A5078034013- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Non-Invasive Vital Sign Monitoring
- Cardiovascular Health and Disease Prevention
- Anesthesia and Neurotoxicity Research
- Airway Management and Intubation Techniques
- Nausea and vomiting management
- Neonatal Respiratory Health Research
- Pain Management and Opioid Use
- Acute Kidney Injury Research
- Infant Development and Preterm Care
- Kawasaki Disease and Coronary Complications
- Respiratory Support and Mechanisms
- Head and Neck Surgical Oncology
- Nerve Injury and Rehabilitation
- Hip and Femur Fractures
- Orthopedic Surgery and Rehabilitation
- Neonatal Health and Biochemistry
- Ultrasound in Clinical Applications
- Meta-analysis and systematic reviews
- Clinical Nutrition and Gastroenterology
- Blood Pressure and Hypertension Studies
- Spine and Intervertebral Disc Pathology
Agostino Gemelli University Polyclinic
2021-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2024
Università Cattolica del Sacro Cuore
2023-2024
Intraoperative hypotension (IOH) is associated with increased morbidity and mortality. Hypotension Prediction Index (HPI) a machine learning derived algorithm that predicts IOH shortly before it occurs. We tested the hypothesis application of HPI in combination pre-defined Goal Directed Therapy (GDT) hemodynamic protocol reduces during major gynaecologic oncologic surgery. enrolled women scheduled for surgery under general anesthesia invasive arterial pressure monitoring. Patients were...
Abstract Intraoperative hypotension (IOH) is common during major surgery and associated with a poor postoperative outcome. Hypotension Prediction Index (HPI) an algorithm derived from machine learning that uses the arterial waveform to predict IOH. The aim of this study was assess diagnostic ability HPI working non-invasive ClearSight system in predicting impending patients undergoing gynaecologic oncologic (GOS). In retrospective analysis hemodynamic data were downloaded Edwards...
Arterial hypotension is common after spinal anesthesia (SA) for cesarean delivery (CD), and to date, there no definitive method predict it. The prediction index (HPI) an algorithm that uses the arterial waveform early phases of intraoperative hypotension. aims this study were assess diagnostic ability HPI working with waveforms detected by ClearSight system in predicting impending awake patients, agreement pressure values recorded conventional noninvasive blood (NIBP) monitoring patients...
Abstract Background Neuromuscular blocking agents (NMBAs) are routinely used in anesthesia practice. An undetected, incomplete recovery of neuromuscular function at the end surgery potentially exposes patients to clinical deterioration postoperative period. The aim this study was investigate incidence residual blockade (RNMB) a cohort receiving NMBAs. Methods We enrolled 90 spontaneously breathing adult admitted room (RR) after completion surgeries having received least 1 dose NMBA....
Multisystem inflammatory syndrome in children (MIS-C) is a severe hyperinflammatory disease related to SARS-CoV2 infection, with frequent cardiovascular involvement the acute setting. The aim of study was evaluate cardiac function at 6 months. Thirty-two patients diagnosed MIS-C were enrolled and underwent advanced echocardiogram discharge According left ventricular ejection fraction (LVEF) admission, divided into group A (LVEF < 45%) B ≥ follow-up results compared. At discharge, all had...
( Anesth Analg . 2022;134:633–643) Many consider spinal anesthesia (SA) the foremost method for cesarean delivery, but previous studies show this can lead to hypotension. A research team determined effectiveness of noninvasive hypotension prediction index (HPI) algorithm, an algorithm using high-fidelity arterial pressure waveform recordings and 22 additional features measure likelihood a hypotensive event on scale from 1 100, in predicting This study assessed ability HPI ClearSight system...
ESP block (ESPB) and posterior Quadratus Lumborum Block (pQLB) have been proposed as opioid-sparing techniques for the management of pain after abdominal surgery. Between December 2021 October 2022, we conducted a retrospective comparative study at delivery suite Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, to compare efficacy ESPB pQLB in preventing postoperative an elective caesarean section (CS). The primary outcome was total morphine consumption first 24 h....
BACKGROUND: The posterior quadratus lumborum block (pQLB) has been used in postoperative pain management after cesarean section (CS). However, clinicians have no data about pQLB safety pregnants, at increased risk of local anesthetic systemic toxicity (LAST). purpose the present study was to explore efficacy and adding epinephrine ropivacaine for bilateral vs. performed with alone CS.METHODS: In this prospective trial 52 ASA 2 physiological status, were consecutively allocated one two...
Background: Few studies in the literature have analyzed long-term neurodevelopmental outcomes of administration a multicomponent versus soybean-based lipid emulsion (LE) preterm infants receiving parenteral nutrition (PN). A recent randomized controlled trial conducted our unit provided evidence better growth head circumference during hospital stay those who received LE. Methods: This is 24 month follow-up study infants, previously enrolled trial, LE (SMOFlipid®) or standard one...
The term THRIVE refers to the delivery of 100% heated and humidified oxygen via a nasal cannula maintain viable gas exchange during prolonged apnea. There are no reports its application for Operative Hysteroscopy (OH) under general anesthesia (GA). aim study is investigate success rate as unique airway management technique in this setting. results will support development randomized controlled trial (RCT) demonstrate non-inferiority compared traditional techniques.Twenty consecutive ASA I-II...
Brachial plexus injury is a serious peripheral nerve that severely disables upper limbs and affects patients' daily life work Acupuncture Electroacupuncture have traditionally been used to treat neuropathic pain. However, there still lacking evidence as regard their effects on pain following traumatic lesions. Neurotmesis after brachial also causes movement disorders of the denervated muscles loss sensory function in skin.We report case due humeral fracture, predominantly involving lower...
Reducing a child's level of anxiety before magnetic resonance imaging (MRI) procedures allows for better behavioral outcomes. The aim this retrospective study was to evaluate anxiolytic efficacy Midazolam/γ-cyclodextrin oral formulation. We retrospectively reviewed 100 medical charts children who, between 1 February and 31 July 2022, underwent MRI under general anesthesia with or without premedication midazolam/γ-cyclodextrin. Primary outcome comparison behavior facemask positioning, while...
Abstract Background Left uterine displacement (LUD) has been questioned as an effective strategy to prevent aortocaval compression after spinal anesthesia (SA) for cesarean delivery (CD). We tested if LUD a significant impact on cardiac output (CO) in patients undergoing CD under SA during continuous non-invasive hemodynamic monitoring with Clearsight. Methods Forty-six were included the final analysis. considered 4 timepoints of 5 min each: T1 = baseline LUD; T2 without T3 T4 LUD. was then...
Acute kidney injury is a frequent complication for critical newborns. Its management significant challenge, especially in extremely low-birth-weight (ELBW) infants. Currently, peritoneal dialysis (PD) the most manageable treatment. However, data are lacking regarding when diuresis can be declared irreversible relative to start of PD. A female infant born at 28 + 0 weeks with birth weight 800 g by monochorionic diamniotic pregnancy, complicated twin-to-twin transfusion syndrome, developed...
Abstract Background: Left uterine displacement (LUD) has been questioned as an effective strategy to prevent aortocaval compression after spinal anesthesia (SA) for cesarean delivery (CD). We tested if LUD a significant impact on cardiac output (CO) in patients undergoing CD under SA during continuous non-invasive hemodynamic monitoring.Methods: Forty-six were included the final analysis. considered 4 timepoints of 5 minutes each: T1=baseline with LUD; T2=baseline without T3=after T4=after...