A5005629907- Antimicrobial Peptides and Activities
- Lipid Membrane Structure and Behavior
- Biochemical and Structural Characterization
- Occupational Health and Performance
- Aquaculture disease management and microbiota
- Neural Networks and Applications
- Parasite Biology and Host Interactions
- Maritime Navigation and Safety
- Human Health and Disease
- Protein Structure and Dynamics
- Hydrological Forecasting Using AI
University of Split
2021-2024
California Maritime Academy
2024
Antimicrobial peptides (AMPs) can be directed to specific membranes based on differences in lipid composition. In this study, we performed atomistic and coarse-grained simulations of different numbers the designed AMP adepantin-1 with a eukaryotic membrane, cytoplasmic Gram-positive Gram-negative membranes, an outer membrane. At core adepantin-1’s behavior is its amphipathic α-helical structure, which was implemented design. The structure promotes rapid self-association peptide water or upon...
Seafaring is considered one of the most stressful professions. Stressors in seafaring lead to typical symptoms stress, such as insomnia, loss concentration, anxiety, lower tolerance frustration, changes eating habits, psychosomatic and diseases, overall reduced productivity, with possibility burnout chronic responsibility syndrome. It has been previously determined that seafarers belong high-risk occupations terms developing metabolic syndrome, according their BMIs, almost 50% all overweight...
Kiadins are in silico designed peptides with a strong similarity to diPGLa-H, tandem sequence of PGLa-H (KIAKVALKAL) and single, double or quadruple glycine substitutions. They were found show high variability their activity selectivity against Gram-negative Gram-positive bacteria, as well cytotoxicity host cells, which influenced by the number placing residues along sequence. The conformational flexibility introduced these substitutions contributes differently peptide structuring...
This paper aims to highlight the important role of operations research, particularly simplex method, in solving everyday problems. To this end, a specific linear programming problem is considered paper. The will be solved using method. After problem, some useful conclusions drawn. following two sections provide an overview interesting ideas for future research and contribution then compared with contributions similar studies. Finally, study concludes its conclusion.
Adepantins are peptides designed to optimize antimicrobial biological activity through the choice of specific amino acid residues, resulting in helical and amphipathic structures. This paper focuses on revealing atomistic details mechanism action aligning design concepts with peptide behavior simulation results. Notably, Adepantin-1a exhibits a broad spectrum against both Gram-positive Gram-negative bacteria, while Adepantin-1 has narrow bacteria. The results showed that one main differences...
Artificial neural networks have been successfully used to model and predict water flows for a few decades.Different network types proven work better in different cases additional tools algorithms implemented improve those models.However, some problems still occur certain cases.This paper deals with the limitation of complex hydrological system inflow prediction using artificial time series.This is called lag it disables from giving accurate predictions.To eliminate extend horizon an...