Hybrid nanomaterials offer potential scope for an increasing number of novel applications when engineered to deliver usefully functional properties. Recent advancements in the design new material products that result from interactions among different compositions at nanoscale and microscale has led innovative ways fabricate process hybrids with altered structural physicochemical An example is development "lubricants" make use ionic liquids (ILs) their ability induce exploitable molecular...

Rational engineering and assimilation of diverse chemo- biocatalytic functionalities in a single nanostructure is highly desired for efficient multistep chemical reactions but has so far remained elusive. Here, we design synthesize multimodal catalytic nanoreactors (MCNRs) based on mesoporous metal-organic framework (MOF). The MCNRs consist customizable metal nanocrystals stably anchored enzymes the mesopores, as well coordinatively unsaturated cationic MOF nodes, all within nanoreactor...

Abstract Nanostructures converting chemical energy to mechanical work by using benign metabolic fuels, have huge implications in biomedical science. Here, we introduce Au/Pt‐based Janus nanostructures, resembling “egg‐in‐nest” morphology ( Au/Pt‐EN s), showing enhanced motion as a result of dual enzyme‐relay‐like catalytic cascade physiological biomedia, and turn molecular‐laden transport living cells. We developed dynamic‐casting approach silica yolk‐shell nanoreactors: first, install large...

Next-generation catalysts are urgently needed to tackle the global challenge of antimicrobial resistance. Existing antimicrobials cannot function in complex and stressful chemical conditions found biofilms, as a result, they unable infiltrate, diffuse into, eradicate biofilm its associated matrix. Here, we introduce mixed-FeCo-oxide-based surface-textured nanostructures (MTex) highly efficient magneto-catalytic platforms. These systems can produce defensive ROS over broad pH range...

Abstract Cellulose can be converted into 5‐bromomethylfurfural (BMF), a brand new biofuel or intermediate, in 80 % yield by treatment with HBr and LiBr continuous extraction toluene. From other carbohydrates straw, BMF was also obtained high yields. The mechanism of formation investigated, the results indicate that this furfural is formed during depolymerization cellulose glucose not an intermediate.

Nanoreactors, in which the reactions are remotely controlled by magnetic fields, potentially valuable bioorthogonal chemistry for future applications. Here, we develop a silica-confined magnetothermia-induced nanoreactor (MAG-NER) selectively growing Pd nanocrystals on preinstalled iron-oxide core inside hollow silica nanoshell. The growth is achieved induction. interfacial catalytic site activated stimulating localized magnetothermia, and nanocompartmentalization realized size-selective...

Unlike homogeneous metal complexes, achieving absolute control over reaction selectivity in heterogeneous catalysts remains a formidable challenge due to the unguided molecular adsorption/desorption on metal-surface sites. Conventional organic surface modifiers or ligands and rigid inorganic metal-organic porous shells are not fully effective. Here, we introduce concept of "ligand-porous shell cooperativity" desirably switch catalysis. We present nanocatalyst design strategy consisting...

ConspectusThe extensive research performed in the past two decades has enabled production of a range colloidal nanocrystals, mostly through solution-based procedures that generate and transform nanostructures bulk-phase solutions containing precursors surfactants. However, understanding control each nanocrystal (trans)formation step during synthesis are still complicated because high complexity this process, which multiple diverse events such as nucleation, subsequent growth, attachment,...

Abstract Harnessing the power of cell biocatalysis for sustainable chemical synthesis requires rational integration living cells with modern synthetic catalysts. Here, we develop silica-tiling strategy that constructs a hierarchical, inorganic, protocellular confined nanospace around individual to accommodate molecularly accessible abiotic catalytic sites. This empowers microorganisms new-to-nature without compromising cellular regenerative process. Yeast cell, widely used biocatalyst, is...

Installing well‐defined high density single‐atomic catalyst (SAC) sites is highly desired for the synergistic cooperative effect in efficient chemical synthesis but elusive to synthesize due unavoidable atomic segregation into clusters or particulates. We implemented a 2D‐nanoconfined SAC grafting strategy. Inside bilayer silica envelope, single metal hydroxide layer, pre‐loaded with catalytic (Pt, Pd, Ir) precursors, underwent controlled thermal conversion homogeneously embedded SACs...

Installing well-defined high density single-atomic catalyst (SAC) sites is highly desired for the synergistic cooperative effect in efficient chemical synthesis but elusive to synthesize due unavoidable atomic segregation into clusters or particulates. We implemented a 2D-nanoconfined SAC grafting strategy. Inside bilayer silica envelope, single metal hydroxide layer, pre-loaded with catalytic (Pt, Pd, Ir) precursors, underwent controlled thermal conversion homogeneously embedded SACs...

Artificial nanoreactors that can facilitate catalysis in living systems on-demand with the aid of a remotely operable and biocompatible energy source are needed to leverage chemical diversity expediency advanced synthesis biology medicine. Here, we designed synthesized plasmonically integrated (PINERs) highly tunable structure NIR-light-induced synergistic function for efficiently promoting unnatural catalytic reactions inside cells. We devised synthetic approach toward PINERs by...

Abstract Rational engineering and assimilation of diverse chemo‐ biocatalytic functionalities in a single nanostructure is highly desired for efficient multistep chemical reactions but has so far remained elusive. Here, we design synthesize multimodal catalytic nanoreactors (MCNRs) based on mesoporous metal‐organic framework (MOF). The MCNRs consist customizable metal nanocrystals stably anchored enzymes the mesopores, as well coordinatively unsaturated cationic MOF nodes, all within...

A number of structurally novel polyhydroxylated quinolizidines have been prepared starting from 2-deoxyglycosylamines which in turn were derived D-glycals by following a methodology developed our laboratory. In strategy, Grignard reaction and ring-closing metathesis (RCM) reactions are the key steps to construct desired skeletons. All synthesized final molecules checked for glycosidase inhibition activity, some found be selective certain glycosidases.

Abstract The syntheses of D ‐ and L ‐fagomines 1 , 4 5 6 their isomers from starting ‐glycals have been achieved. involve elaboration common amino alcohol precursors obtained 2‐deoxy‐1‐amino sugar derivatives. key steps in the are intramolecular reductive amination N‐heterocyclization. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

Interest and challenges remain in designing synthesizing catalysts with nature-like complexity at few-nm scale to harness unprecedented functionalities by using sustainable solar light. We introduce "nanocatalosomes"-a bio-inspired bilayer-vesicular design of nanoreactor metallic bilayer shell-in-shell structure, having numerous controllable confined cavities within interlayer space, customizable different noble metals. The intershell-confined plasmonically coupled hot-nanospaces the play a...

Despite the enormous application potential, methods for conformal few-atomic-layer deposition on colloidal nanocrystals (NCs) are scarce. Similar to process of lamination, we introduce a "confine and shine" strategy homogeneously modify different surface curvatures plasmonic NCs with ultrathin layers diverse catalytic noble metals. This self-limited epitaxial skinlike metal growth harvests localized plasmon resonance induce reduction chemistry directly NC surface, confined inside hollow...

Herein, by choosing few-nm-thin two-dimensional (2D) nanocrystals of MOF-5 containing in-planner square lattices as a modular platform, crystal lattice-guided wet-chemical etching has been rationally accomplished. As result, two attractive pore patterns carrying Euclidean curvatures; precisely, plus(+)-shaped and fractal-patterned pores via ⟨100⟩ ⟨110⟩ directional etching, respectively, are regulated in contrast to habitually formed spherical-shaped random etches on MOF surface. In agreement...

O-Benzyl-protected C-2 formyl glycals are regioselectively deprotected and acetylated first at C-3 then C-6 upon treatment with a ZnCl2−Ac2O−AcOH reagent combination. Treatment of the thus-obtained acetate various nucleophiles leads to substitution retention stereochemistry in galactal series, whereas mixed results were obtained glucal-derived compounds. Two azido-substituted products converted into corresponding β-sugar amino acids.

Here, we describe and conceptualize the influence of surface engineering for hollow manganese oxide nanoparticles (HMONs)-based contrast agents magnetic resonance imaging (MRI). A systematic study has been conducted enhancing relaxivities HMONs by functionalizing their with various capping ligands having different anchoring groups (carboxylate, alcohol, thiol, amine). Among all studied ligands, carboxylate-anchored exhibit significant increase in magnetization value upon HMON. Contrary to...

Abstract Nanostructures converting chemical energy to mechanical work by using benign metabolic fuels, have huge implications in biomedical science. Here, we introduce Au/Pt‐based Janus nanostructures, resembling “egg‐in‐nest” morphology ( Au/Pt‐EN s), showing enhanced motion as a result of dual enzyme‐relay‐like catalytic cascade physiological biomedia, and turn molecular‐laden transport living cells. We developed dynamic‐casting approach silica yolk‐shell nanoreactors: first, install large...

A variety of alcohols react with 2,3,4,6-tetra-O-acetyl-1,5-anhydro-D-arabino-hex-1-enopyranose 1 in the presence a catalytic amount HClO4 supported on silica gel to give corresponding alkyl 3-deoxy-hex-2-enopyranosides 2 high yield, short reaction times (10–45 mins) and good α-selectivity. Work-up merely involves filtration reagent, followed by chromatographic purification crude product. This methodology has also been employed synthesis bicyclic ether, useful precursor for cyclic...