Aditya B. Char

ORCID: 0000-0002-9910-1244
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Research on Leishmaniasis Studies

University of Glasgow
2019

Targeting parasite's protein kinase Malaria elimination goals are constantly eroded by the challenge of emerging drug and insecticide resistance. Alam et al. have taken established targets—CLK kinases involved in regulation RNA splicing—and investigated how inhibition enzymes blocks completion its complex life cycle. They identified an inhibitor CLK that was 100-fold less active against most closely related human effective at clearing rodent malaria parasites. Not only does this compound...

10.1126/science.aau1682 article EN Science 2019-08-29
Coming Soon ...