A5088785798- Intensive Care Unit Cognitive Disorders
- EEG and Brain-Computer Interfaces
- Traumatic Brain Injury and Neurovascular Disturbances
- Sepsis Diagnosis and Treatment
- Intraoperative Neuromonitoring and Anesthetic Effects
- Epilepsy research and treatment
- Restless Legs Syndrome Research
- Anesthesia and Sedative Agents
- Cardiac Arrest and Resuscitation
- Spinal Fractures and Fixation Techniques
- Transcranial Magnetic Stimulation Studies
- Heart Rate Variability and Autonomic Control
- Neuroscience and Neural Engineering
- Vagus Nerve Stimulation Research
- Pharmacological Effects and Toxicity Studies
- Functional Brain Connectivity Studies
- Sleep and Wakefulness Research
- Cardiovascular Syncope and Autonomic Disorders
- Migraine and Headache Studies
- Neural dynamics and brain function
- Peripheral Neuropathies and Disorders
- Cerebrospinal fluid and hydrocephalus
- Stuttering Research and Treatment
- Neural and Behavioral Psychology Studies
- Laser Applications in Dentistry and Medicine
Assistance Publique – Hôpitaux de Paris
2015-2025
Inserm
2013-2025
Université de Versailles Saint-Quentin-en-Yvelines
2013-2025
Université Paris-Saclay
2020-2025
Hôpital Raymond-Poincaré
2015-2024
Hôpital Saint-Antoine
2023
Sorbonne Université
2023
Infection et inflammation
2018-2022
Institut thématique Immunologie, inflammation, infectiologie et microbiologie
2020-2021
Diehl (Germany)
2019
Abstract Background Sepsis-associated brain dysfunction has been linked to white matter lesions (leukoencephalopathy) and ischemic stroke. Our objective was assess the prevalence of in septic shock patients requiring magnetic resonance imaging (MRI) for an acute neurologic change. Method Seventy-one were included a prospective observational study. Patients underwent daily neurological examination. Brain MRI obtained who developed focal deficit, seizure, coma, or delirium. Electroencephalogy...
Sepsis is associated with increased mortality, delirium and long-term cognitive impairment in intensive care unit (ICU) patients. Electroencephalogram (EEG) abnormalities occurring at the acute stage of sepsis may correlate severity brain dysfunction. Predictive value early standard EEG for mortality ICU septic patients remains to be assessed.In this prospective, single center, observational study, was performed, analyzed classified according both Synek Young scales, consecutive acutely...
Background. Neurofeedback (NF) training, as a method of self-regulation brain activity, may be beneficial in elderly patients with mild cognitive impairment. In this pilot study, we investigated whether sensorimotor (SMR)/ theta NF training could improve performance and electrical activity Methods. Twenty impairment (MCI) were assigned to 20 consecutive sessions during 10 weeks, on basis 2 each week. Neuropsychological assessments questionnaires well electroencephalogram (EEG) performed...
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes disease 2019 (COVID-19) through excessive end organ inflammation. Despite improved understanding of the pathophysiology, management, and great efforts worldwide to produce effective drugs, death rates COVID-19 patients remain unacceptably high, treatment is unfortunately lacking. Pharmacological strategies aimed at modulating inflammation in are being evaluated worldwide. Several drug therapies targeting this...
Background and purpose Deep sedation is associated with acute brain dysfunction increased mortality. We had previously shown that early-assessed brainstem reflexes may predict outcome in deeply sedated patients. The primary objective was to determine whether patterns of might mortality secondary generate a score predicting these Methods Observational prospective multicenter cohort study 148 non-brain injured patients, defined by Richmond Assessment Scale (RASS) <-3. Brainstem Glasgow Coma...
This study presents the outcome of 5-year-long French national project aiming at development and evaluation an effective brain-computer interface (BCI) prototype for communication patients with acute motor disabilities. It results from two clinical studies: a feasibility carried out partly in intensive care unit (ICU) innovative BCI prototype. In this second performance was compared to that healthy volunteers benchmarked against traditional assistive technology (scanning device). Altogether,...
Objective: Fatigue is one of the disabling sequelae traumatic brain injury (TBI), with repercussions on quality life, rehabilitation, and professional reintegration. Research needed effective interventions. We evaluated efficacy blue-enriched white light (BWL) therapy fatigue patients severe TBI. Setting: Physical Medicine Rehabilitation Physiology departments University hospitals. Participants: Adult symptoms following TBI, Severity Scale (FSS) score 4 or more, Epworth Sleepiness (ESS) 10...
We prospectively studied early bedside standard EEG characteristics in 61 acute postanoxic coma patients. Five simple features, namely, isoelectric, discontinuous, nonreactive to intense auditory and nociceptive stimuli, dominant delta frequency, occurrence of paroxysms were classified yes or no. Sensitivity, specificity, positive predictive value (PPV), negative (NPV), area under the receiver operating characteristic curve (AUC) each these variables for predicting an unfavorable outcome,...
Somatosensory (SSEP) and brainstem auditory (BAEP) evoked potentials are neurophysiological tools which, respectively, explore the intracranial conduction time (ICCT) intrapontine (IPCT). The prognostic values of prolonged cerebral times in deeply sedated patients have never been assessed. Sedated at risk developing new neurological complications, undetected. In this prospective observational bi-center pilot study, we investigated whether early impairment SSEP's ICCT and/or BAEP's IPCT could...
Older adults with Mild Cognitive Impairment (MCI) are at high risk of progressing to Alzheimer's disease (AD). Slowing down the effect dementia by enhancing brain plasticity represents one most prominent challenges. Neurofeedback (NF) has shown promising results in improving working memory but never been evaluated people MCI. We aim examine whether NF training can decrease cognitive disorders, targeting memory, attention functions and electrical activity elderly patients In this...