Raduan Hage

ORCID: 0000-0002-9858-4774
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About
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Research Areas
  • Photodynamic Therapy Research Studies
  • Laser Applications in Dentistry and Medicine
  • Corneal Surgery and Treatments
  • Cerebrovascular and Carotid Artery Diseases
  • Pulmonary Hypertension Research and Treatments
  • Medical and Biological Ozone Research
  • Porphyrin and Phthalocyanine Chemistry
  • Bee Products Chemical Analysis
  • Nanoplatforms for cancer theranostics
  • Heart Rate Variability and Autonomic Control
  • Cardiovascular Conditions and Treatments
  • Surgical Simulation and Training
  • Turtle Biology and Conservation
  • Meat and Animal Product Quality
  • Physiological and biochemical adaptations
  • Organ Transplantation Techniques and Outcomes
  • Microbial Inactivation Methods
  • Myasthenia Gravis and Thymoma
  • Effects of Environmental Stressors on Livestock
  • Cardiac Valve Diseases and Treatments
  • Pelvic floor disorders treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiovascular Syncope and Autonomic Disorders
  • Simulation-Based Education in Healthcare
  • Ocular Infections and Treatments

Universidade do Vale do Paraíba
2001-2021

Universidade Paulista
2012-2018

Universidade Federal de São Paulo
2006-2012

Leiden University Medical Center
1999

Clinique du Grand Large
1993

This study aimed to describe the clinical results of intrahemorrhoidal application a diode laser.Hemorrhoids are common source pain, and no surgical technique achieves painless outcome. Endovascular laser therapy for varicose veins as described in an experimental is method that could be used treatment hemorrhoids, but there few trials literature.Fifteen patients with second third degree hemorrhoids underwent therapy. After piles were identified, fiber was introduced into each it irradiated...

10.1089/pho.2008.2368 article EN Photomedicine and Laser Surgery 2009-08-29

Liver fibrosis is characterized by excessive accumulation of extracellular matrix components in the liver parenchyma that distorts normal architecture and hepatic function. Progressive could end advanced stage known as cirrhosis, resulting need to resort transplantation. Amniotic membrane (AM) has emerged an innovative therapeutic approach for chronic diseases due its anti-inflammatory, antiscarring, wound-healing effects. We have recently shown AM can be used a patch on surface at same time...

10.3727/096368916x692645 article EN Cell Transplantation 2016-08-02

The aim of this work was to evaluate the association low-level laser therapy (LLLT, 830 nm) and calcitonin in bone repair considering that healing remains a challenge health professionals. Calcitonin has antiosteoclastic action LLLT is treatment uses lasers or light-emitting diodes alter cellular function. Both are used improve healing. Densitometry clinical noninvasive valuable tool mineral density (BMD). Sixty male rats were submitted defect with trephine bur, randomly divided into four...

10.1155/2012/829587 article EN cc-by International Journal of Photoenergy 2012-01-01

Ingested or penetrating foreign bodies are common in veterinary medicine. When they radiolucent, these objects become a diagnostic challenge, but can be investigated sonographically. However, successful object identification depends on the skill of sonographer. Considering that cases appear randomly during hospital routines, it is not always possible to train all students identify them correctly. Therefore, aim this study was produce homemade simulations radiolucent for student...

10.1152/advan.00163.2015 article EN AJP Advances in Physiology Education 2017-02-01

This study aimed to investigate the pharmacokinetics of a hematoporphyrin derivative in colonic tumors induced by dimethylhydrazine and adjacent normal colon Wistar rats using an vivo fluorescence spectroscopy technique. In conventional clinical application photodynamic therapy, interval between photosensitizer (PS) administration lesion illumination is often standardized without taking into account variations due type or localization tumor intrinsic differences microcirculation vascular...

10.1155/2012/615259 article EN cc-by International Journal of Photoenergy 2012-01-01

A six-year old Holstein cow with an eye cancer (ocular squamous cell carcinoma) involving the third eyelid and conjunctiva was submitted to photodynamic therapy using intratumoral 20% aminolevulinic acid (5-ALA - Aldrich Chemical Company, Milwaukee, USA) a light emitting diode (LED VET LED MMOptics<sup>(R)</sup>) wavelength between 600 700 nm, 2 cm diameter circular beam, power of 150 mW, dose 50 J/cm<sup>2</sup> as source irradiation. Fifteen days after experimental procedure we observed...

10.1117/12.701316 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2007-02-08

Photodynamic Therapy (PDT) is an emerging and promising therapeutic modality for treatment of a wide variety malignant nononcologic tumors, as well in the infected skin ulcers. This study evaluated effectiveness PDT to treat chronic wound that had been already subjected several clinical surgical type treatments dog. The animal with 8 cm diameter left leg received injection aqueous solution 1% methylene blue (MB) 2% lidocaine into lesion. After MB was irradiated using LED (LED-VET...

10.1117/12.761679 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2008-01-22

The assessment of heart rate variability (HRV) by linear methods in conjunction with Poincaré plots can be useful for evaluating cardiac regulation the autonomic nervous system and diagnosis prognosis disease snakes. In this report, we describe an analysis HRV conscious adult corn snakes Pantherophis guttatus (P. guttatus). electrocardiogram (ECG) parameters were determined (8 females, 13 males) used analysis, RR interval was analyzed time frequency domains. There no sex-related difference...

10.33448/rsd-v10i11.19781 article EN Research Society and Development 2021-09-01

Biomedical applications of near-infrared Raman spectroscopy have increased their importance at the last ten years. This technique can determinate molecular composition materials, allowing a sensible and fast biological diagnosis. It has showed to be promising tool for health diagnosis due its high sensibility. Colorectal cancer (CRC) is one most common malignant tumors in humans beings. In decades many experimental models been developed animals based use chemical composites induce formation...

10.1117/12.699690 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2007-02-08

As espécies de Candida estão entre as principais causas infecção da corrente sanguínea, promovendo elevados índices mortalidade, sendo a albicans espécie mais frequente em infecções hospitalares. Atualmente, diversos medicamentos antifúngicos são utilizados, porém podem ser tóxicos ao hospedeiro e, com o seu uso excessivo, leveduras têm adquirido resistência tratamento convencional. O objetivo do presente estudo é avaliar os efeitos associação Terapia Fotodinâmica (PDT) Azul Metileno óleo...

10.18066/revistaunivap.v24i44.380 article PT cc-by Revista Univap 2018-06-29

The purpose of this work was to determine a radiographic standard normality for lateral and medial ungulae in 3-year-old bovine females the Nellore breed. Twenty-six cows underwent exposure hindlimbs forelimbs; abaxioaxial projections were used. images analyzed; distances measured between dorsal surface distal phalanx hoof capsule. two angles formed, i.e., an angle line parallel sole (inner), (outer), also recorded. results suggested proximal, middle forelimbs: 0.96 ± 0.12 cm. For...

10.1111/ahe.12416 article EN Anatomia Histologia Embryologia 2018-12-03

A growing number of studies have demonstrated that autofluorescence and induced fluorescence spectroscopy can be used to distinguish normal abnormal tissues in vivo. Through photochemical accumulation atherosclerotic lesions it is possible obtain fluorescence, this has been many researches. The aim study was diagnose, by aluminum phthalocyanine transadventitial plaques artery wall rabbits. Five male Norfolk rabbits were submitted a high level cholesterol diet for 9 weeks. When the blood...

10.1117/12.427832 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2001-05-21

Photodynamic therapy (PDT) has been widely studied in the last decades and it is becoming a promising tool treatment of tumors many kinds. PDT based on photoactivation sensitized drug that restrained tumor cells, producing highly reactive species can destroy tumoral cells with minimum collateral effect. This study aimed to evaluate effect induced neoplasias colon by 1,2-dimetilhidrazine rats, using as photosensitizing chloroaluminum phthalocyanine incorporated liposomes compare methods...

10.1117/12.644973 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2006-02-09

Introdução: Malassezia spp. é um gênero leveduriforme, comumente isolado da microbiota normal do conduto auditivo de cães, que possui espécies associadas a otites externas e dermatites atópicas. O plasma elétrico considerado o quarto estado matéria, vem sendo empregado na descontaminação esterilização. Objetivo: Avaliar os efeitos alta frequência, utilizando dois diferentes eletrodos vidro, [RH1] redução crescimento cepas clínicas leveduras Material Métodos: Nove amostras spp., isoladas cães...

10.18606/2318-1419/amazonia.sci.health.v7n3p2-11 article PT cc-by-nc-nd Amazônia Science & Health 2019-09-27

Comparative studies were carried out on the Al- phthalocyanine and Zn-phthalocyanine uptake in iliac artery wall of rabbit, through transadventitial fluorescence measurements. Two 3.5 Kg Norfolk make rabbit used. The was dissected, isolated clamped at two points, 1.5 cm apart. experiment comprised three steps, collecting spectra several point inside outside region artery. excitation source a 488 nm Argon Laser. Firstly, it measured pre post clamping without photosensitizer. After that, 50...

10.1117/12.437057 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2001-08-14

The Transmissible Venereal Tumor (TVT) is a very common neoplasic disease in free-roaming dogs which affects the extern genital and presenting resistance to conventional drugs that promote high toxicity. Photodynamic Therapy (PDT) based tumor cells irradiation after absorption of photosensitizer substance. At present, protoporphirin IX (PP IX) has been explored PDT due be endogen, then it does not present toxicity effect. This substance can obtained by exogenous way through aminolevulinic...

10.1117/12.477857 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2003-07-22

O presente estudo teve como objetivo comparar os efeitos de dois protocolos pré-anestésicos sobre parâmetros fisiológicos, eletrocardiográficos e o grau sedação em cadelas que seriam submetidas a ovário-salpingo-histerectomia. Vinte animais foram divididos forma randomizada grupos (n=10) acordo com protocolo empregado, grupo 1 (G1: dexmedetomidina + metadona) 2 (G2: midazolam). Foram coletados dados (frequência cardíaca respiratória; pressão arterial sistólica; eletrocardiograma) antes...

10.34188/bjaerv5n1-055 article PT Brazilian Journal of Animal and Environmental Research 2022-02-17
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