Hajime Kitagaki

ORCID: 0000-0002-9748-486X
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About
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Research Areas
  • MRI in cancer diagnosis
  • Advanced MRI Techniques and Applications
  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Radiomics and Machine Learning in Medical Imaging
  • Medical Imaging Techniques and Applications
  • Neurological Disease Mechanisms and Treatments
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Advanced Neuroimaging Techniques and Applications
  • Renal cell carcinoma treatment
  • Advanced X-ray and CT Imaging
  • Functional Brain Connectivity Studies
  • Radiation Dose and Imaging
  • Prostate Cancer Diagnosis and Treatment
  • Ultrasound and Hyperthermia Applications
  • Advanced Radiotherapy Techniques
  • Lanthanide and Transition Metal Complexes
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Head and Neck Cancer Studies
  • Cerebrovascular and Carotid Artery Diseases
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • Parkinson's Disease Mechanisms and Treatments
  • Esophageal and GI Pathology
  • Lung Cancer Diagnosis and Treatment

Shimane University
2013-2022

Teikyo University
2021

Shimane University Hospital
2012-2020

Matsudo City Hospital
2020

University Radiology
2020

Temple University
2010

Okayama University
2004-2009

Kyoto University Hospital
2002

Hyogo Brain and Heart Center
1996-2000

Osaka University of Pharmaceutical Sciences
1998

To delineate the features of regional cerebral metabolic rate glucose (CMRglc) in dementia with Lewy bodies (DLB).We compared absolute CMRglc 12 patients a clinical diagnosis DLB, Alzheimer's disease (AD), and normal volunteers (NC), using 18F-fluorodeoxyglucose (FDG) PET. The three groups were matched for age sex, there no differences duration or severity cognitive disturbances between DLB AD groups.CMRglc was significantly lower than that NC most parts brain, except sensorimotor cortices,...

10.1212/wnl.51.1.125 article EN Neurology 1998-07-01

To investigate the ability of T1 mapping liver on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging for estimation function.Local institutional review board approved this study. Ninety-one patients (64 men, 27 women; mean age, 67.4 years) were classified into 4 groups as follows: normal function (NLF), n = 16; chronic hepatitis (CH), 38; cirrhosis with Child-Pugh A (LCA), 20; and B (LCB), 17. Look-Locker sequences (single slice...

10.1097/rli.0b013e318200f67d article EN Investigative Radiology 2011-02-23

There have been conflicting results involving the clinical significance of white matter changes in patients with Alzheimer's disease (AD). We studied association between volume hyperintensities (WMHs) on T2-weighted images and cognitive, neurological, neuropsychiatric symptoms. The subjects were 76 AD who had WMHs but no obvious cerebrovascular diseases. quantified by using fast-fluid-attenuated inversion recovery whole brain atrophy 3D spoiled gradient-echo images. Effects dementia...

10.1161/01.str.31.9.2182 article EN public-domain Stroke 2000-09-01

Both the magnitude of brain atrophy and premorbid size determine volume affected by Alzheimer's disease. To examine possibility that is a determinant cognitive reserve in patients with disease, relation between diffuse decline impact on were studied disease.By measuring whole intracranial 60 probable mild to moderate severity, use high-resolution magnetic resonance imaging image processing, authors functions. On basis normative brain-calvarium relationship derived from data an 28 healthy...

10.1176/ajp.154.1.18 article EN American Journal of Psychiatry 1997-01-01

The authors studied 14 patients with dementia Lewy bodies (DLB), AD, and healthy control subjects N-isopropyl-p-[123I]iodoamphetamine SPECT. Comparison the statistical parametric mappings revealed that relative cerebral blood flow was lower in occipital lobes higher right medial temporal lobe DLB group than AD group. Decreased perfusion relatively well preserved are features distinguish from AD.

10.1212/wnl.53.2.413 article EN Neurology 1999-07-01

Everyday experience suggests that highly emotional events are often the most memorable. Experimental work in animals and humans has demonstrated amygdaloid complex plays a crucial role memory, i.e., memory of arousing strong emotions. The aim this study was to elucidate relationship between medial temporal damage impaired real-life patients with Alzheimer's disease.In 36 probable disease who experienced 1995 earthquake Kobe, Japan, memories surrounding were examined as an index use...

10.1176/ajp.156.2.216 article EN American Journal of Psychiatry 1999-02-01

Dementia with Lewy bodies (DLB) is emerging as a common cause of degenerative dementia. A recent pathologic study has indicated that the medial temporal lobe in patients DLB was less atrophic than AD. The purpose this to examine whether MRI volumetry useful differentiate from AD clinically.We compared volumes hippocampal formation, amygdaloid complex, and whole brain 27 probable (based on criteria Consortium International Workshop), National Institute Neurological Disease Stroke/Alzheimer's...

10.1212/wnl.51.2.357 article EN Neurology 1998-08-01

Conventional T2-weighted (T2-WI) magnetic resonance imaging (MRI) has poor sensitivity for prostate transition-zone (TZ) cancer detection.To retrospectively evaluate the clinical value of diffusion-weighted MRI (DW-MRI) and dynamic contrast-enhanced (DCE-MRI) in combination with T2-WI diagnosis TZ cancer.Twenty-six cancers 23 patients at least one tumor (tumor size >10 mm) located predominantly were included study. Sixteen peripheral-zone (PZ) 12 PZ but without (control group) selected by...

10.1080/02841850802508959 article EN Acta Radiologica 2008-11-22

Study Type – Prognosis (case series) Level of Evidence 4 What's known on the subject? and What does study add? A bone scan index (BSI) can quantify extent involvement response to treatment, but it has not been widely accepted, because its time‐consuming nature. The is first demonstrate that automated BSI calculated with a computer‐assisted diagnosis system effective in judging chemotherapeutic metastatic lesions patients castration‐resistant prostate cancer. OBJECTIVE To evaluate value an...

10.1111/j.1464-410x.2012.11355.x article EN BJU International 2012-07-12

By using functional magnetic resonance imaging (fMRI), the neural substrates involved in mental recitation of single-digit multiplication table and serial subtraction were studied. The former depends mostly on well-learned arithmetical facts, while latter requires arithmetic processing. Activation during each task was compared with that a number counting control. During multiplication, activated regions included area lying along left intraparietal sulcus, premotor supplementary motor areas,...

10.1046/j.1440-1819.2000.00739.x article EN Psychiatry and Clinical Neurosciences 2000-08-01

To determine the features of cortical atrophy in frontotemporal dementia (FTD) and Alzheimer disease by using a hemispheric surface display generated with magnetic resonance (MR) images.The extent was evaluated automated MR volumetry 18 patients FTD matched disease. Results were compared those healthy, control subjects.Most regions significantly atrophic The frontal anterior temporal lobes more than mean hemispheric-to-intracranial volume ratio (56.2%) (58.4%) smaller subjects (66.0%)....

10.1148/radiology.208.2.9680572 article EN Radiology 1998-08-01

This paper proposes an automated procedure for segmenting magnetic resonance (MR) image of a human brain based on fuzzy logic. An MR volumetric composed many slice images consists several parts: gray matter, white cerebrospinal fluid, and others. Generally, the histogram shapes are different from person to person. Fuzzy information granulation histograms can lead series peaks. The intensity thresholds whole subject automatically determined by finding peaks obtained images. After these...

10.1109/5326.885120 article EN IEEE Transactions on Systems Man and Cybernetics Part C (Applications and Reviews) 2000-01-01

A neurologist witnessed the in-hospital onset of an ischemic stroke in a 71-year-old right-handed male who suddenly developed global aphasia and right hemiplegia. Diffusion-weighted magnetic resonance imaging (DWI) 39 minutes after ictus demonstrated high signals left internal carotid artery territory. T1- T2-weighted images failed to detect this change. Magnetic angiography showed occlusions branches anterior middle cerebral arteries atheromatous stenotic lesion ipsilateral proximal artery....

10.1002/1531-8249(199906)45:6<794::aid-ana15>3.0.co;2-0 article EN Annals of Neurology 1999-06-01

We examined 57 patients with mild Alzheimer's disease by using three kinds of verbal semantic memory tests (category fluency, confrontation naming and generation definition) correlated each score regional cerebral glucose metabolism determined (18)F-fluorodeoxyglucose positron emission tomography. The scores all significantly in the left inferior temporal gyrus, even after controlling for effects age, sex educational attainment. In contrast, word recall test did not correlate metaboliosm...

10.1159/000051231 article EN Dementia and Geriatric Cognitive Disorders 2000-12-15
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