A5028433709- Blood Pressure and Hypertension Studies
- Metabolism, Diabetes, and Cancer
- Sodium Intake and Health
- Hormonal Regulation and Hypertension
- Cutaneous Melanoma Detection and Management
- Diabetes Management and Research
- Cardiovascular Issues in Pregnancy
- Pain Management and Opioid Use
- Heart Rate Variability and Autonomic Control
- Blood disorders and treatments
- Infectious Diseases and Mycology
- Cancer, Lipids, and Metabolism
- Platelet Disorders and Treatments
- Melanoma and MAPK Pathways
- Diverticular Disease and Complications
- Cancer survivorship and care
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Clusterin in disease pathology
- Blood groups and transfusion
- Diet and metabolism studies
- Cardiovascular Health and Disease Prevention
Fukushima Medical University
2021
Daiichi-Sankyo (Japan)
2015-2018
Daiichi Sankyo (Germany)
2015
Using data from the large-scale HONEST (Home blood pressure measurement with Olmesartan Naive patients to Establish Standard Target pressure) study, we investigated characteristics of effects olmesartan-based treatment on morning hypertension in Asian hypertensive patients. Specifically, relationship between baseline (BP) and BP reduction after 16 weeks by linear regression analyses; determinants were also investigated. For both home (MHBP) clinic (CBP), reduced systolic (SBP) was associated...
Hypertension guidelines recommend using the average of two home blood pressure (HBP) measurements obtained on one occasion to monitor pressure. We studied prognostic value first and second or their during follow-up period, as well relationships among difference between HBP prognosis data from HONEST (HBP measurement with Olmesartan-Naive patients Establish Standard Target pressure) study. During mean 2.02 years follow-up, 280 had cardiovascular events. Hazard ratios (HRs) for events each 1...
The appropriate target blood pressure (BP) in elderly patients with hypertension remains uncertain. We investigated the relationship between morning home systolic (MHSBP) during follow-up and cardiovascular (CV) risk outpatients receiving olmesartan-based treatment aged <75 years (n = 16799) ≥75 4792) HONEST study. In period (mean 2.02 years), for major CV events was significantly higher MHSBP ≥155 mmHg compared <125 both age groups Cox proportional hazards model adjusted other factors there...
We here report a 21-year-old male who presented with acute myelomonocytic leukemia (AMML) associated acquired von Willebrand syndrome (AVWS). To our knowledge, this is the first case of AVWS caused by AMML. In case, following remission-induction chemotherapy combined idarubicin and cytarabine, patient showed remarkable improvement bleeding symptoms due to AVWS. Moreover, after an allogeneic stem cell transplantation from sibling donor, both AMML maintain complete remission.
Objective: There has been no agreement among guidelines on the number of measurements home blood pressure (BP) that should be taken each occasion. The prognostic value first, second, and difference between first second in on-treatment BP was studied. Design method: In HONEST (Home measurement with Olmesartan Naive patients to Establish Standard Target pressure) Study, a prospective 2-year observational study an angiotensin receptor blocker, olmesartan-based treatment outpatients essential...
直腸胆門部悪性黒魚腫の3例を報告した.3例中2例では,触診や内視鏡所見から本疾患を疑うことはできず,また生検を採取した2例中1例は印環細胞癌,他の1例は低分化腺癌と報告され,悪性黒色腫の術前診断は得られなかった,3例中2例では,直腸切断術およびOK432とDTIC,ACNU,Vincristine(DAV療法)による免疫化学療法が,他の1例では,直腸切断術とBCG療法が施行された.全例,血行性およびリンパ行性転移をきたして8～29カ月後に死亡した.1983年までの本邦報告例を分析し,自験例と合わせて本疾患の診断と治療における問題点を検討した.