About
Contact & Profiles
A5034228619
Research Areas
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Trace Elements in Health
Thomas Jefferson University
2020
MicroRNA-31 (miR-31) is overexpressed in esophageal squamous cell carcinoma (ESCC), a deadly disease associated with dietary Zn deficiency and inflammation. In deficiency-promoted rat ESCC model miR-31 up-regulation, cancer-associated inflammation, high burden following N -nitrosomethylbenzylamine (NMBA) exposure, systemic antimiR-31 delivery reduced incidence from 85 to 45% ( P = 0.038) gene knockout abrogated development of 1 × 10 −6 ). Transcriptomics, genome sequencing, metabolomics...
10.1073/pnas.1920333117
article
EN
cc-by-nc-nd
Proceedings of the National Academy of Sciences
2020-03-02
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