Ali Talha Khalil

ORCID: 0000-0002-9848-8723
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About
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Research Areas
  • Nanoparticles: synthesis and applications
  • Essential Oils and Antimicrobial Activity
  • Moringa oleifera research and applications
  • Medicinal Plants and Neuroprotection
  • Advanced Nanomaterials in Catalysis
  • Phytochemistry and Bioactivity Studies
  • Graphene and Nanomaterials Applications
  • Nanoparticle-Based Drug Delivery
  • Phytochemicals and Antioxidant Activities
  • Phytochemicals and Medicinal Plants
  • Laser-Ablation Synthesis of Nanoparticles
  • Nanoplatforms for cancer theranostics
  • Viral Infections and Outbreaks Research
  • Insect and Pesticide Research
  • Geological Studies and Exploration
  • Geological and Geophysical Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Natural product bioactivities and synthesis
  • Cancer Genomics and Diagnostics
  • Natural Antidiabetic Agents Studies
  • Alzheimer's disease research and treatments
  • Phytochemistry and Biological Activities
  • scientometrics and bibliometrics research
  • Magnesium Oxide Properties and Applications
  • Carbon and Quantum Dots Applications

Lady Reading Hospital
2020-2025

Laboratoire de Chimie-Physique Macromoléculaire
2021-2024

Université de Lorraine
2021-2024

Institut des Molécules et Matériaux du Mans
2024

Centre National de la Recherche Scientifique
2010-2024

Le Mans Université
2024

Oniris
2023

University of Tikrit
2023

Ain Shams University
2023

St. George's University
2022

Cancer is a frightful disease and represents one of the biggest health-care issues for human race demands proactive strategy cure. Plants are reservoirs novel chemical entities provide promising line research on cancer. Hitherto, being effective, chemotherapy accompanied by certain unbearable side effects. Nevertheless, plants plant derived products revolutionizing field as these Simple, safer, eco-friendly, low-cost, fast, less toxic compared with conventional treatment methods....

10.1016/j.apjtb.2017.10.016 article EN Asian Pacific Journal of Tropical Biomedicine 2017-12-01

Sageretia thea (Osbeck.) was used as an effective chelating agent for the biosynthesis of iron oxide nanoparticles (IONP's) and extensively characterized through XRD, FTIR, Raman spectroscopy, Energy Dispersive Spectroscopy, HR-SEM/TEM SAED. Antibacterial assays against five human pathogenic bacterial strains were carried out minimum inhibitory concentrations calculated. Pseudomonas aeruginosa (MIC: 7.4 µg/mL) most susceptible strain to biosynthesized IONPs. All fungal showed susceptibility...

10.1080/17518253.2017.1339831 article EN cc-by Green Chemistry Letters and Reviews 2017-06-28

Cobalt oxide nanoparticles were successfully biosynthesized by complete green process using aqueous leaf extracts of Sageretia thea as chelating agent. Diverse techniques applied for characterization. Antibacterial (with and without UV illumination), antileishmanial, antioxidant enzyme inhibition applications assessed, while freshly isolated macrophages red blood cells used biocompatibility studies. Good antibacterial nature enhancement bactericidal upon modulation is reported....

10.1016/j.arabjc.2017.07.004 article EN cc-by-nc-nd Arabian Journal of Chemistry 2017-07-19

NiO nanoparticles are biosynthesized using Sageretia thea (Osbeck.) aqueous leave extracts and their biological activities reported. Nanoparticles (∼18 nm) were characterized through XRD, ATR-FTIR, EDS, SAED, HR-SEM/TEM Raman spectroscopy. Antibacterial activity was investigated against six pathogenic bacterial strains (gram positive gram negative) corresponding minimum inhibitory concentrations (MICs) calculated. UV-exposed to have reduced MICs relative the not been exposed UV. Moderate...

10.1080/21691401.2017.1345928 article EN Artificial Cells Nanomedicine and Biotechnology 2017-07-07

To investigate the physical and biological properties of Silybum marianum inspired ZnO nanoparticles (NPs), Ag-ZnO heterostructures. Experiment: Nanoparticles were characterized using ultraviolet-visible infrared spectroscopy, x-ray diffraction, high resolution electron microscopy, ζ potential thermo-gravimetric analysis etc. Results: Ag-ZnO-NPs indicated slightly higher antimicrobial then ZnO-NPs. Good antileishmanial (IC50 = 246 μg/ml for Ag-ZnO; 341 ZnO) antioxidant while moderate enzyme...

10.2217/nnm-2018-0279 article EN Nanomedicine 2019-02-04

Aim: To investigate the physical and biological properties of bioinspired zinc oxide (ZnO) nanoparticles via aqueous leaf extracts Sageretia thea. Experimental: Nanoparticles size approximately 12.4 nm were extensively characterized. In vitro antimicrobial, cytotoxic, biocompatible enzyme inhibition assays performed. Results: Significant antimicrobial activities with without UV illumination are reported. Bioinspired ZnO found effective against fungal strains. MTT assay was performed to check...

10.2217/nnm-2017-0124 article EN Nanomedicine 2017-07-12

Silver nanoparticles are among the most significant diagnostic and therapeutic agents in field of nanomedicines. In current study, green chemistry approach was made to optimize a cost-effective synthesis protocol for silver from aqueous extract important anticancer plant Fagonia indica. We investigated potential possible involvement AgNPs apoptosis. The biosynthesized stable (zeta potential, -16.3 mV) spherical with crystal size range 10 60 nm. MTT cell viability assay shows...

10.1155/2020/1215395 article EN cc-by Oxidative Medicine and Cellular Longevity 2020-10-05

Aqueous floral extracts of Callistemon viminalis were used to synthesize Fe2O3 nanoparticles (IONPs) which intensively characterized through UV-vis, X-ray diffraction, HR-SEM/HR-TEM, Fourier- transform infrared spectroscopy (FTIR) and energy dispersive (EDS). Their physical properties studied in response different annealing temperatures. It was observed that the increase temperature produced small-sized nanoparticles. The nanoparticle size calculated as 32, 26 22 nm for at 300, 400 500 °C,...

10.1080/21691401.2018.1434534 article EN Artificial Cells Nanomedicine and Biotechnology 2018-02-05

The medicinal importance of a novel plant Olax nana Wall. ex Benth. (family: Olacaceae) was revealed for the first time via HPLC-DAD finger printing, qualitative phytochemical analysis, antioxidant, cholinesterase, and α-glucosidase inhibitory assays.The crude methanolic extract O. (ON-Cr) subjected to analysis printing. antioxidant potential ON-Cr assessed 1,1-diphenyl,2-picrylhydrazyl (DPPH), 2,2-azinobis[3-ethylbenzthiazoline]-6-sulfonic acid (ABTS) hydrogen peroxide (H2O2) free radical...

10.1186/s12906-017-2057-9 article EN cc-by BMC Complementary and Alternative Medicine 2018-01-02

Green and ecofriendly route for biosynthesis of lead oxide nanoparticles has been successfully demonstrated using aqueous leaf extracts Sageretia thea (Osbeck.). Biosynthesized PbO (∼27 nm) were extensively characterized XRD, FTIR, Raman, EDS etc. Morphology was studied through HR-TEM/SEM. As synthesized investigated their iv-vitro biological properties. Antibacterial activities revealed enhancement upon modulation by UV in a concentration dependent manner. Pseudomonas aeruginosa found to be...

10.1016/j.arabjc.2017.08.009 article EN cc-by-nc-nd Arabian Journal of Chemistry 2017-09-01

The present study aims to evaluate phytochemical and pharmacological potentials of Dysphania ambrosioides (L.) Mosyakin & Clemants previously known as Chenopodium L. Extraction was carried out using 14 solvents with wide range polarity find the best solvent system for each bioactivity. Total phenolic flavonoids contents were measured colorimetrically polyphenolics quantified via HPLC-DAD analysis. samples screened inhibitory against free radicals, leishmania, cancer cell lines, protein...

10.1080/14786419.2018.1437428 article EN Natural Product Research 2018-02-12

Green synthesis of nanoparticles is an emerging field nanotechnology, preferred over physical and chemical owing to their safety, cost-effectiveness nature, bio-compatibility, eco-friendly scalable properties. The present study includes Seripheidium quettense aqueous extract mediated green synthesis, optimization silver (Sq-AgNPs) pharmacological evaluations. Synthesis was done considering various parameters including concentrations AgNO3, pH the reaction mixture, precursor ratio...

10.1080/17518253.2019.1643929 article EN cc-by Green Chemistry Letters and Reviews 2019-07-03

Aim: To demonstrate synthesis of cerium oxide nanoparticles (CeO2 NPs) by a green method using Hyphaene thebaica, and investigate their therapeutic applications. Materials & methods: Structural, vibrational luminescent properties were established x-ray diffraction, Fourier transformed infrared spectroscopy, Raman ultraviolet absorption selected area electron microscopy photolumincence spectroscopy. Therapeutic different in vitro assays. Results: CeO2 NPs determined to be crystalline nature...

10.2217/nnm-2019-0368 article EN Nanomedicine 2020-02-01
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