- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Neurological Disease Mechanisms and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced Neuroimaging Techniques and Applications
- Renal cell carcinoma treatment
- Advanced X-ray and CT Imaging
- Functional Brain Connectivity Studies
- Radiation Dose and Imaging
- Prostate Cancer Diagnosis and Treatment
- Ultrasound and Hyperthermia Applications
- Advanced Radiotherapy Techniques
- Lanthanide and Transition Metal Complexes
- Traumatic Brain Injury and Neurovascular Disturbances
- Head and Neck Cancer Studies
- Cerebrovascular and Carotid Artery Diseases
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Parkinson's Disease Mechanisms and Treatments
- Esophageal and GI Pathology
- Lung Cancer Diagnosis and Treatment
Shimane University
2013-2022
Teikyo University
2021
Shimane University Hospital
2012-2020
Matsudo City Hospital
2020
University Radiology
2020
Temple University
2010
Okayama University
2004-2009
Kyoto University Hospital
2002
Hyogo Brain and Heart Center
1996-2000
Osaka University of Pharmaceutical Sciences
1998
To delineate the features of regional cerebral metabolic rate glucose (CMRglc) in dementia with Lewy bodies (DLB).We compared absolute CMRglc 12 patients a clinical diagnosis DLB, Alzheimer's disease (AD), and normal volunteers (NC), using 18F-fluorodeoxyglucose (FDG) PET. The three groups were matched for age sex, there no differences duration or severity cognitive disturbances between DLB AD groups.CMRglc was significantly lower than that NC most parts brain, except sensorimotor cortices,...
To investigate the ability of T1 mapping liver on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging for estimation function.Local institutional review board approved this study. Ninety-one patients (64 men, 27 women; mean age, 67.4 years) were classified into 4 groups as follows: normal function (NLF), n = 16; chronic hepatitis (CH), 38; cirrhosis with Child-Pugh A (LCA), 20; and B (LCB), 17. Look-Locker sequences (single slice...
There have been conflicting results involving the clinical significance of white matter changes in patients with Alzheimer's disease (AD). We studied association between volume hyperintensities (WMHs) on T2-weighted images and cognitive, neurological, neuropsychiatric symptoms. The subjects were 76 AD who had WMHs but no obvious cerebrovascular diseases. quantified by using fast-fluid-attenuated inversion recovery whole brain atrophy 3D spoiled gradient-echo images. Effects dementia...
Both the magnitude of brain atrophy and premorbid size determine volume affected by Alzheimer's disease. To examine possibility that is a determinant cognitive reserve in patients with disease, relation between diffuse decline impact on were studied disease.By measuring whole intracranial 60 probable mild to moderate severity, use high-resolution magnetic resonance imaging image processing, authors functions. On basis normative brain-calvarium relationship derived from data an 28 healthy...
The authors studied 14 patients with dementia Lewy bodies (DLB), AD, and healthy control subjects N-isopropyl-p-[123I]iodoamphetamine SPECT. Comparison the statistical parametric mappings revealed that relative cerebral blood flow was lower in occipital lobes higher right medial temporal lobe DLB group than AD group. Decreased perfusion relatively well preserved are features distinguish from AD.
Everyday experience suggests that highly emotional events are often the most memorable. Experimental work in animals and humans has demonstrated amygdaloid complex plays a crucial role memory, i.e., memory of arousing strong emotions. The aim this study was to elucidate relationship between medial temporal damage impaired real-life patients with Alzheimer's disease.In 36 probable disease who experienced 1995 earthquake Kobe, Japan, memories surrounding were examined as an index use...
Dementia with Lewy bodies (DLB) is emerging as a common cause of degenerative dementia. A recent pathologic study has indicated that the medial temporal lobe in patients DLB was less atrophic than AD. The purpose this to examine whether MRI volumetry useful differentiate from AD clinically.We compared volumes hippocampal formation, amygdaloid complex, and whole brain 27 probable (based on criteria Consortium International Workshop), National Institute Neurological Disease Stroke/Alzheimer's...
Conventional T2-weighted (T2-WI) magnetic resonance imaging (MRI) has poor sensitivity for prostate transition-zone (TZ) cancer detection.To retrospectively evaluate the clinical value of diffusion-weighted MRI (DW-MRI) and dynamic contrast-enhanced (DCE-MRI) in combination with T2-WI diagnosis TZ cancer.Twenty-six cancers 23 patients at least one tumor (tumor size >10 mm) located predominantly were included study. Sixteen peripheral-zone (PZ) 12 PZ but without (control group) selected by...
Study Type – Prognosis (case series) Level of Evidence 4 What's known on the subject? and What does study add? A bone scan index (BSI) can quantify extent involvement response to treatment, but it has not been widely accepted, because its time‐consuming nature. The is first demonstrate that automated BSI calculated with a computer‐assisted diagnosis system effective in judging chemotherapeutic metastatic lesions patients castration‐resistant prostate cancer. OBJECTIVE To evaluate value an...
By using functional magnetic resonance imaging (fMRI), the neural substrates involved in mental recitation of single-digit multiplication table and serial subtraction were studied. The former depends mostly on well-learned arithmetical facts, while latter requires arithmetic processing. Activation during each task was compared with that a number counting control. During multiplication, activated regions included area lying along left intraparietal sulcus, premotor supplementary motor areas,...
To determine the features of cortical atrophy in frontotemporal dementia (FTD) and Alzheimer disease by using a hemispheric surface display generated with magnetic resonance (MR) images.The extent was evaluated automated MR volumetry 18 patients FTD matched disease. Results were compared those healthy, control subjects.Most regions significantly atrophic The frontal anterior temporal lobes more than mean hemispheric-to-intracranial volume ratio (56.2%) (58.4%) smaller subjects (66.0%)....
This paper proposes an automated procedure for segmenting magnetic resonance (MR) image of a human brain based on fuzzy logic. An MR volumetric composed many slice images consists several parts: gray matter, white cerebrospinal fluid, and others. Generally, the histogram shapes are different from person to person. Fuzzy information granulation histograms can lead series peaks. The intensity thresholds whole subject automatically determined by finding peaks obtained images. After these...
A neurologist witnessed the in-hospital onset of an ischemic stroke in a 71-year-old right-handed male who suddenly developed global aphasia and right hemiplegia. Diffusion-weighted magnetic resonance imaging (DWI) 39 minutes after ictus demonstrated high signals left internal carotid artery territory. T1- T2-weighted images failed to detect this change. Magnetic angiography showed occlusions branches anterior middle cerebral arteries atheromatous stenotic lesion ipsilateral proximal artery....
We examined 57 patients with mild Alzheimer's disease by using three kinds of verbal semantic memory tests (category fluency, confrontation naming and generation definition) correlated each score regional cerebral glucose metabolism determined (18)F-fluorodeoxyglucose positron emission tomography. The scores all significantly in the left inferior temporal gyrus, even after controlling for effects age, sex educational attainment. In contrast, word recall test did not correlate metaboliosm...