A5043926620- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Oral and Maxillofacial Pathology
- Facial Nerve Paralysis Treatment and Research
- Tracheal and airway disorders
- Head and Neck Anomalies
- Boron Compounds in Chemistry
- Thyroid Cancer Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Hedgehog Signaling Pathway Studies
- Esophageal and GI Pathology
- Voice and Speech Disorders
- Neuroblastoma Research and Treatments
- Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Dysphagia Assessment and Management
- Vascular Malformations and Hemangiomas
- Tumors and Oncological Cases
- Radiopharmaceutical Chemistry and Applications
- Sarcoma Diagnosis and Treatment
- Orthodontics and Dentofacial Orthopedics
- Vascular Tumors and Angiosarcomas
- Foreign Body Medical Cases
Osaka University of Pharmaceutical Sciences
2021-2025
Japan Cancer Society
2025
Tokushima University
2024
American Association of Orthodontists
2024
Osaka Medical and Pharmaceutical University
2013-2022
Osaka National Hospital
2009
Abstract Purpose Since June 2020, boron neutron capture therapy (BNCT) has been a health care service covered by insurance in Japan to treat locally advanced or recurrent unresectable head and neck cancers. Therefore, we aimed assess the clinical outcomes of BNCT as treatment explore its role among standard modalities for Materials Methods We retrospectively analyzed data from patients who were treated using at Kansai Medical Center, Osaka Pharmaceutical University, between 2020 May 2022....
Objective The aim of this study was to evaluate the rate postoperative facial palsy in benign parotid tumors, as well its risk factors, pathology, and clinical results. Study Design Retrospective analysis. Methods We performed a retrospective analysis data from patients whose initial operation for tumor had been our department between 1999 2020. Results included 1,018 study. most common observed pleomorphic adenoma (614 patients), followed by Warthin (234 patients). Fine‐needle aspiration...
The present study reports the case of a 25‑year‑old male patient with salivary gland secretory carcinoma (SC) ETV6::RET gene fusion. presented left parotid mass and was treated using superficial parotidectomy. Histological analysis tumor demonstrated combination cystic, follicular trabecular patterns in cells, eosinophilic secretions vacuolated cytoplasm. Tumor cells exhibited infiltrative growth into muscle nerve tissues, accompanied by central stromal hyalinized sclerosis....
This study investigated the clinical outcomes of patients with parotid carcinoma at a single institution during an 18-year period, focus on diagnosis, treatment, and survival. The subjects were 171 treated our department period from September 1999 to August 2017. There 19 in stage I, 65 II, 22 III, IV. symptoms, preoperative node metastasis, survival rate, prognostic factors, immunohistological findings investigated. Preoperative diagnosis histological grade by fine-needle aspiration...
Objective This study aimed to investigate the correlation of craniofacial morphology with maxillary sinus and evaluate whether orthodontic treatment facilitates enlargement in adults. Materials methods A total 45 adult women underwent cephalography computed tomography before after treatment. All participants were classified into three groups: skeletal class I, II, III. The average dimensions volume calculated each subgroup. Furthermore, multiple regression analysis was used analyze...
It is appropriate to clinically classify benign parotid tumors into three groups, i.e. superficial tumors, deep and lower pole tumors.It important based on location when deciding the surgical strategy conducting clinical research. In this study, we examined a classification of that was useful for practice.We studied 425 patients with who underwent surgery at our hospital. Their age, gender, tumor histopathology, maximum diameter, postoperative facial nerve paresis, operating time, blood loss...
6092 Background: Salivary gland cancer is rare and has various pathological subtypes. With this rarity heterogeneity, the therapeutic contribution of chemotherapy, including immune checkpoint inhibitors, for recurrent or metastatic salivary (RM-SGC) not been elucidated. The purpose trial was to investigate efficacy safety nivolumab patients with platinum-refractory RM-SGC. Methods: This open-label, single-arm, multicenter phase II conducted at 9 centers in Japan. Eligible had measurable...
The purpose of this study was to prepare the ultrasonographic diagnostic criteria on parotid tumors for preoperative differentiation superficial and deep tumors.We evaluated 154 patients with a benign tumor who underwent surgery. minimum thickness normal gland tissue between parotideomasseteric fascia (minimum fascia-tumor distance [MFTD]) measured ultrasonography compared among at different locations, optimum cutoff value differentiate identified.The MFTD showed significant differences...
Parotid gland cancer (PGC) is a rare malignancy and its molecular characteristics remain poorly understood, which has precluded the development of effective drug therapies. Given poor prognosis many human cancers in tropomyosin receptor kinase B (TRKB) highly expressed, we investigated involvement brain-derived neurotrophic factor (BDNF)/TRKB pathway PGC cells using clinical specimens observed upregulation TRKB BDNF. In primary culture systems patient-derived cancer-associated fibroblasts...
Abstract Background When determining treatment strategy for a salivary gland tumor, assessing histology and malignancy grade before surgery is essential. Several new diagnostic classification systems cytology have recently been proposed. However, none incorporate of malignancy. Methods We developed system that incorporates tumors (OMC classification), consisting 11 categories. Our OMC was applied to 1175 patients who had preoperative confirmed final pathological diagnosis available from the...