A5063165561- Ear and Head Tumors
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Cancer Studies
- Adrenal and Paraganglionic Tumors
- Pituitary Gland Disorders and Treatments
- Ear Surgery and Otitis Media
- Voice and Speech Disorders
- Peripheral Neuropathies and Disorders
- Oral and Maxillofacial Pathology
- Congenital Ear and Nasal Anomalies
- Tracheal and airway disorders
- Glioma Diagnosis and Treatment
- Facial Nerve Paralysis Treatment and Research
- Proteoglycans and glycosaminoglycans research
- Parvovirus B19 Infection Studies
- Cancer, Hypoxia, and Metabolism
- Viral-associated cancers and disorders
- Head and Neck Surgical Oncology
Osaka Medical and Pharmaceutical University
2013-2019
This study investigated the clinical outcomes of patients with parotid carcinoma at a single institution during an 18-year period, focus on diagnosis, treatment, and survival. The subjects were 171 treated our department period from September 1999 to August 2017. There 19 in stage I, 65 II, 22 III, IV. symptoms, preoperative node metastasis, survival rate, prognostic factors, immunohistological findings investigated. Preoperative diagnosis histological grade by fine-needle aspiration...
Hyaluronan (HA) and its binding molecules, cartilage link protein (LP) proteoglycan (PG), are structural components of the hydrated extracellular matrix. Because these molecules play important roles in tumor microenvironment, we examined distribution HA, LP, versican, aggrecan salivary gland tumors using histochemical immunohistochemical methods, including double staining. LP was present pleomorphic adenoma (PA) adenoid cystic carcinoma (ACC) tissues, absent malignant that investigated....
In children and adolescents under 20 years of age, tumors the parotid gland are relatively rare. A total 14 patients with benign 7 malignant were treated at Osaka Medical College Hospital between 1999 2016. Pleomorphic adenoma was most frequent neoplasm, while frequently encountered neoplasm mucoepidermoid carcinoma, followed by acinic cell carcinoma. Fine-needle aspiration cytology is useful important for making a preoperative histological diagnosis, especially tumors. Perioperative frozen...
Objectives: (1) Estimate the degree of postoperative aeration in middle ear after canal wall down tympanoplasty with soft‐wall reconstruction (CWD SWR) for cholesteatoma. (2) Characterize relationship between and hearing outcome. (3) Propose an ideal state order to obtain satisfactory outcome CWD SWR. Methods: This retrospective study was conducted our tertiary referral hospital 2001 2013. Seventy‐eight ears cholesteatoma treated surgically at by planned two‐stage SWR were included....
Objectives: (1) Compare longitudinal changes of Varicella‐zoster virus (VZV)‐specific cell‐mediated immunity (CMI) in Hunt syndrome with Bell's palsy using IFN‐γ enzyme‐linked immunospot (ELISPOT). (2) Examine the role VZV‐specific CMI for VZV reactivation facial nerve syndrome. Methods: This prospective study was conducted our tertiary referral hospital between 2010 and 2013. Nineteen 59 patients were enrolled. Mononuclear cells isolated from whole blood incubated antigen culture plates 40...
Paraganglioma represent vascular neoplastic tumors that arise from chemoreceptors located in the wall of blood vessels or are associated with specific nerves. The site origin defines name given to these tumors, and they most commonly occur at carotid bifurcation where known as body (CBT). A malignant form CBT, CBT is uncommon. We report herein on a case 70-year-old woman. patient complained lateral cervical mass right side four years previously. tumor had become gradually larger tender....
Paraganglioma represent vascular neoplastic tumors that arise from chemoreceptors located in the wall of blood vessels or are associated with specific nerves. The site origin defines name given to these tumors, and they most commonly occur at carotid bifurcation where known as body (CBT). A malignant form CBT, CBT is uncommon. We report herein on a case 70-year-old woman. patient complained lateral cervical mass right side four years previously. tumor had become gradually larger tender....
Objective 1) Discuss the effects of ventilation tube placement on postoperative mastoid growth in children with otitis media effusion (OME). 2) Show an incidence complication, for example, spontaneous extrusion, permanent tympanic membrane perforation. Method In total, 177 tubes were inserted 148 ears 81 OME a mean age 5.5 years at our hospital from 2001 to 2009. Long‐term used: The T‐Tube (Goode) 87 cases or Type II (Paparella) 90 cases. Results fell out spontaneously 46%: 61% group and 32%...
In children and adolescents under 20 years of age, tumors the parotid gland are relatively rare. A total 14 patients with benign 7 malignant were treated at Osaka Medical College Hospital between 1999 2016. Pleomorphic adenoma was most frequent neoplasm, while frequently encountered neoplasm mucoepidermoid carcinoma, followed by acinic cell carcinoma. Fine-needle aspiration cytology is useful important for making a preoperative histological diagnosis, especially tumors. Perioperative frozen...
耳下腺癌は症例数が少なく，また悪性度の低い症例もあるため長期間の観察が必要であり治療成績を検討することが容易でない。1999年9月から2019年2月までの約19年間に当科で加療を施行した耳下腺癌新鮮症例は184例であった。ステージ別ではステージⅠが22例，Ⅱが71例，Ⅲが23例，Ⅳが68例であった。悪性度別では低・中悪性が105例，高悪性が79例であった。主な組織型は粘表皮癌が47例，多形腺腫由来癌が27例，腺様囊胞癌が21例，唾液導管癌が15例，分泌癌が12例，腺房細胞癌が11例であった。症例全体の疾患特異的5年生存率は76.6％であった。ステージ別の疾患特異的5年生存率はステージⅠが100％，Ⅱが97.7％，Ⅲが71.6％，Ⅳが51.6％であった。悪性度別の疾患特異的5年生存率は，低/中悪性が95.9％，高悪性が46.1％であった。高悪性癌は最も大きな予後不良因子であるが，術前の悪性度診断は必ずしも良好ではなかった。