A5103225203- BRCA gene mutations in cancer
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Gynecological conditions and treatments
- PARP inhibition in cancer therapy
- Species Distribution and Climate Change
- Genomic variations and chromosomal abnormalities
- Genetic factors in colorectal cancer
- Cancer Genomics and Diagnostics
- Nutrition, Genetics, and Disease
- Marine and environmental studies
- Surgical Simulation and Training
- Marine Biology and Ecology Research
- Cephalopods and Marine Biology
- Sarcoma Diagnosis and Treatment
- Coral and Marine Ecosystems Studies
- Research Data Management Practices
- Mollusks and Parasites Studies
- Prenatal Screening and Diagnostics
- Colorectal Cancer Screening and Detection
- DNA Repair Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Colorectal Cancer Treatments and Studies
- Science, Technology, and Education in Latin America
Stanford University
2023
Kaiser Permanente
2013-2022
California Academy of Sciences
2017-2020
Gynecologic Oncology Group
2013-2020
Kaiser Permanente San Francisco Medical Center
2020
University of Virginia
2016-2017
University of California, San Francisco
2014
Large-scale analysis of the fossil record requires aggregation palaeontological data from individual localities. Prior to computers, these synoptic datasets were compiled by hand, a laborious undertaking that took years effort and forced palaeontologists make difficult choices about what types tabulate. The advent desktop computers ushered in palaeontology's first digital revolution—online literature-based databases, such as Paleobiology Database (PBDB). However, published literature...
OBJECTIVE: To evaluate the trend in uptake of salpingectomy at time hysterectomy and assess physicians' attitudes toward practice. METHODS: This was a retrospective cohort study using electronic medical record to identify women 18 years age or older undergoing from June 2011 May 2014 large integrated health care delivery system. The primary outcome change rate opportunistic over after systemwide practice recommendation issued 2013. Secondary outcomes included data on blood loss, operating...
To evaluate the utilization rate of salpingectomy for cesarean deliveries and postpartum interval tubal sterilization procedures.This is a retrospective cohort study using electronic medical record to identify women older than 18 years age undergoing surgical from June 2011 May 2016 in an integrated health care system. The primary objective describe change procedures over time after systemwide practice recommendation was issued 2013. Rates occlusion were calculated each five 1-year intervals...
The aim was to identify clinical parameters and immunohistochemical markers predictive of recurrence overall survival (OS) in a community cohort patients with primary uterine leiomyosarcoma (ULMS).All new diagnosis ULMS from 1999 2007 were identified the Kaiser Permanente Northern California pathology database. A retrospective chart review performed gather demographic data. outcomes recurrence-free OS. In addition, subset tumor samples available analyze 3 using tissue microarray techniques;...
Investigate whether disparities and other factors influence referral to genetic counseling testing for hereditary breast ovarian cancer syndrome (HBOC) in a large health care system. Examination of clinical, demographic, socioeconomic from electronic records associated with within 12 months after new diagnosed between August 1, 2013 December 31, 2018. For patients meeting institutional criteria HBOC testing, 60.6% were referred counseling, 88% whom underwent germline testing; at least one...
Evaluate the incidence and characteristics of breast cancers (BC) diagnosed following an epithelial ovarian cancer (EOC) diagnosis in women with pathogenic BRCA mutations.Retrospective cohort study all integrated healthcare system mutations EOC from 1/1/1997-12/31/2018. Primary outcome was rate subsequent BC diagnosis. Secondary outcomes included risk factors associated development BC, median time to detection EOC, method detection.There were 284 BRCA-associated identified. Fifty-two had...
Women who carry BRCA germ line mutations are at high risk for breast and ovarian cancer. The National Comprehensive Cancer Network (NCCN) other national groups have established guidelines identification of women carrying these mutations, referral genetic testing, use risk-reducing strategies management those test positive. Recommended include salpingo-oophorectomy (RRSO) by age 35 to 40 years; mastectomy (RRM); surveillance defined intervals using pelvic ultrasound, CA 125, mammogram,...