A5102926893- Iron Metabolism and Disorders
- Vector-borne infectious diseases
- Renal and related cancers
- Inflammatory Bowel Disease
- Trace Elements in Health
- Animal Nutrition and Physiology
- Immune Cell Function and Interaction
- Herpesvirus Infections and Treatments
- Chronic Kidney Disease and Diabetes
- IL-33, ST2, and ILC Pathways
- interferon and immune responses
- Animal Virus Infections Studies
- Aquaculture disease management and microbiota
- Biochemical effects in animals
- Heat shock proteins research
- Antimicrobial Peptides and Activities
- Streptococcal Infections and Treatments
- Microbial infections and disease research
- Mesenchymal stem cell research
- Pharmacological Effects of Natural Compounds
- Galectins and Cancer Biology
- Immunodeficiency and Autoimmune Disorders
- Insect and Pesticide Research
- Natural product bioactivities and synthesis
- Cancer-related molecular mechanisms research
Northeast Agricultural University
2011-2022
Education Department of Heilongjiang Province
2020-2021
First Affiliated Hospital of GuangXi Medical University
2021
Guangxi Medical University
2021
Objective: To investigate the immunological mechanism of bone marrow-derived mesenchymal stem cells (BM-MSCs) in inflammatory bowel disease (IBD). Methods: Mice with 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis were intraperitoneally injected phosphate-buffered saline, BM-MSCs, BM-MSCs tumor necrosis factor-induced protein 6 (Tnfaip6) knockdown mediated by RNA interference recombinant adenovirus, and BM-MSCs-infected control adenovirus or mouse Tnfaip6. The activity index,...
Abstract Background Reticuloendotheliosis virus (REV) is a retrovirus that causes severe immunosuppression in poultry. Animals grow slowly under conditions of oxidative stress. In addition, long-term stress can impair immune function, as well accelerate aging and death. This study aimed to elucidate the pathogenesis REV from perspective changes oxidative-antioxidative function following infection. Methods A total 80 one-day-old specific pathogen free (SPF) chickens were randomly divided into...
Reticuloendotheliosis virus (REV) is a type C avian retrovirus that causes immunosuppression, dwarf syndrome, and lymphoma in infected hosts. In this study, we used tandem mass tag (TMT) labeling liquid chromatography–tandem spectrometry (LC-MS/MS) to characterize protein alterations chicken bursa of Fabricius, before after REV infection at 7, 14, 21, 28 days. Our data showed 1,127, 999, 910, 1,138 differentially expressed proteins were significantly altered days infection, respectively....
100 chicks were randomly divided into probiotics group(P group), Newcastle disease (ND) vaccine group(V ND group (P+V group)and normal group(N group). The dynamic changes of T lymphocytes number in the cecal tonsil, gland Harder, and Peyer's patch duodenum ileum vaccinated with at 0,7,14,28 42 days post vaccination determined by using paraffin section acid nonspecifica-naphthyl acetate esterase (ANAE) staining method. results showed that numbers above immune tissue P+V V was significantly...
Abstract Background Reticuloendotheliosis virus (REV) is a retrovirus that causes severe immunosuppression in infected poultry. Under oxidative stress,the animals grow slowly. In addition, long-term stress can impair immune function, as well accelerate the aging and death of animal.This study aimed to elucidate pathogenesis REV from perspective changes oxidative-antioxidative function following infection. Results specific pathogen free chickens with REV, levels H 2 O MDA thymus increased,...
Abstract Iron is a mineral that the body acquires from environment in order to maintain physiological function; however, excessive iron causes disease. The aim of this work investigate processes by which diets induces kidney fibrosis sheep disorders their inflammatory factors. All were fed basal diet supplemented with 50 (CON), 500 (L-iron), 1000 (M-iron), and 1500 (H-iron) mg Fe/kg as ferrous sulfate monohydrate (FeSO 4 ·H 2 O), respectively. Hematoxylin-Eosin (H&E), Perls, Masson...
Abstract Iron is a mineral that the body acquires from environment in order to maintain physiological function; however, excessive iron causes disease. The aim of this work investigate processes by which diets induces kidney fibrosis sheep disorders their inflammatory factors. All were fed basal diet supplemented with 50 (CON), 500 (L-iron), 1000 (M-iron), and 1500 (H-iron) mg Fe/kg as ferrous sulfate monohydrate (FeSO4·H2O), respectively. Hematoxylin-Eosin (H&E), Perls, Masson staining...
Introduction: Iron is a mineral that the animals body acquires from environment in order to maintain physiological function; however, excessive iron causes disease.Objective: The aim of this work was investigate processes by which diets induces kidney fibrosis sheep disorders their inflammatory factors.Methods: All were fed basal diet supplemented with 50 (CON), 500 (L-iron), 1000 (M-iron), and 1500 (H-iron) mg Fe/kg as ferrous sulfate monohydrate (FeSO4·H2O), respectively. Hematoxylin-Eosin...
Abstract Background: In recent years, the number of visits to Crohn's disease (CD) has gradually increased, but its pathogenesis is still unclear 1 .This research aimed explore potential molecular pathways and immune disorders CD. Methods: The two gene datasets GSE83448 GSE95095 were used identify differentially expressed genes (DEGs) in our study. We also carried out function enrichment analyses DEGs between CD group control group.xCell types lymphocytes microenvironment. Subsequently,...