A5018713691- Neurobiology and Insect Physiology Research
- Cellular Mechanics and Interactions
- Developmental Biology and Gene Regulation
- Neurogenetic and Muscular Disorders Research
- Animal Genetics and Reproduction
- CRISPR and Genetic Engineering
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Pluripotent Stem Cells Research
- Neurogenesis and neuroplasticity mechanisms
University of St Andrews
2019-2020
King's College London
2013
University of Edinburgh
2013
ABSTRACT During morphogenesis, cells exhibit various behaviours, such as migration and constriction, which need to be coordinated. How this is achieved remains elusive. morphogenesis of the Drosophila adult abdominal epidermis, larval epithelial (LECs) migrate directedly before constricting apically undergoing apoptosis. Here, we study mechanisms underlying transition from constriction. We show that LECs possess a pulsatile apical actomyosin network, change in network polarity correlates...
Abstract During morphogenesis, cells undergo various behaviours, such as migration and constriction, which need to be coordinated. How this is achieved remains elusive. morphogenesis of the Drosophila adult abdominal epidermis, larval epithelial (LECs) migrate directedly before constricting apically undergoing apoptosis. Here, we study mechanisms underlying transition from constriction. We show that LECs possess a pulsatile apical actomyosin network change in polarity underlies behavioural...