A5031671670- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Elasticity and Material Modeling
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Peripheral Artery Disease Management
- Vascular Procedures and Complications
- Angiogenesis and VEGF in Cancer
- High-Temperature Coating Behaviors
- Ultrasound Imaging and Elastography
- Acute Myocardial Infarction Research
- Congenital Heart Disease Studies
- Advanced materials and composites
- Photoacoustic and Ultrasonic Imaging
- Advanced MRI Techniques and Applications
- Surgical Simulation and Training
- Cardiac Structural Anomalies and Repair
- Rheology and Fluid Dynamics Studies
- Cell Adhesion Molecules Research
- Magnesium Alloys: Properties and Applications
McGill University
2016-2025
Montreal Heart Institute
2010-2020
RELX Group (United States)
2020
London Borough of Camden
2020
Université de Montréal
1997-2015
Institut Bouisson Bertrand
2003
Limagrain (France)
2003
Polytechnique Montréal
1992-2002
Brigham and Women's Hospital
1999
Tissue-mimicking phantoms are very useful in the field of tissue characterization and essential elastography for purpose validating motion estimators. This study is dedicated to polyvinyl alcohol cryogel (PVA-C) these types applications. A strict fabrication procedure was defined optimize reproducibility having a similar elasticity. Following mechanical stretching tests, were used compare accuracy four different methods. The methods based on one-dimensional (1-D) scaling factor estimation,...
Abstract In this study, the effects of heat treatment on microstructure and mechanical properties cold sprayed stainless steel 316L coatings using N 2 He as propellant gases were investigated. Powder coating characterizations, including microhardness, porosity, XRD phase analysis performed. It was found that reduced improved inter-particle bonding, increased ductility. results confirmed no transformation occurred during deposition. Significant increase in UTS ductility observed for annealed...
The goal of this study has been to develop a numerical model the aortic valve, validate it with in-vivo data and computationally evaluate effect two types valve-sparing reconstructions on valve dynamics hemodynamics. A native models after surgical reconstruction (reimplantation straight conduit remodeling shaped conduit) were created. These transferred finite element analysis software where interaction between structures blood was taken into account in dynamic manner. Leaflet dynamics, as...
In the context of drug eluting stent, we present two-dimensional numerical models mass transport in wall and lumen to study effect diffusion coefficients three principal media (blood, vascular wall, polymer coating treated as a three-compartment problem) impact different strut apposition configurations (fully embedded, half not embedded). The conditions were analyzed terms their consequence on concentration distribution arterial wall. We apply concept therapeutic window targeted region...
Abstract Background In-stent restenosis rates have been closely linked to the wall shear stress distribution within a stented arterial segment, which in turn is function of stent design. Unfortunately, evaluation hemodynamic performance can only be evaluated with long term clinical trials. In this work we introduce set metrics, based on statistical moments, that used evaluate standardized way. They are presented context 2D flow study, analyzes impact different strut profiles for coronary...
In this work, we propose a simple method to simultaneously match the refractive index and kinematic viscosity of circulating blood analog in hydraulic models for optical flow measurement techniques (PIV, PMFV, LDA, LIF). The is based on determination volumetric proportions temperature at which two transparent miscible liquids should be mixed reproduce targeted fluid characteristics. dependence are linear relation an Arrhenius dynamic each liquid. Then mixture represented with Grunberg-Nissan...
Endothelial cells are known to respond hemodynamic forces. Their phenotype has been suggested differ between atheroprone and atheroprotective regions of the vasculature, which characterized by local environment. Once an atherosclerotic plaque formed in a vessel, obstruction creates complex spatial gradients wall shear stress. cell response stress may be linked stability coronary plaques. Unfortunately, vitro studies endothelial involvement have limited unrealistic simplified geometries,...
With the invention of coronary stent, promising clinical outcomes appeared. However, long-term success stent has been beaten by significant in-stent restenosis and consequently stents fractures (SF). Cardiologists have looking on SF as a threat to patients' life because it is associated with short- possibly morbidity rate. In this review, materials properties from perspective engineering drivers are discussed. The review also outlines how design evolved time. Opinions given merit direction...
A significant amount of evidence linking wall shear stress to neointimal hyperplasia has been reported in the literature. As a result, numerical and experimental models have created study influence stent design on stress. Traditionally, blood assumed behave as Newtonian fluid, but recently that assumption challenged. The use linear model; however, can reduce computational cost, allow fluids (e.g., glycerine water) instead analog fluid an setup. Therefore, it is interest whether model be used...