A5048463584- Physiological and biochemical adaptations
- Cancer, Hypoxia, and Metabolism
- Aquaculture disease management and microbiota
- RNA modifications and cancer
- High Altitude and Hypoxia
- Cancer-related molecular mechanisms research
- Fish Biology and Ecology Studies
- Identification and Quantification in Food
- Genetic diversity and population structure
- Dental Health and Care Utilization
- Molecular Biology Techniques and Applications
- Oral microbiology and periodontitis research
- Mitochondrial Function and Pathology
- Fish Ecology and Management Studies
- Heat shock proteins research
- Genetics, Bioinformatics, and Biomedical Research
- Cancer Genomics and Diagnostics
- Gut microbiota and health
- Aquaculture Nutrition and Growth
- Lung Cancer Treatments and Mutations
- Southeast Asian Sociopolitical Studies
- HIV/AIDS oral health manifestations
- Genetic and phenotypic traits in livestock
- Metabolomics and Mass Spectrometry Studies
- Adipose Tissue and Metabolism
King George's Medical University
2020-2021
National Bureau of Fish Genetic Resources
2011-2019
Indian Council of Agricultural Research
2012-2013
Abstract This study provides the first high-quality draft genome assembly (762.5 Mb) of Tenualosa ilisha that is highly contiguous and nearly complete. We observed a total 2,864 contigs, with 96.4% completeness N 50 2.65 Mbp largest contig length 17.4 Mbp, along complete mitochondrial 16,745 bases. A number 33,042 protein coding genes were predicted, among these, 512 classified under 61 Gene Ontology (GO) terms, associated various homeostasis processes. Highest belongs to cellular calcium...
Retrospective analysis has already shown correlation between severe Chronic Periodontitis (CP) cases with human papiloma virus (HPV). Hence, we aimed to explore deep-seated infected granulation tissue removed during periodontal flap surgery procedures for residential bacterial species HPV+ and HVP- CP cases, which may serve as good predisposition marker oral cancer. All CP-granulation samples showed the prominence of Firmicutes, Proteobacteria, Bacteroidetes phyla an abundance gram negative...
Highly keratinized oral squamous cell carcinoma (OSCC) exhibits an improved response to treatment and prognosis compared with weakly OSCC. Therefore, we aimed develop gene transcript signature identify novel full-length isoforms, fusion non-coding RNA differentiate well-differentiated (WD) Moderately Differentiated (MD)/Poorly (PD)/WD-lymphadenopathy OSCC through, HTA, Isoform sequencing, NanoString. Additionally, specific copy number gain loss were also in WD through Oncoscan array...
The selection of most appropriate reference gene(s) is a crucial step in studies quantifying gene expression by quantitative real-time PCR (qPCR). As need should be unaffected at transcription level experimental conditions and/or tissue types. In this study, 11 candidate genes were tested Clarias batrachus for their stability using the geNorm, NormFinder and BestKeeper statistical algorithms, compared different tissues (brain, heart, liver, muscle, spleen head kidney) treatments (before...
This article documents the addition of 96 microsatellite marker loci to Molecular Ecology Resources Database. Loci were developed for following species: Clarias batrachus, Marmota himalayana, Schizothorax richardsonii, Sitophilus zeamais and Syagrus romanzoffiana. These cross-tested on dussumeri, gariepinus, Heteropneustus fossilis, granarius oryzae.
Smoking has been associated with increased risk of periodontitis. The aim the present study was to compare periodontal disease severity among smokers and nonsmokers which may help in better understanding predisposition this chronic inflammation mediated diseases. We selected deep-seated infected granulation tissue removed during flap surgery procedures for identification differential abundance residential bacterial species through long-read sequencing technology targeting full-length 16S...
Heterogeneity of non-small cell lung carcinoma (NSCLC) among patients is currently not well studied. Pathologic markers and staging systems have been a precise predictor the prognosis an individual patient. Hence, we hypothesize to develop transcript-based signature categorize stage IIIA-NSCLC in adenocarcinoma (LUAD) squamous (LUSC), plus identify that could indicate disease.Human Transcriptome Array 2.0 (HTA) NanoString nCounter® platform were used for high-throughput gene-expression...
Complete mitogenome sequence for Anguilla bengalensis (family Anguillidae) was generated through third-generation sequencing platform. The 16 714 bp mitgenome contained 13 protein-coding genes, 22 transfer RNAs, 2 ribosomal and a non-coding (control) region. gene order identical to that observed in most of the other vertebrates. comparison complete Indian mottled eel during this study with two subspecies did not agree taxonomic status three considered as one species.
Santosh Kumar Rai, Weaving Hierarchies: Handloom Weavers in Early Twentieth Century United Provinces (Delhi: Primus, 2021), xx + 515 pp., ₹1,595, ISBN: 9789390737758 (Hardback).
Abstract Large and increasing public-databases of oral squamous cell carcinoma (OSCC) transcriptome sequencing data has been generated through next-generation which limitation for novel full-length transcript isoforms. Hence, our objective was to identify differential specific OSCC-related full length isoforms, long noncoding RNA fusion genes compared non-matched oral-cavity control samples PacBio-RSII platform. The OSCC, patients from different anatomical sites (gingivobuccal region,...
Abstract Medulloblastoma is the most common malignant pediatric brain tumor with a high mortality rate. A comprehensive protein-coding and regulatory transcriptomics needed to understand four major molecular subgroups. Molecularly sub-classified 22 histo-pathologically characterized (MB) into group4-MB (G4), group3-MB (G3), Wnt-MB SHH-MB two approved methods were used Molecular Inversion Probe based Array (Oncoscan Array) transcript-probe-based Nanostring assay. For 2-control, normal tissue...
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a significant challenge worldwide. Rapid genome sequencing of SARS-CoV-2 is going on across the globe to detect mutations and genomic modifications in SARS-CoV-2. In this study, we have sequenced twenty-three positive samples collected during first pandemic from state Uttar Pradesh, India. We observed range already reported (2-22), including; D614G, L452R, Q613H, Q677H, T1027I S gene; S194L N Q57H, L106F,...