac, Anesthesia and Surgical Outcomes
  • Ubiquitin and proteasome pathways
  • Retinopathy of Prematurity Studies
  • Shoulder Injury and Treatment
  • Neurofibromatosis and Schwannoma Cases
  • Lower Extremity Biomechanics and Pathologies
  • Ocular Oncology and Treatments
  • Healthcare cost, quality, practices
  • Hip disorders and treatments
  • Patient Satisfaction in Healthcare
  • Opioid Use Disorder Treatment
  • Osteoarthritis Treatment and Mechanisms
  • Vitamin C and Antioxidants Research
  • Inflammatory mediators and NSAID effects
  • Venous Thromboembolism Diagnosis and Management

Atrium Health Wake Forest Baptist
2021-2025

Wake Forest University
2021-2023

Sinai Hospital
2017-2021

Aultman Hospital
2020

LifeBridge Health
2020

Seton Hall University
2019-2020

Joint Replacement Institute
2018

Cleveland Clinic
2017-2018

McGill University Health Centre
2011

McMaster Children's Hospital
2011

Recent studies have revealed that the majority of pediatric low-grade astrocytomas (PLGA) harbor BRAF-KIAA1549 (B-K) fusion gene resulting in constitutive activation RAS/MAPK pathway. However, clinical significance this genetic alteration is yet to be determined. We aimed test prognostic role B-K progression incompletely resected PLGA.We retrospectively identified 70 consecutive patients with "clinically relevant" PLGA. added 76 tumors diagnosed at our institution between 1985 and 2010 as...

10.1158/1078-0432.ccr-11-0034 article EN Clinical Cancer Research 2011-05-25

Aims Earlier studies dealing with trends in the management of osteonecrosis femoral head (ONFH) identified an increasing rate total hip arthroplasties (THAs) and a decreasing joint-preserving procedures between 1992 2008. In effort to assess new this condition, study evaluated annual versus for patients aged < or > 50 years old, incidence specific operative techniques. Methods A 219,371 ONFH were from nationwide database 1 January 2009 31 December 2015. The mean age was 54 (18 90)...

10.1302/0301-620x.102b7.bjj-2019-1611.r1 article EN The Bone & Joint Journal 2020-06-30

Aims Social determinants of health (SDOHs) may contribute to the total cost care (TCOC) for patients undergoing knee arthroplasty (TKA). The aim this study was investigate association between demographic data, status, and SDOHs on 30-day length stay (LOS) TCOC after procedure. Methods Patients who underwent TKA 1 January 2018 31 December 2019 were identified. A 234 with complete SDOH data included. Data drawn from Chesapeake Regional Information System, Centers Disease Control social...

10.1302/0301-620x.103b6.bjj-2020-2430.r1 article EN The Bone & Joint Journal 2021-05-31

Peripheral nerve injuries present a major clinical challenge due to their high morbidity and often incomplete recovery of function. While autografts remain the gold standard for repair, use is constrained by limited donor availability site complications. Alternative strategies, such as allografts tissue-engineered grafts, have been developed but are still associated with suboptimal outcomes, including chronic pain sensory disturbances. Thus, there need novel therapies that can enhance...

10.21037/atm-24-107 article EN Annals of Translational Medicine 2025-02-01

Abstract Reduced knee weight-bearing from prescription or sedentary lifestyles are associated with cartilage degradation; effects on the meniscus unclear. Rodents exposed to spaceflight hind limb unloading (HLU) represent unique opportunities evaluate this question. This study evaluated arthritic changes in medial compartment that bears highest loads across after actual and simulated spaceflight, recovery subsequent full weight-bearing. Cartilage meniscal degradation mice were measured via...

10.1038/s41598-021-90010-2 article EN cc-by Scientific Reports 2021-05-18

Background: With increased legislative efforts to utilize evidence-based medicine as a guide for clinical practice, orthopaedists feel increasing pressure publish research in higher-quality journals that reach larger audience. Impact factor (IF) is used quantify and rank journal apparent quality, the most standardized method appraisal. In this study, we assessed trends IF among orthopaedic compared these those of general surgery journals. Methods: Journal IFs from Citation Reports (JCR)...

10.21037/atm.2018.03.02 article EN Annals of Translational Medicine 2018-04-01

Hip fractures are a common condition associated with high morbidity and mortality. In this study, we assess (1) yearly incidences, (2) demographic factors, (3) postoperative outcomes, (4) primary diagnoses, (5) procedures.The National Inpatient Sample was queried for patients admitted hip from 2009 to 2016 (n = 2 761 850). Variables analyzed were age, sex, race, obesity status, Charlson Comorbidity Index, smoking osteoporosis lengths of stay (LOS), discharge dispositions, charges, costs,...

10.1177/2151459320929581 article EN cc-by-nc Geriatric Orthopaedic Surgery & Rehabilitation 2020-01-01

A new regional anaesthetic technique, coined the pericapsular nerve group (PENG) block, targets anterior hip capsule by blocking articular branches of femoral and accessory obturator nerve. In this study, we evaluated: (1) patient outcomes; (2) postoperative pain scores; (3) opioid consumption in total arthroplasty (THA) patients who received a PENG block comparison to control group.A retrospective chart review was performed for underwent primary THA met criteria at single institution (n =...

10.1177/1120700020978211 article EN Hip International 2020-12-03

Recently, 3-dimensional (3D) printing technology has been used in the development of titanium metaphyseal cones to manage severe bone loss revision total knee arthroplasty (rTKA). This study assessed (1) radiographs; (2) functional outcomes; (3) complications; and (4) 2-year implant survivorship patients receiving 3D-printed for moderate-to-severe tibial femoral rTKA. A single institution, retrospective chart review was performed with large defects treated a or cone between 2015 2017 during...

10.3928/01477447-20201202-04 article EN Orthopedics 2020-12-07

Antiretroviral therapy (ART) remains the cornerstone of decreasing morbidity and mortality in patients with human immunodeficiency virus (HIV), but additional information on its impact total hip arthroplasty (THA) complication rates is needed to mitigate risks postoperatively. Therefore, we sought examine HIV who were not taking ART compared a cohort without setting primary THA respect following outcomes: length stay, readmissions, postoperative infection.A retrospective database review was...

10.2106/jbjs.oa.20.00175 article EN cc-by-nc-nd JBJS Open Access 2021-04-01

Abstract The Centers for Medicare and Medicaid Services (CMS) have recently modified models physician compensation with the use of patient administered surveys, such as Press Ganey (PG). Currently, it is not well understood how age total knee arthroplasty (TKA) patients influences PG scores hospital ratings. Therefore, we asked: (1) there a difference in rate survey elements between < 50 years age, to 80 > (2) what factors influence overall rating various groups? database from our...

10.1055/s-0037-1603339 article EN The Journal of Knee Surgery 2017-05-23

In the United States, one-third of adults are considered obese, and demand for total knee arthroplasty (TKA) is expected to rise in these patients. Surgeons reluctant operate on obese patients, but it important understand how obesity has affected TKA utilization. This study utilizes a national database evaluate incidence, demographics, outcomes, charges, cost nonobese, overweight, nonmorbidly morbidly We queried National Inpatient Sample from 2009 2016 primary patients identifying 4,053,037...

10.1055/s-0040-1710566 article EN The Journal of Knee Surgery 2020-05-22

Inpatient dislocation following total hip arthroplasty (THA) may incur substantial financial penalties for hospitals in the United States. However, limited studies report on current incidence and variability of dislocations. We utilised a large national database to evaluate inpatient trends regarding: (1) yearly incidences; (2) lengths stay (LOS); (3) demographic factors; (4) hospital metrics.The National Sample was queried from 2012 to2016 primary THA patients (n = 1,610,155), identifying...

10.1177/1120700020940968 article EN Hip International 2020-07-27
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