Xiao Jia

ORCID: 0000-0002-9653-9363
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Photodynamic Therapy Research Studies
  • Advanced Photocatalysis Techniques
  • GaN-based semiconductor devices and materials
  • Gas Sensing Nanomaterials and Sensors
  • Advanced Nanomaterials in Catalysis
  • Luminescence Properties of Advanced Materials
  • Porphyrin and Phthalocyanine Chemistry
  • Copper-based nanomaterials and applications
  • Iron oxide chemistry and applications
  • Nanoparticle-Based Drug Delivery
  • Luminescence and Fluorescent Materials
  • Ga2O3 and related materials
  • Ion-surface interactions and analysis
  • ZnO doping and properties
  • Hybrid Renewable Energy Systems
  • Graphene and Nanomaterials Applications
  • Graphene research and applications
  • Integrated Circuits and Semiconductor Failure Analysis
  • Semiconductor materials and devices
  • Silicon Carbide Semiconductor Technologies
  • Chemical Synthesis and Characterization
  • Fuel Cells and Related Materials
  • Metal-Organic Frameworks: Synthesis and Applications
  • Nanomaterials for catalytic reactions

Fuzhou University
2010-2025

Hainan University
2025

Jiangxi Science and Technology Normal University
2023

Shandong University
2020-2022

State Key Laboratory of Crystal Materials
2020

Luoyang Normal University
2019

Chinese Academy of Sciences
2011-2013

Institute of Modern Physics
2011

University of Chinese Academy of Sciences
2011

A new series of zinc(II) phthalocyanine derivatives have been synthesized and characterized. These macrocycles exhibited a sharp absorption band in the red visible region DMF, which indicated that they were dissolved well almost did not aggregate this solvent. Compared with unsubstituted phthalocyanine, all these phthalocyanines red-shifted Q-band (at 678-699 vs 670 nm) exhibit relatively weaker fluorescence emission higher efficiency at generating singlet oxygen. The monosubstituted...

10.1021/jm400722d article EN Journal of Medicinal Chemistry 2013-06-20

Harmful bacteria have seriously threatened human health and wealth for a long time. Herein, multifunctional drug delivery system based on UiO-66 was fabricated, it showed potent synergistic antibacterial effects when used in conjunction with photodynamic therapy chemotherapy. First, UiO-66-NH2 prepared via facile solvothermal method. Then, carboxylic zinc phthalocyanine, broad-spectrum photosensitizer, connected to by amidation. Next, chemical antibiotic linezolid loaded the pores, lysozyme...

10.1021/acs.langmuir.0c00292 article EN Langmuir 2020-03-27

α-Fe<sub>2</sub>O<sub>3</sub> porous nanorods (PNRs) with controlled morphologies were simply synthesized by thermolysis of Fe-based metal–organic framework (MIL-88A) at 500 °C.

10.1039/c6ra21567j article EN RSC Advances 2016-01-01

Hypoxia and high glutathione (GSH) contents in the tumor microenvironment (TME) diminish efficacy of single-modality photodynamic therapy (PDT) chemodynamic (CDT). Cu2O can effectively release Cu+ within TME, facilitating CDT, concurrently generate O2 to mitigate hypoxia. Co-delivery with photosensitizers (PSs) tumors could potentially enhance PDT/CDT combination therapy. However, challenges such as instability, susceptibility vivo substances affecting catalytic activity, toxicity normal...

10.1021/acsanm.4c06903 article EN ACS Applied Nano Materials 2025-01-08

Both excitation and single emission of Bi24Al2O39:Mn5+ phosphors are possible in the near-infrared (NIR) region, which can be simultaneously detected. Monitoring radiation allows us to prevent its fluctuations from affecting luminescence. Single is a technique that involves luminescence intensity ratio, so do not affect result. This has advantage involving conventional methods affected by optical dispersion, it provides reliable results suitable for practical applications. Using this method,...

10.1063/5.0243405 article EN Applied Physics Letters 2025-01-13

<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mtext>Fe</mml:mtext><mml:mn>3</mml:mn></mml:msub><mml:msub><mml:mtext>O</mml:mtext><mml:mn>4</mml:mn></mml:msub></mml:math>nanoparticle was synthesized in the solution involving water and ethanol. Then,<mml:math...

10.1155/2011/837123 article SV Journal of Nanomaterials 2010-08-11

Multi-modal synergistic therapy, especially the integration of near-infrared laser phototherapies and chemotherapy, is often sought after owing to its minimal invasiveness, low side effects, improved anticancer therapeutic efficacy. Herein, CuS nanoparticles were first coated with zinc phthalocyanine derivant (Pc)-functionalized mesoporous silica (mSiO2-Pc) achieve a drug delivery system (CuS@mSiO2-Pc) photothermal/photodynamic therapy. Chemical DOX was subsequently loaded for hyaluronic...

10.1021/acs.langmuir.2c02667 article EN Langmuir 2022-12-12

Abstract Pure and rare earth ion (Ce 3+ , Nd Pr or Sm ) doped Bi 2 WO 6 microspheres were synthesized via a facile hydrothermal process. Their physical chemical properties characterized by using X‐ray diffraction, UV‐vis diffuse reflectance spectroscopy, scanning electron microscopy, photoluminescence photoelectron spectroscopy N adsorption‐desorption isotherm analysis. Results showed that doping into leaded to decreased crystallite size, narrowed band gap increased surface area. The organic...

10.1002/slct.201903621 article EN ChemistrySelect 2019-11-22

Dasatinib is a kinase-targeted drug used in the treatment of leukemia. Regrettably, it remains far from optimal medicine due to insurmountable resistance and side effects. Photodynamic therapy (PDT) has proven that can induce systemic immune responses. However, conventional photosensitizers as immunomodulators produce anticancer immunities, which are inadequate eliminate residual cancer cells. Herein, novel compound 4 was synthesized investigated, introduces dasatinib zinc(II) phthalocyanine...

10.1021/acs.jmedchem.0c01072 article EN Journal of Medicinal Chemistry 2020-12-10

The growth mechanism and corresponding phase transitions of ZIFs derived oxide with different morphologies.

10.1039/d2ce00627h article EN CrystEngComm 2022-01-01

10.1016/j.nimb.2011.11.034 article EN Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms 2011-12-03

In this study, two novel boron dipyrromethene-based photosensitizers (BDP3 and BDP6) substituted with three or six trifluoromethyl groups have been synthesized characterized various spectroscopic methods, their photo-physical, photo-chemical, photo-biological properties also explored. The are highly soluble remain nonaggregated in N,N-dimethylformamide as shown by the intense sharp Q-band absorption. Under red light irradiation (λ = 660 nm, 1.5 J/cm²), both show high comparable cytotoxicity...

10.3390/molecules23020458 article EN cc-by Molecules 2018-02-19

A series of single-crystal α-Fe2O3 nanostructures with tunable morphologies have been prepared via a simple one-pot solvothermal synthesis. The as-prepared nanoparticles were fully characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), high-resolution TEM (HR-TEM), selective area (SAED), N2 adsorption–desorption isotherms, and other techniques. the products can be easily adjusted by controlling amount NaAc added; increasing shell thickness hollow spheres...

10.1039/c4ra07275h article EN RSC Advances 2014-09-04

10.1016/j.nimb.2011.04.118 article EN Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms 2011-05-08

10.1016/j.nimb.2012.12.101 article EN Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms 2013-01-26

Molecular dynamics simulations predict that atom doping is an efficient way to regulate the binding strength and structural changes of protein with nanomaterials, which makes it a prospective solution for design fabrication advanced nanomaterials desired function.

10.1039/d0na00365d article EN cc-by Nanoscale Advances 2020-01-01
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