A5035613666- Neuroblastoma Research and Treatments
- Glioma Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Cardiac tumors and thrombi
- Childhood Cancer Survivors' Quality of Life
- Hematopoietic Stem Cell Transplantation
- Cancer Treatment and Pharmacology
- Acute Lymphoblastic Leukemia research
- Renal and related cancers
- Epigenetics and DNA Methylation
- Infectious Disease Case Reports and Treatments
- Cytomegalovirus and herpesvirus research
- Histiocytic Disorders and Treatments
- Brain Metastases and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Radiomics and Machine Learning in Medical Imaging
- Tuberous Sclerosis Complex Research
- Blood disorders and treatments
- Medical Imaging Techniques and Applications
- Pharmacogenetics and Drug Metabolism
- Bacterial Identification and Susceptibility Testing
- Adrenal and Paraganglionic Tumors
- Histone Deacetylase Inhibitors Research
Université Grenoble Alpes
2024-2025
Centre Hospitalier Universitaire de Grenoble
1998-2025
Institut Curie
1998
Université Joseph Fourier
1993
Inserm
1993
Abstract Background The aim of this study was to perform a description pediatric patients’ characteristics undergoing an allogeneic Hematopoietic Stem Cell Transplantation (HSCT) and identify their cytomegalovirus (CMV) serology status that donors Methods Patients under the age 18 who received HSCT in French center reporting data ProMISe database francophone society bone marrow transplant cellular therapy (SFGM-TC) during period comprised between January 1, 2019, December 31, 2021 Results...
Acute leukaemias represent the 1st cause of cancer in children. Their prognosis has improved significantly due to remarkable advances therapeutic management, despite risk long-term consequences, especially for patients who underwent allogenic hematopoietic stem cell transplantation (aHSCT). Through Leukaemia Children and Adolescents (LEA) follow-up cohort, we conducted a French national multicentre prospective study on occurrence factors chronic kidney disease (CKD), differentiating...
Abstract Purpose: The study of cell-free DNA (cfDNA) enables sequential analysis tumor cell–specific genetic alterations in patients with neuroblastoma. Experimental Design: Eighteen relapsing neuroblastoma having received lorlatinib, a third-generation ALK inhibitor, were identified (SACHA national registry and/or the institution). cfDNA was analyzed at relapse for nine and sequentially five (blood/bone marrow plasma) by performing whole-genome sequencing library construction followed...
Recent molecular advances have identified a novel sarcoma defined molecularly by oncogenic fusion of the genes CIC and DUX4 termed CIC-DUX4 sarcomas. The most common site involvement was trunk but some cases been described in head neck extremities. We report one first primitive renal sarcoma: 12-year-old boy who presented tumor, vena cava thrombus, lung metastases. morphological immunohistochemical analysis showed an undifferentiated sarcoma. Molecular demonstrated translocation, confirmed...
Spinal cord compression in Wilms' tumor (WT) is an extremely rare event that can have a very poor prognosis if not taken care of rapidly. Most cases reported the literature involve widely metastatic patient with bone or paraspinal metastases occasionally intradural metastasis. Here, we present case 3-year-old girl WT confirmed by biopsy, spinal due to direct contiguous spread through 2 vertebral foramina. Abdominal ultrasonography and magnetic resonance imaging performed for abdominal mass...
<div>AbstractPurpose:<p>The study of cell-free DNA (cfDNA) enables sequential analysis tumor cell–specific genetic alterations in patients with neuroblastoma.</p>Experimental Design:<p>Eighteen relapsing neuroblastoma having received lorlatinib, a third-generation <i>ALK</i> inhibitor, were identified (SACHA national registry and/or the institution). cfDNA was analyzed at relapse for nine and sequentially five (blood/bone marrow plasma) by performing...
<p>SupplemetaryFigure12345</p>
<div>AbstractPurpose:<p>The study of cell-free DNA (cfDNA) enables sequential analysis tumor cell–specific genetic alterations in patients with neuroblastoma.</p>Experimental Design:<p>Eighteen relapsing neuroblastoma having received lorlatinib, a third-generation <i>ALK</i> inhibitor, were identified (SACHA national registry and/or the institution). cfDNA was analyzed at relapse for nine and sequentially five (blood/bone marrow plasma) by performing...
<p>SupplemetaryFigure12345</p>